A Conserved Dimer and Global Conformational Changes in the Structure of apo-PknE Ser/Thr Protein Kinase from Mycobacterium tuberculosis

Journal of Molecular Biology

Volumn 360, Issue 2, 2006, Pages 409-420

  Gay, Laurie M ^a   Ng, Ho Leung ^a   Alber, Tom ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

allosteric regulation; bacterial phosphosignaling; DFG motif; kinase activation; PKR

Indexed keywords

ADENOSINE TRIPHOSPHATE; APOLIPOPROTEIN; BACTERIAL PROTEIN; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; REGULATORY MECHANISM;

EUKARYOTA; MYCOBACTERIUM TUBERCULOSIS;

EID: 33745253917     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.05.015     Document Type: Article

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