The Sin3p PAH domains provide separate functions repressing meiotic gene transcription in Saccharomyces cerevisiae

Eukaryotic Cell

Volumn 9, Issue 12, 2010, Pages 1835-1844

  Mallory, Michael J ^a,c   Law, Michael J ^a   Buckingham, Lela E ^b   Strich, Randy ^a  

^a UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE; REPRESSOR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SIN3 PROTEIN, S CEREVISIAE;

ARTICLE; CHEMISTRY; CYTOLOGY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MEIOSIS; METABOLISM; PROMOTER REGION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE;

GENE EXPRESSION REGULATION, FUNGAL; HISTONE DEACETYLASES; MEIOSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 78649876751     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00143-10     Document Type: Article

References (45)

1. Arcangioli, B., and B. Lescure. 1985. Identification of proteins involved in the regulation of yeast iso-1-cytochrome C expression by oxygen. EMBO 4:2627-2633.
2. Ayer, D. E., Q. A. Lawrence, and R. N. Eisenman. 1995. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell 80:767-776.
3. Bowdish, K. S., and A. P. Mitchell. 1993. Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae. Mol. Cell. Biol. 13:2172-2181.
4. Braunstein, M., A. B. Rose, S. G. Holmes, C. D. Allis, and J. R. Broach. 1993. Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev. 7:592-604.
5. Buckingham, L. E., H.-T. Wang, R. T. Elder, R. M. McCarroll, M. R. Slater, and R. E. Esposito. 1990. Nucleotide sequence and promoter analysis of SPO13, a meiosis-specific gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U. S. A. 87:9406-9410.
6. Carrozza, M., L. Florens, S. Swanson, W. Shia, S. Anderson, J. Yates, M. Washburn, and J. Workman. 2005. Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim. Biophys. Acta 1731:77-87; discussion 75-76.
7. Chu, S., J. DeRisi, M. Eisen, J. Mulholland, D. Botstein, P. O. Brown, and I. Herskowitz. 1998. The transcriptional program of sporulation in budding yeast. Science 282:699-705.
8. Cooper, K. F., and R. Strich. 2002. Saccharomyces cerevisiae C-type cyclin UME3/SRB11 is required for efficient induction and execution of meiotic development. Eukaryot. Cell 1:67-76.
9. Gietz, R. D., and A. Sugino. 1988. Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base-pair restriction sites. Gene 74:527-534.
10. Goldmark, J. P., T. G. Fazzio, P. W. Estep, G. M. Church, and T. Tsukiyama. 2000. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell 103:423-433.
11. Hepworth, S. R., H. Friesen, and J. Segall. 1998. NDT80 and the meiotic recombination checkpoint regulate expression of middle sporulation-specific genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:5750-5761.
12. Honigberg, S. M., R. M. McCarroll, and R. E. Esposito. 1993. Regulatory mechanisms in meiosis. Curr. Opin. Cell Biol. 5:219-225.
13. Kadosh, D., and K. Struhl. 1997. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89:365-371.
14. Kassir, Y., D. Granot, and G. Simchen. 1988. IME1, a positive regulator of meiosis in S. cerevisiae. Cell 52:853-862.
15. Laherty, C. D., W.-M. Yang, J.-M. Sun, J. R. Davie, E. Seto, and R. N. Eisenman. 1997. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89:349-356.
16. Mallory, M. J., K. F. Cooper, and R. Strich. 2007. Meiosis-specific destruction of the Ume6p repressor by the Cdc20-directed APC/C. Mol. Cell 27: 951-961.
17. Mallory, M. J., and R. Strich. 2003. Ume1p represses meiotic gene transcription in S. cerevisiae through interaction with the histone deacetylase Rpd3p. J. Biol. Chem. 278:44727-44734.
18. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
19. Meluh, P. B., and D. Koshland. 1997. Budding yeast centromere composition and assembly as revealed by in vivo cross-linking. Genes Dev. 11:3401-3412.
20. Mitchell, A. P. 1994. Control of meiotic gene expression in Saccharomyces cerevisiae. Microbiol. Rev. 58:56-70.
21. Pak, J., and J. Segall. 2002. Regulation of the premiddle and middle phases of expression of the NDT80 gene during sporulation of Saccharomyces cerevisiae. Mol. Cell. Biol. 22:6417-6429.
22. Park, H.-O., and E. A. Craig. 1989. Positive and negative regulation of basal expression of a yeast HSP70 gene. Mol. Cell. Biol. 9:2025-2033.
23. Park, H. D., R. M. Luche, and T. G. Cooper. 1992. The yeast UME6 gene product is required for transcriptional repression mediated by the CAR1 URS1 repressor binding site. Nucleic Acids Res. 20:1909-1915.
24. Percival-Smith, A., and J. Segall. 1986. Characterization and mutational analysis of a cluster of three genes expressed preferentially during sporulation of Saccharomyces cerevisiae. Mol. Cell. Biol. 6:2443-2451.
25. Primig, M., R. M. Williams, E. A. Winzeler, G. G. Tevzadze, A. R. Conway, S. Y. Hwang, R. W. Davis, and R. E. Esposito. 2000. The core meiotic transcriptome in budding yeasts. Nat. Genet. 26:415-423.
26. Rothstein, R. 1991. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast, p. 281-301. In J. N. Abelson and M. I. Simon (ed.), Methods in enzymology, vol. 194. Academic Press Inc., San Diego, CA.
27. Russell, D. W., R. Jensen, M. J. Zoller, J. Burke, B. Errede, M. Smith, and I. Herskowitz. 1986. Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region. Mol. Cell. Biol. 6:4281-4294.
28. Schreiber-Agus, N., L. Chin, K. Chen, R. Torres, G. Rao, P. Guida, A. I. Skoultchi, and R. A. DePiho. 1995. An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN33. Cell 80:777-786.
29. Silverstein, R. A., and K. Ekwall. 2005. Sin3: a flexible regulator of global gene expression and genome stability. Curr. Genet. 47:1-17.
30. Strich, R., M. R. Slater, and R. E. Esposito. 1989. Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast. Proc. Natl. Acad. Sci. U. S. A. 86:10018-10022.
31. Strich, R., R. T. Surosky, C. Steber, E. Dubois, F. Messenguy, and R. E. Esposito. 1994. UME6 is a key regulator of nitrogen repression and meiotic development. Genes Dev. 8:796-810.
32. Sumrada, R. A., and T. G. Cooper. 1985. Point mutation generates constitutive expression of an inducible eukaryotic gene. Proc. Natl. Acad. Sci. U. S. A. 82:643-647.
33. Surosky, R. T., R. Strich, and R. E. Esposito. 1994. The yeast UME5 gene regulates the stability of meiotic mRNAs in response to glucose. Mol. Cell. Biol. 14:3446-3458.
34. Szent-Gyorgyi, C. 1995. A bipartite operator interacts with a heat shock element to mediate early meiotic induction of Saccharomyces cerevisiae HSP82. Mol. Cell. Biol. 15:6754-6769.
35. van Oevelen, C., J. Wang, P. Asp, Q. Yan, W. G. Kaelin, Jr, Y. Kluger, and B. D. Dynlacht. 2008. A role for mammalian Sin3 in permanent gene silencing. Mol. Cell 32:359-370.
36. Vermeulen, M., W. Walter, X. Le Guezennec, J. Kim, R. S. Edayathumangalam, E. Lasonder, K. Luger, R. G. Roeder, C. Logie, S. L. Berger, and H. G. Stunnenberg. 2006. A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Mol. Cell. Biol. 26:5226-5236.
37. Vershon, A. K., N. M. Hollingsworth, and A. D. Johnson. 1992. Meiotic induction of the yeast HOP1 gene is controlled by positive and negative regulatory sites. Mol. Cell. Biol. 12:3706-3714.
38. Vidal, M., A. M. Buckley, C. Yohn, D. J. Hoeppner, and R. F. Gaber. 1995. Identification of essential nucleotides in an upstream repressing sequence of Saccharomyces cerevisiae by selection for increased expression of TRK2. Proc. Natl. Acad. Sci. U. S. A. 92:2370-2374.
39. Vidal, M., and R. F. Gaber. 1991. RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:6317-6327.
40. Vidal, M., R. Strich, R. E. Esposito, and R. F. Gaber. 1991. RPD1 (SIN3/ UME4) is required for maximal activation and repression of diverse yeast genes. Mol. Cell. Biol. 11:6306-6316.
41. Vogelauer, M., J. Wu, N. Suka, and M. Grunstein. 2000. Global histone acetylation and deacetylation in yeast. Nature 408:495-498.
42. Wang, H., I. Clark, P. R. Nicholson, I. Herskowitz, and D. J. Stillman. 1990. The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs. Mol. Cell. Biol. 10:5927-5936.
43. Wang, H., and D. J. Stillman. 1993. Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein. Mol. Cell. Biol. 13:1804-1815.
44. Washburn, B. K., and R. E. Esposito. 2001. Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast. Mol. Cell. Biol. 21:2057-2069.
45. Yang, X., F. Zhang, and J. E. Kudlow. 2002. Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein OGlcNAcylation to transcriptional repression. Cell 110:69-80.