Allosteric activation mechanism of the mycobacterium tuberculosis receptor Ser/Thr protein Kinase, PknB

Structure

Volumn 18, Issue 12, 2010, Pages 1667-1677

  Lombana, T Noelle ^a,c   Echols, Nathaniel ^a,d   Good, Matthew C ^a,e   Thomsen, Nathan D ^a   Ng, Ho Leung ^a,f   Greenstein, Andrew E ^a,g   Falick, Arnold M ^b   King, David S ^b   Alber, Tom ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Gilead Sciences ^*  (United States)

^g GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE B;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; CATALYTIC DOMAIN; ENZYME ACTIVATION; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN-SERINE-THREONINE KINASES;

BACTERIA (MICROORGANISMS); EUKARYOTA; MYCOBACTERIUM TUBERCULOSIS;

EID: 78649790931     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2010.09.019     Document Type: Article

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