Tumor necrosis factor causes persistent sensitization of joint nociceptors to mechanical stimuli in rats

Arthritis Care and Research

Volumn 62, Issue 12, 2010, Pages 3806-3814

  Richter, Frank ^a   Natura, Gabriel ^a   Löser, Stefan ^a   Schmidt, Katarina ^a   Viisanen, Hanna ^b,c   Schaible, Hans Georg ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; DICLOFENAC; ETANERCEPT; INDOMETACIN; TUMOR NECROSIS FACTOR; PROSTAGLANDIN SYNTHASE; PROTEIN INHIBITOR; SYNAPTOPHYSIN;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; HYPERALGESIA; IN VITRO STUDY; MALE; MECHANICAL STIMULATION; NERVE CELL EXCITABILITY; NERVE FIBER; NOCICEPTION; NONHUMAN; PATCH CLAMP; RAT; SENSITIZATION; SIGNAL TRANSDUCTION; SPINAL GANGLION; ALPHA NERVE FIBER; ARTHRITIS; GAMMA NERVE FIBER; JOINT FUNCTION; KNEE; NERVE CELL; NERVE FIBER C; NOCICEPTIVE RECEPTOR; NOCICEPTIVE STIMULATION; PRIORITY JOURNAL; STIMULUS; TUMOR NECROSIS;

ACTION POTENTIALS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; DICLOFENAC; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIA, SPINAL; IMMUNOGLOBULIN G; INJECTIONS, INTRA-ARTICULAR; KNEE JOINT; MALE; MODELS, ANIMAL; NOCICEPTORS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, TUMOR NECROSIS FACTOR; STRESS, MECHANICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78649866369     PISSN: 21514658     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27715     Document Type: Article

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