Pronounced virus-dependent activation drives exhaustion but sustains IFN-γ transcript levels

Journal of Immunology

Volumn 185, Issue 6, 2010, Pages 3643-3651

  Mackerness, Kathryn J ^a,d   Cox, Maureen A ^a   Lilly, Lauren M ^a   Weaver, Casey T ^b   Harrington, Laurie E ^c   Zajac, Allan J ^a  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d Immune Targeting Systems   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL POPULATION; CELLULAR IMMUNITY; CHRONIC LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; LYMPHOCYTOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VIRUS INFECTION;

ACUTE DISEASE; ANIMALS; ANTIGENS, THY-1; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; CHRONIC DISEASE; GENE KNOCK-IN TECHNIQUES; GENE SILENCING; GENES, REPORTER; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; STEM CELLS; TRANSCRIPTION, GENETIC; UP-REGULATION; VIRUS ACTIVATION;

EID: 78649822985     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000841     Document Type: Article

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