Emerging contaminants - Pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 552, Issue 1-2, 2004, Pages 101-117

  Smital, Tvrtko ^a   Luckenbach, Till ^b   Sauerborn, Roberta ^a   Hamdoun, Amro M ^b   Vega, Rebecca L ^b   Epel, David ^b  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Environmental pollutants; Multixenobiotic resistance (MXR); MXR inhibitors; Pesticides; PPCPs; Synthetic musk fragrances

Indexed keywords

CARRIER PROTEIN; CHLOROQUINE; COLCHICINE; CYCLOSPORIN A; CYTOCHALASIN D; DIMETHOATE; DIMPYLATE; EMETINE; ENDOSULFAN; ETOPOSIDE; FENOXYCARB; GLYCOPROTEIN P; GYRASE INHIBITOR; MALATHION; MITOMYCIN C; PESTICIDE; PETROLEUM; PHOSALONE; PIRIMICARB; PROTEIN INHIBITOR; QUINIDINE; RHODAMINE B; THIAMAZOLE; VERAPAMIL; VINBLASTINE; XENOBIOTIC AGENT;

APOPTOSIS; AQUATIC ENVIRONMENT; AQUATIC FAUNA; CONCENTRATION (PARAMETERS); ECOTOXICOLOGY; ENVIRONMENTAL EXPOSURE; HUMAN; MICROBIAL DEGRADATION; MUSSEL; NONHUMAN; PHENOTYPE; POLLUTANT; POLLUTION; PRIORITY JOURNAL; PROTEIN TRANSPORT; REVIEW; SEA URCHIN; WATER CONTAMINATION; WATER POLLUTION;

ANIMALS; BACTERIA; DRUG RESISTANCE, MULTIPLE; FISHES; MOLLUSCA; PESTICIDES; PETROLEUM; WATER POLLUTANTS, CHEMICAL; XENOBIOTICS;

ECHINOIDEA;

EID: 3843094824     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2004.06.006     Document Type: Review

References (60)

1. Kurelec B. The multixenobiotic resistance mechanism in aquatic organisms. Crit. Rev. Toxicol. 22:1992;23-43
2. Epel D. Use of multidrug transporters as first lines of defense against toxins in aquatic organisms. Comp. Biochem. Physiol. A. 120:1998;23-28
3. Smital T., Kurelec B. The chemosensitizers of multixenobiotic resistance mechanism in aquatic invertebrates: a new class of pollutants. Mutat. Res. 399:1998;43-53
4. Kurelec B. Reversion of the multixenobiotic resistance mechanism in gills of marine mussel Mytilus galloprovincialis by a model inhibitor and environmental modulators of P170-glycoprotien. Aquat. Toxicol. 33:1995;93-103
5. Kurelec B., Waldmann P., Zahn R.K. The modulation of functional and toxic expression of the induced multixenobiotic resistance mechanism in a clam Corbicula fluminea. Mar. Environ. Res. 42:1996;383-387
6. Smital T., Kurelec B. The concentrations of inhibitors of multixenobiotic resistance mechanism in natural waters: the direct in vivo demonstration of their effect. Environ. Toxicol. Chem. 16:1997;2164-2170
7. Kurelec B., Britvić S., Pivèević B., Smital T. Fragility of multixenobiotic resistance in aquatic organisms enhances the complexity of risk assessment. Mar. Environ. Res. 46:1998;415-419
8. Bard S.M. Multixenobiotic resistance as a cellular defense mechanism in aquatic organisms. Aquat. Toxicol. 48:2000;357-389
9. Johnstone P.A., Stringer R.L., Santillo D. Effluent complexity and ecotoxicology: regulating the variable within varied systems. Toxicol. Ecotoxicol. News. 3:1996;115-120
10. Daughton C.G., Ternes T.A. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ. Health Persp. 107:1999;907-938
11. Higgins C.F., Gallagher M.P., Mimmack M.M., Pearce S.R. A family of closely related ATP-binding subunits from prokaryotic and eukaryotic cells. Bioessays. 8:1988;111-116
12. Dean M., Rzhetsky A., Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome. Res. 11:2001;1156-1166
13. Danø K. Cross resistance between vinca alkaloids and anthracyclines in Ehrlich ascites tumor in vivo. Cancer Chemother. Rep. 56:1972;701-708
14. Juliano R.L., Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta. 455:1976;152-162
15. Gottesman M.M., Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62:1993;385-427
16. Litman T., Druley T.E., Stein W.D., Bates S.E. From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell. Mol. Life Sci. 58:2001;931-959
17. Scala S., Akhmed N., Rao U.S., Paull K., Lan L., Dikstein B., Lee J., Elgemeie G.H., Stein W.D., Bates S.E. P-glycoprotein substrates and antagonists cluster into two distinct groups. Mol. Pharmacol. 51:1997;1024-1033
18. Lee J.S., Paull K., Alvarez M., Hose C., Monks A., Grever M., Fojo A.T., Bates S.E. Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen. Mol. Pharmacol. 46:1994;627-638
19. Cole S.P.C., Bhardwaj G., Gerlach J.H., Mackie J.E., Grant C.E., Almquist K.C., Stewart A.J., Kurz E.U., Duncan A.M.V., Deeley R.G., Duncan; A.M.V., Deeley R.G. Overexpression of a transporter gene in a multidrug-resistant human lung cancer line. Science. 258:1992;1650-1654
20. Borst P., Evers R., Kool M., Wijnholds J. A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst. 92:2000;1295-1302
21. Jedlitschky G., Leier I., Bucholz U., Barnouin K., Kurz G., Keppler D. Transport of glutathione, glucuronate and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res. 56:1996;988-994
22. Leslie E.M., Deeley R.G., Cole S.P.C. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology. 167:2001;3-23
23. Minier C., Eufemia N., Epel D. The multi-xenobiotic resistance phenotype as a tool to biomonitor the environment. Biomarkers. 4:1999;442-454
24. Smital T., Sauerborn R., Hackenberger B.K. Inducibility of the P-glycoprotein transport activity in the marine mussel Mytilus galloprovincialis and the freshwater mussel Dreissena polymorpha. Aquat. Toxicol. 65:2003;443-465
25. Miller D.S., Masereeuw R., Henson J., Karnaky K. Excretory transport of xenobiotics by dogfish shark rectal gland tubules. Am. J. Physiol. (Reg. Int. Comp. Physiol.). 275:1998;R697-R705
26. Miller D.S. Confocal imaging of xenobiotic transport across the blood-brain barrier. J. Exp. Zool. 300A:2003;84-90
27. R. Sauerborn, D. Stupin Polančec, R. Žaja, T. Smital, Identification of the multidrug resistance-associated protein (MRP) related gene in the red mullet (Mullus barbatus). Mar. Environ. Res. 56 (2004) 199-204.
28. Holland-Toomey B., Epel D. Multixenobiotic resistance in Urechis embrios: Protection from environmental toxins. Biol. Bull. 185:1993;355-386
29. Toomey B.H., Kaufman M.R., Epel D. Marine bacteria produce compounds that modulate multixenobiotic transport activity in Urechis caupo embryos. Mar. Environ. Res. 42:1996;393-397
30. Ahel I., Tepić N., Britvić S., Ahel M. Assessment of organic pollution in the Jakuševec landfill (Croatia) by biomarker and chemical methods. Fres. Environ. Bull. 9:2000;726-733
31. Barnes K.M., Dickstein B., Cutler G.B., Fojo A.T., Bates S.E. Steroid transport, accumulation, and antagonism of P-glycoprotein in multidrug resistant cells. Biochemistry. 35:1996;4820-4827
32. Stein W.D. Kinetics of the multidrug transporter (P-glycoprotein) and its reversal. Physiol. Rev. 77:1997;545-590
33. Waldmann P., Pivčević B., Mueller W.E.G., Zahn R.K., Kurelec B. Increased genotoxicity of acetylaminofluorene by modulators of multixenobiotic resistance mechanism: studies with the freshwater clam Corbicula fluminea. Mutat. Res. 342:1993;113-123
34. Kurelec B., Krča S., Pivčević B., Ugarković D., Bachmann M., Imsiecke G., Mueller W.E.G. Expression of P-glycoprotein gene in marine sponges. Identification and characterization of the 125-kDa drug-binding glycoprotein. Carcinogenesis. 13:1992;69-76
35. Britvić S., Kurelec B. The effect of inhibitors of multixenobiotic resistance mechanism on the production of mutagens by Dreissena polymorpha in waters spiked with premutagens. Aquat. Toxicol. 47:1999;107-116
36. Heflich R.H., Neft R.E. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat. Res. 318:1994;73-114
37. Kurelec B. Exclusive activation of aromatic amines in the marine mussel Mytilus edulis by FAD-containing monooxigenase. Biochem. Biophys. Res. Commun. 127:1985;773-778
38. Britvić S., Kurelec B. Selective activation of carcinogenic aromatic amines to bacterial mutagens in the marine mussel Mytilus galloprovincialis. Comp. Biochem. Physiol. 85C:1986;111-114
39. I. McFadzen, N. Eufemia, C. Heather, D. Epel, M. Moore, D. Lowe, Multidrug resistance in the embryos and larvae of the mussel, Mytilus edulis, in: A.A. Elskus, W.K. Vogelbein, S.M. Laughlin, A.S. Kane (Eds.), PRIMO 10 (Pollutant Responses in Marine Organisms), Williamsburg, VA, pp. 93.
40. Schröder H.C., Badria F.A., Ayyad S.N., Batel R., Wiens M., Hassanein H.M.A., Kurelec B., Müller W.E.G. Inhibitory effects of extracts from the marine alga Caulerpa taxifolia and of toxin from Caulerpa racemosa on multixenobiotic resistance in the marine sponge Geodia cydonium. Environ. Toxicol. Pharmacol. 5:1998;119-126
41. Smital T., Pivčević B., Kurelec B. Reversal of multidrug reistance by extract from the marine alga Caulerpa taxifolia. Period. Biol. 98:1996;1197-1203
42. Schinkel A.H., Smit J.J.M., Vantellingen O., Beijnen J.H., Wagenaar E., Vandeemter L., Mol C.A.A.M., Vandervalk M.A., Robanusmaandag E.C., Teriele H.P.J., Berns A.J.M., Borst P. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain marrier and to increased sensitivity to drugs. Cell. 77:1994;491-502
43. Lanning C.L., Fine R.L., Corcoran J.J., Ayad H.M., Rose R.L., Aboudonia M.B. Tobacco budworm P-glycoprotein - biochemical characterization and its involvement in pesticide resistance. Biochim. Biophys. Acta Gen. Sub. 1291:1996;155-162
44. Lanning C.L., Ayad H.M., Aboudonia M.B. P-glycoprotein involvement in cuticular penetration of [C-14]thiodicarb in resistant tobacco budworms. Toxicol. Lett. 85:1997;127-133
45. Galgani F., Cornwall R., Toomey B.H., Epel D. Interaction of environmental xenobiotics with a multixenobiotic defense mechanism in the bay mussel Mytilus galloprovincialis from the coast of California. Environ. Toxicol. Chem. 15:1996;325-331
46. Bain L.J., LeBlanc G.A. Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein. Toxicol. Appl. Pharmacol. 141:1996;288-298
47. Käfferlein H.U., Goen T., Angerer J.J. Musk xylene: analysis, occurrence, kinetics, and toxicology. Crit. Rev. Toxicol. 28:1998;431-476
48. Rimkus G.G., Wolf M. Polycyclic musk fragrances in human adipose tissue and human milk. Chemosphere. 33:1996;2033-2043
49. D. Epel, T. Smital, Multidrug-multixenobiotic transporters and their significance with respect to environmental levels of pharmaceuticals and personal care products, in: C.G. Daughton, T.L. Jones-Lepp (Eds.), Pharmaceuticals and Personal Care Products in the Environment. Scientific and Regulatory Issues, vol. 791, American Chemical Society, Washington, DC, 2001, pp. 244-263.
50. Luckenbach T., Corsi I., Epel D. Fatal attraction: synthetic musk fragrances compromise multixenobiotic defense systems in mussels. Mar. Environ. Res. 56:2004;215-219
51. D.G. Crosby, Environmental Toxicology and Chemistry, Oxford University Press, New York, NY, USA, 1998.
52. Hamdoun A.M., Griffin F.J., Cherr G.N. Tolerance to biodegraded crude oil in marine invertebrate embryos and larvae is associated with expression of a multixenbiotic resistance transporter. Aquat. Toxicol. 61:2002;127-140
53. Shelton M.E., Chapman P.J., Foss S.S., Fisher W.S. Degradation of weathered oil by mixed marine bacteria and the toxicity of accumulated water-soluble material to two marine crustacea. Arch. Environ. Contam. Toxicol. 36:1999;13-20
54. R.B. Spies, Biological effects of petroleum hydrocarbons: assessments from the field and microcosms, in: N. Rabalais, D. Boesch (Eds.), Long-Term Environmental Effects of Offshore Oil and Gas Development, Elsevier Applied Science, 1987, pp. 411-468.
55. Essodaïgui M., Broxterman H.J., Garnier-Suillerot A. Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated ba the multidrug resistance protein and P-glycoprotein. Biochemistry. 37:1998;2243-2250
56. Hooiveld G.J.E.J., van Montfoort J.E., Meier D.K.F., Müller M. Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport. Eur. J. Pharm. Sci. 12:2001;525-543
57. Sarkadi B., Price E.M., Bouchers R.C., Germann U.A., Scarborough G.A. Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. J. Biol. Chem. 267:1992;4854-4858
58. Hollo Z., Homolya L., Davis C.W., Sarkadi B. Calcein accumulation as a fluorometric functional assay of the multidrug transporter. Biochim. Biophys. Acta. 1191:1994;384-388
59. Weiss B. A risk assessment perspective of the neurobehavioral toxicity of endocrine disruptors. Toxicol. Ind. Health. 14:1998;341-359
60. Kurelec B. The genotoxic disease syndrome. Mar. Environ. Res. 35:1993;341-348