Human cardiospheres are a source of stem cells with cardiomyogenic potential

Stem Cells

Volumn 28, Issue 5, 2010, Pages 903-904

  Davis, Darryl R ^a   Smith, Rachel Ruckdeschel ^a   Marbán, Eduardo ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CULTURE; CYTOPLASM; HEART DEVELOPMENT; HEART FUNCTION; HUMAN; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; NONHUMAN; SMOOTH MUSCLE FIBER; STEM CELL; ANTIGEN EXPRESSION; CARDIOSPHERE; CELL DIFFERENTIATION; CELL LABELING; CELL TRANSPLANTATION; CONTROLLED STUDY; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE CELL; HUMAN CELL; PARACRINE SIGNALING; PROTEIN EXPRESSION; SEVERE COMBINED IMMUNODEFICIENCY;

ADULT STEM CELLS; ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; GRAFT SURVIVAL; HUMANS; MICE; MICE, SCID; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; REGENERATION; SPHEROIDS, CELLULAR; STEM CELL TRANSPLANTATION;

ALPHA SMOOTH MUSCLE ACTIN; BETA GALACTOSIDASE; CELL NUCLEUS ANTIGEN; CONNEXIN 43; GREEN FLUORESCENT PROTEIN; TROPONIN I; VON WILLEBRAND FACTOR;

EID: 77952242273     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.413     Document Type: Article

References (13)

1. Smith RR, Barile L, Cho HC et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 2007;115:896-908. (Pubitemid 46294730)
2. Davis DR, Kizana E, Terrovitis J et al. Cells cultured directly from heart biopsies express stem cell markers and improve function after myocardial infarction [abstract]. Circ Res 2008;103:1493-1501.
3. Bearzi C, Rota M, Hosoda T et al. Human cardiac stem cells. Proc Natl Acad Sci USA 2007;104:14068-14073.
4. Tang YL, Shen L, Qian K et al. A novel two-step procedure to expand cardiac Sca-1+ cells clonally. Biochem Biophys Res Commun 2007;359:877-883. (Pubitemid 46946901)
5. Ott HC, Matthiesen TS, Brechtken J et al. The adult human heart as a source for stem cells: Repair strategies with embryonic-like progenitor cells. Nat Clin Pract Cardiovasc Med 2007;4(Suppl 1):S27-S39. (Pubitemid 46151903)
6. Messina E, de Angelis L, Frati G et al. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 2004;95:911-921. (Pubitemid 39435006)
7. Johnston PV, Sasano T, Mills K et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 2009;120:1075-1083,7.
8. Andersen DC, Andersen P, Schneider M et al. Murine " cardiospheres" are not a source of stem cells with cardiomyogenic potential. Stem Cells 2009;27:1571-1581.
9. Smith RR, Chimenti I, Marban E. Unselected human cardiosphere-derived cells are functionally superior to c-kit- or CD90-purified cardiosphere-derived cells [abstract]. Circulation 2008;118, S-420.
10. Terrovitis J, Lautamäki R, Bonios M et al. Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery. J Am Coll Cardiol 2009;54:1619-1626.
11. Chimenti I, Smith RR, Li TS et al. Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res 2010;106:971-980.
12. Davis DR, Zhang Y, Smith RR et al. Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PLOS One 2009;4:e7195.
13. CArdiosphere-Derived aUtologous Stem CElls to Reverse ventricUlar dySfunction (CADUCEUS). 2009.