Characterization of the multixenobiotic resistance (MXR) mechanism in embryos and larvae of the zebra mussel (Dreissena polymorpha) and studies on its role in tolerance to single and mixture combinations of toxicants

Aquatic Toxicology

Volumn 101, Issue 1, 2011, Pages 78-87

  Faria, Melissa ^a   Navarro, Ana ^a   Luckenbach, Till ^b   Piña, Benjamin ^a   Barata, Carlos ^a  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

^b HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

Freshwater; Larvae; Mixture toxicity; Multixenobiotic resistance (MXR); Musk fragrances; MXR inhibitors; Zebra mussel

Indexed keywords

CYCLOSPORIN A; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; TOXIC SUBSTANCE; VERAPAMIL; VERLUKAST; VINBLASTINE; XENOBIOTIC AGENT;

BIOASSAY; EMBRYO; ENVIRONMENTAL RISK; FRESHWATER ECOSYSTEM; GENE EXPRESSION; MOLLUSC; RISK ASSESSMENT; SUBSTRATE PREFERENCE; TOXICOLOGY; XENOBIOTICS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DREISSENA; EMBRYO; GENE EXPRESSION; IC 50; LARVA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TOXICITY TESTING; XENOBIOTIC METABOLISM;

ANIMALS; BIOLOGICAL TRANSPORT; CYCLOSPORINE; DREISSENA; DRUG RESISTANCE, MULTIPLE; DRUG TOLERANCE; EMBRYO, NONMAMMALIAN; INDANS; LARVA; OLIGOPEPTIDES; P-GLYCOPROTEIN; PROPIONATES; QUINOLINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHODAMINES; RISK ASSESSMENT; VERAPAMIL; XENOBIOTICS;

DREISSENA POLYMORPHA; MAMMALIA;

EID: 78649907353     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2010.09.004     Document Type: Article

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