메뉴 건너뛰기




Volumn 10, Issue 11, 2010, Pages 1147-1156

Cyclin e and histone H3 levels are regulated by 5-fluorouracil in a DNA mismatch repair-dependent manner

Author keywords

5 fluorouracil; Cancer treatment; Colorectal cancer; Cyclin E; DNA mismatch repair; Histone H3; Microsatellite instability

Indexed keywords

CYCLIN B1; CYCLIN B2; CYCLIN E; FLUOROURACIL; HISTONE H2A; HISTONE H2B; HISTONE H3; MISMATCH REPAIR PROTEIN PMS2; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE P60; PROTEIN P53;

EID: 78649891006     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.11.13447     Document Type: Article
Times cited : (12)

References (48)
  • 1
    • 0024397951 scopus 로고
    • Surgical adjuvant therapy of large-bowel carcinoma: An evaluation of levamisole and the combination of levamisole and fluorouracil
    • The North Central Cancer Treatment Group and the Mayo
    • Laurie JA, Moertel CG, Fleming TR, Wieand HS, Leigh JE, Rubin J, et al. Surgical adjuvant therapy of large-bowel carcinoma: an evaluation of levamisole and the combination of levamisole and fluorouracil. The North Central Cancer Treatment Group and the Mayo. Clinic J Clin Oncol 1989; 7:1447-56.
    • (1989) Clinic J Clin Oncol , vol.7 , pp. 1447-1456
    • Laurie, J.A.1    Moertel, C.G.2    Fleming, T.R.3    Wieand, H.S.4    Leigh, J.E.5    Rubin, J.6
  • 3
    • 0028956045 scopus 로고
    • Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
    • Moertel CG, Fleming TR, Macdonald JS, Haller DG, Laurie JA, Tangen CM, et al. Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann Intern Med 1995; 122:321-6.
    • (1995) Ann Intern Med , vol.122 , pp. 321-326
    • Moertel, C.G.1    Fleming, T.R.2    Macdonald, J.S.3    Haller, D.G.4    Laurie, J.A.5    Tangen, C.M.6
  • 5
    • 0344109583 scopus 로고    scopus 로고
    • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
    • Cancer Meta-Analysis Groups
    • Cancer Meta-Analysis Groups. Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol 1998; 16:301-8.
    • (1998) J Clin Oncol , vol.16 , pp. 301-308
  • 7
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • Ribic CM, Sargent DJ, Moore MJ, Thibodeau SN, French AJ, Goldberg RM, et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 2003; 349:247-57.
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3    Thibodeau, S.N.4    French, A.J.5    Goldberg, R.M.6
  • 9
    • 0029659046 scopus 로고    scopus 로고
    • HMutS-beta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
    • Palombo F, Iaccarino I, Nakajima E, Ikejima M, Shimada T, Jiricny J. hMutS-beta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr Biol 1996; 6:1181-4.
    • (1996) Curr Biol , vol.6 , pp. 1181-1184
    • Palombo, F.1    Iaccarino, I.2    Nakajima, E.3    Ikejima, M.4    Shimada, T.5    Jiricny, J.6
  • 10
    • 33750083332 scopus 로고    scopus 로고
    • Mechanisms in eukaryotic mismatch repair
    • Modrich P. Mechanisms in eukaryotic mismatch repair. J Biol Chem 2006; 281:30305-9.
    • (2006) J Biol Chem , vol.281 , pp. 30305-30309
    • Modrich, P.1
  • 11
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady WM, Carethers JM. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 2008; 135:1079-99.
    • (2008) Gastroenterology , vol.135 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 12
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • DOI 10.1016/0092-8674(93)90546-3
    • Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993; 75:1027-38. (Pubitemid 24014559)
    • (1993) Cell , vol.75 , Issue.5 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.S.3    Copeland, N.G.4    Jenkins, N.A.5    Garber, J.6    Kane, M.7    Kolodner, R.8
  • 13
    • 0030870631 scopus 로고    scopus 로고
    • Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred
    • Akiyama Y, Sato H, Yamada T, Nagasaki H, Tsuchiya A, Abe R, et al. Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res 1997; 57:3920-3.
    • (1997) Cancer Res , vol.57 , pp. 3920-3923
    • Akiyama, Y.1    Sato, H.2    Yamada, T.3    Nagasaki, H.4    Tsuchiya, A.5    Abe, R.6
  • 16
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998; 95:6870-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6870-6875
    • Herman, J.G.1    Umar, A.2    Polyak, K.3    Graff, J.R.4    Ahuja, N.5    Issa, J.P.6
  • 18
    • 33646798052 scopus 로고    scopus 로고
    • Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer
    • Jover R, Zapater P, Castells A, Llor X, Andreu M, Cubiella J, et al. Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer. Gut 2006; 55:848-55.
    • (2006) Gut , vol.55 , pp. 848-855
    • Jover, R.1    Zapater, P.2    Castells, A.3    Llor, X.4    Andreu, M.5    Cubiella, J.6
  • 20
    • 9644270289 scopus 로고    scopus 로고
    • The mismatch repair complex hMutSalpha recognizes 5-fluorouracil-modified DNA: Implications for chemosensitivity and resistance
    • DOI 10.1053/j.gastro.2004.10.001, PII S0016508504018001
    • Tajima A, Hess MT, Cabrera BL, Kolodner RD, Carethers JM. The mismatch repair complex hMutS alpha recognizes 5-fluorouracil-modified DNA: implications for chemosensitivity and resistance. Gastroenterology 2004; 127:1678-84. (Pubitemid 39575846)
    • (2004) Gastroenterology , vol.127 , Issue.6 , pp. 1678-1684
    • Tajima, A.1    Hess, M.T.2    Cabrera, B.L.3    Kolodner, R.D.4    Carethers, J.M.5
  • 24
    • 0027292234 scopus 로고
    • An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
    • Kat A, Thilly WG, Fang WH, Longley MJ, Li GM, Modrich P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci USA 1993; 90:6424-8.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6424-6428
    • Kat, A.1    Thilly, W.G.2    Fang, W.H.3    Longley, M.J.4    Li, G.M.5    Modrich, P.6
  • 26
    • 1842715589 scopus 로고    scopus 로고
    • Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine
    • Hickman MJ, Samson LD. Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine. Mol Cell 2004; 14:105-16.
    • (2004) Mol Cell , vol.14 , pp. 105-116
    • Hickman, M.J.1    Samson, L.D.2
  • 28
    • 0025356873 scopus 로고
    • Phase I trial of 5-fluorouracil and dipyridamole administered by seventy-two-hour concurrent continuous infusion
    • Remick SC, Grem JL, Fischer PH, Tutsch KD, Alberti DB, Nieting LM, et al. Phase I trial of 5-fluorouracil and dipyridamole administered by seventy-two-hour concurrent continuous infusion. Cancer Res 1990; 50:2667-72.
    • (1990) Cancer Res , vol.50 , pp. 2667-2672
    • Remick, S.C.1    Grem, J.L.2    Fischer, P.H.3    Tutsch, K.D.4    Alberti, D.B.5    Nieting, L.M.6
  • 29
    • 0033402721 scopus 로고    scopus 로고
    • Mismatch repair, G(2)/M cell cycle arrest and lethality after DNA damage
    • Aquilina G, Crescenzi M, Bignami M. Mismatch repair, G(2)/M cell cycle arrest and lethality after DNA damage. Carcinogenesis 1999; 20:2317-26.
    • (1999) Carcinogenesis , vol.20 , pp. 2317-2326
    • Aquilina, G.1    Crescenzi, M.2    Bignami, M.3
  • 31
    • 0036133902 scopus 로고    scopus 로고
    • Upregulation of vitamin D3 upregulated protein 1 gene in response to 5-fluorouracil in colon carcinoma SW620
    • Takahashi Y, Nagata T, Ishii Y, Ikarashi M, Ishikawa K, Asai S. Upregulation of vitamin D3 upregulated protein 1 gene in response to 5-fluorouracil in colon carcinoma SW620. Oncol Rep 2002; 9:75-9.
    • (2002) Oncol Rep , vol.9 , pp. 75-79
    • Takahashi, Y.1    Nagata, T.2    Ishii, Y.3    Ikarashi, M.4    Ishikawa, K.5    Asai, S.6
  • 33
    • 0142219878 scopus 로고    scopus 로고
    • Molecular pharmacology of cancer therapy in human colorectal cancer by gene expression profiling
    • Clarke PA, George ML, Easdale S, Cunningham D, Swift RI, Hill ME, et al. Molecular pharmacology of cancer therapy in human colorectal cancer by gene expression profiling. Cancer Res 2003; 63:6855-63.
    • (2003) Cancer Res , vol.63 , pp. 6855-6863
    • Clarke, P.A.1    George, M.L.2    Easdale, S.3    Cunningham, D.4    Swift, R.I.5    Hill, M.E.6
  • 34
    • 2942625995 scopus 로고    scopus 로고
    • Comparison of gene expression in HCT116 treatment derivatives generated by two different 5-fluorouracil exposure protocols
    • De Angelis PM, Kravik KL, Tunheim SH, Haug T, Reichelt WH. Comparison of gene expression in HCT116 treatment derivatives generated by two different 5-fluorouracil exposure protocols. Mol Cancer 2004; 3:11.
    • (2004) Mol Cancer , vol.3 , pp. 11
    • De Angelis, P.M.1    Kravik, K.L.2    Tunheim, S.H.3    Haug, T.4    Reichelt, W.H.5
  • 35
    • 33745076752 scopus 로고    scopus 로고
    • Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: Three-gene expression model predicts clinical response
    • Matsuyama R, Togo S, Shimizu D, Momiyama N, Ishikawa T, Ichikawa Y, et al. Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response. Int J Cancer 2006; 119:406-13.
    • (2006) Int J Cancer , vol.119 , pp. 406-413
    • Matsuyama, R.1    Togo, S.2    Shimizu, D.3    Momiyama, N.4    Ishikawa, T.5    Ichikawa, Y.6
  • 36
    • 33646182010 scopus 로고    scopus 로고
    • Multilevel gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer
    • Xi Y, Nakajima G, Schmitz JC, Chu E, Ju J. Multilevel gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer. BMC Genomics 2006; 7:68.
    • (2006) BMC Genomics , vol.7 , pp. 68
    • Xi, Y.1    Nakajima, G.2    Schmitz, J.C.3    Chu, E.4    Ju, J.5
  • 37
    • 0033778049 scopus 로고    scopus 로고
    • Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
    • Hemminki A, Mecklin JP, Jarvinen H, Aaltonen LA, Joensuu H. Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology 2000; 119:921-8.
    • (2000) Gastroenterology , vol.119 , pp. 921-928
    • Hemminki, A.1    Mecklin, J.P.2    Jarvinen, H.3    Aaltonen, L.A.4    Joensuu, H.5
  • 38
    • 0033986545 scopus 로고    scopus 로고
    • P53 gene mutation, microsatellite instability and adjuvant chemotherapy: Impact on survival of 388 patients with Dukes' C colon carcinoma
    • Elsaleh H, Powell B, Soontrapornchai P, Joseph D, Goria F, Spry N, et al. p53 gene mutation, microsatellite instability and adjuvant chemotherapy: impact on survival of 388 patients with Dukes' C colon carcinoma. Oncology 2000; 58:52-9.
    • (2000) Oncology , vol.58 , pp. 52-59
    • Elsaleh, H.1    Powell, B.2    Soontrapornchai, P.3    Joseph, D.4    Goria, F.5    Spry, N.6
  • 39
    • 0034690610 scopus 로고    scopus 로고
    • Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
    • Elsaleh H, Joseph D, Grieu F, Zeps N, Spry N, Iacopetta B. Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer. Lancet 2000; 355:1745-50.
    • (2000) Lancet , vol.355 , pp. 1745-1750
    • Elsaleh, H.1    Joseph, D.2    Grieu, F.3    Zeps, N.4    Spry, N.5    Iacopetta, B.6
  • 40
    • 0035110959 scopus 로고    scopus 로고
    • Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: A novel target mechanism concept for pharmacokinetic modulating chemotherapy
    • Yoshikawa R, Kusunoki M, Yanagi H, Noda M, Furuyama JI, Yamamura T, et al. Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy. Cancer Res 2001; 61:1029-37.
    • (2001) Cancer Res , vol.61 , pp. 1029-1037
    • Yoshikawa, R.1    Kusunoki, M.2    Yanagi, H.3    Noda, M.4    Furuyama, J.I.5    Yamamura, T.6
  • 42
    • 34248592246 scopus 로고    scopus 로고
    • Celecoxib attenuates 5-fluorouracil-induced apoptosis in HCT-15 and HT-29 human colon cancer cells
    • Lim YJ, Rhee JC, Bae YM, Chun WJ. Celecoxib attenuates 5-fluorouracil-induced apoptosis in HCT-15 and HT-29 human colon cancer cells. World J Gastroenterol 2007; 13:1947-52.
    • (2007) World J Gastroenterol , vol.13 , pp. 1947-1952
    • Lim, Y.J.1    Rhee, J.C.2    Bae, Y.M.3    Chun, W.J.4
  • 43
    • 65649089859 scopus 로고    scopus 로고
    • 5-Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line
    • Matuo R, Sousa FG, Escargueil AE, Grivicich I, Garcia-Santos D, Chies JA, et al. 5-Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line. J Appl Toxicol 2009; 29:308-16.
    • (2009) J Appl Toxicol , vol.29 , pp. 308-316
    • Matuo, R.1    Sousa, F.G.2    Escargueil, A.E.3    Grivicich, I.4    Garcia-Santos, D.5    Chies, J.A.6
  • 47
    • 35848951163 scopus 로고    scopus 로고
    • Covalent modifications of histones during development and disease pathogenesis
    • DOI 10.1038/nsmb1337, PII NSMB1337
    • Bhaumik SR, Smith E, Shilatifard A. Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 2007; 14:1008-16. (Pubitemid 350060343)
    • (2007) Nature Structural and Molecular Biology , vol.14 , Issue.11 , pp. 1008-1016
    • Bhaumik, S.R.1    Smith, E.2    Shilatifard, A.3
  • 48
    • 0027936057 scopus 로고
    • Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
    • Koi M, Umar A, Chauhan DP, Cherian SP, Carethers JM, Kunkel TA, et al. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res 1994; 54:4308-12. (Pubitemid 24273140)
    • (1994) Cancer Research , vol.54 , Issue.16 , pp. 4308-4312
    • Koi, M.1    Umar, A.2    Chauhan, D.P.3    Cherian, S.P.4    Carethers, J.M.5    Kunkel, T.A.6    Boland, C.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.