Impaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker rat

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 299, Issue 6, 2010, Pages

  Katta, Anjaiah ^a,b   Kundla, Sudarsanam ^b   Kakarla, Sunil K ^a,b   Wu, Miaozong ^a,b   Fannin, Jacqueline ^a   Paturi, Satyanarayana ^b   Liu, Hua ^a,b,c   Addagarla, Hari S ^b   Blough, Eric R ^a,b  

^a MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MARSHALL UNIVERSITY   (United States)

^c SOUTHEAST UNIVERSITY   (China)

Author keywords

Eukaryotic elongation factor 2; Eukaryotic initiation factor 4E binding protein 1; Myogenin; Ribosomal protein S6

Indexed keywords

ELONGATION FACTOR 2; MAMMALIAN TARGET OF RAPAMYCIN; MYOGENIN; PROTEIN KINASE B; PROTEIN S6;

ANIMAL EXPERIMENT; ARTICLE; INSULIN RESISTANCE; MUSCLE ATROPHY; MUSCLE HYPERTROPHY; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE; SOLEUS MUSCLE; ZUCKER RAT;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERTROPHY; INSULIN; INSULIN RESISTANCE; MUSCLE, SKELETAL; OBESITY; RATS; RATS, ZUCKER; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 78649845396     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00229.2010     Document Type: Article

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