Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C

Structure

Volumn 18, Issue 12, 2010, Pages 1642-1653

  Escobar Cabrera, Eric ^a,b   Lau, Desmond K W ^a,b   Giovinazzi, Serena ^c   Ishov, Alexander M ^c,d   McIntosh, Lawrence P ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF FLORIDA   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DAXX PROTEIN; PROTEIN MDM2; PROTEIN P53; PROTEIN RASSF1C; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BINDING SITES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTANT PROTEINS; NUCLEAR PROTEINS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE DELETION; TUMOR SUPPRESSOR PROTEINS;

EID: 78649773554     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2010.09.016     Document Type: Article

References (58)

1. A. Bax, G. Kontaxis, and N. Tjandra Dipolar couplings in macromolecular structure determination Methods Enzymol 339 2001 127 174
2. 15N NMR relaxation data of globular proteins using hydrodynamic calculations with HYDRONMR J. Biomol. NMR 23 2002 139 150
3. V. Booth, C.M. Koth, A.M. Edwards, and C.H. Arrowsmith Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70 J. Biol. Chem. 275 2000 31266 31268
4. K. Brubaker, S.M. Cowley, K. Huang, L. Loo, G.S. Yochum, D.E. Ayer, R.N. Eisenman, and I. Radhakrishnan Solution structure of the interacting domains of the Mad-Sin3 complex: implications for recruitment of a chromatin-modifying complex Cell 103 2000 655 665
5. R. Candau, D.M. Scolnick, P. Darpino, C.Y. Ying, T.D. Halazonetis, and S.L. Berger Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity Oncogene 15 1997 807 816
6. C.C. Chang, D.Y. Lin, H.I. Fang, R.H. Chen, and H.M. Shih Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4 J. Biol. Chem. 280 2005 10164 10173
7. J.J. Chou, S. Gaemers, B. Howder, J.M. Louis, and A. Bax A simple apparatus for generating stretched polyacrylamide gels, yielding uniform alignment of proteins and detergent micelles J. Biomol. NMR 21 2001 377 382
8. G. Cornilescu, F. Delaglio, and A. Bax Protein backbone angle restraints from searching a database for chemical shift and sequence homology J. Biomol. NMR 13 1999 289 302
9. R. Dawson, L. Muller, A. Dehner, C. Klein, H. Kessler, and J. Buchner The N-terminal domain of p53 is natively unfolded J. Mol. Biol. 332 2003 1131 1141
10. W.L. DeLano Use of PYMOL as a communications tool for molecular science Abstracts of Papers of the American Chemical Society 228 2004 U313 U314
11. P. Dosset, J.C. Hus, M. Blackledge, and D. Marion Efficient analysis of macromolecular rotational diffusion from heteronuclear relaxation data J. Biomol. NMR 16 2000 23 28
12. P. Drane, K. Ouararhni, A. Depaux, M. Shuaib, and A. Hamiche The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3 Genes Dev. 24 2010 1253 1265
13. J.A. Ecsedy, J.S. Michaelson, and P. Leder Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity Mol. Cell. Biol. 23 2003 950 960
14. S.W. Englander, and N.R. Kallenbach Hydrogen-exchange and structural dynamics of proteins and nucleic-acids Q. Rev. Biophys. 16 1983 521 655
15. N.A. Farrow, R. Muhandiram, A.U. Singer, S.M. Pascal, C.M. Kay, G. Gish, S.E. Shoelson, T. Pawson, J.D. Formankay, and L.E. Kay Backbone dynamics of a free and a phosphopeptide-complexed Src Homology-2 domain studied by N-15 NMR relaxation Biochemistry 33 1994 5984 6003
16. J.C. Ferreon, C.W. Lee, M. Arai, M.A. Martinez-Yamout, H.J. Dyson, and P.E. Wright Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2 Proc. Natl. Acad. Sci. USA 106 2009 6591 6596
17. A.D. Goldberg, L.A. Banaszynski, K.M. Noh, P.W. Lewis, S.J. Elsaesser, S. Stadler, S. Dewell, M. Law, X. Guo, and X. Li Distinct factors control histone variant H3.3 localization at specific genomic regions Cell 140 2010 678 691
18. M. Gostissa, M. Morelli, F. Mantovani, E. Guida, S. Piazza, L. Collavin, C. Brancolini, C. Schneider, and G. Del Sal The transcriptional repressor hDaxx potentiates p53-dependent apoptosis J. Biol. Chem. 279 2004 48013 48023
19. M. Habeck, W. Rieping, J.P. Linge, and M. Nilges NOE assignment with ARIA 2.0: the nuts and bolts Methods Mol. Biol. 278 2004 379 402
20. A.D. Hollenbach, J.E. Sublett, C.J. McPherson, and G. Grosveld The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx EMBO J. 18 1999 3702 3711
21. A.D. Hollenbach, C.J. McPherson, E.J. Mientjes, R. Iyengar, and G. Grosveld Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek J. Cell Sci. 115 2002 3319 3330
22. A.M. Ishov, A.G. Sotnikov, D. Negorev, O.V. Vladimirova, N. Neff, T. Kamitani, E.T.H. Yeh, J.F. Strauss, and G.G. Maul PML is critical for ND10 formation and recruits the PML-interacting protein Daxx to this nuclear structure when modified by SUMO-1 J. Cell Biol. 147 1999 221 233
23. P.E. Johnson, P. Tomme, M.D. Joshi, and L.P. McIntosh Interaction of soluble cellooligosaccharides with the N-terminal cellulose-binding domain of Cellulomonas fimi CenC 2. NMR and ultraviolet absorption spectroscopy Biochemistry 35 1996 13895 13906 (Pubitemid 26374460)
24. Y.S. Jung, H.Y. Kim, J. Kim, M.G. Lee, J. Pouyssegur, and E. Kim Physical interactions and functional coupling between Daxx and sodium hydrogen exchanger 1 in ischemic cell death J. Biol. Chem. 283 2008 1018 1025
25. P. Juo, C.J. Kuo, J. Yuan, and J. Blenis Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade Curr. Biol. 8 1998 1001 1008
26. L. Kaustov, G.S. Yi, A. Ayed, E. Bochkareva, A. Bochkarev, and C.H. Arrowsmith p53 transcriptional activation domain: a molecular chameleon? Cell Cycle 5 2006 489 494
27. D.E. Kim, D. Chivian, and D. Baker Protein structure prediction and analysis using the Robetta server Nucleic Acids Res. 32 2004 W526 W531
28. D. Kitagawa, H. Kajiho, T. Negishi, S. Ura, T. Watanabe, T. Wada, H. Ichijo, T. Katada, and H. Nishina Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activation EMBO J. 25 2006 3286 3297
29. R. Koradi, M. Billeter, and K. Wüthrich MOLMOL: a program for display and analysis of macromolecular structures J. Mol. Graph. 14 1996 51 55 29-32
30. P.H. Kussie, S. Gorina, V. Marechal, B. Elenbaas, J. Moreau, A.J. Levine, and N.P. Pavletich Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain Science 274 1996 948 953 (Pubitemid 26398409)
31. D.Y. Lin, Y.S. Huang, J.C. Jeng, H.Y. Kuo, C.C. Chang, T.T. Chao, C.C. Ho, Y.C. Chen, T.P. Lin, and H.I. Fang Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors Mol. Cell 24 2006 341 354
32. Lindsay, C.R. (2008). Daxx and Rassf1 define a novel mitotic stress checkpoint that is critical for cellular taxol response. Ph.D. Thesis, University of Florida.
33. C.R. Lindsay, V.M. Morozov, and A.M. Ishov PML NBs (ND10) and Daxx: from nuclear structure to protein function Front. Biosci. 13 2008 7132 7142
34. C.R. Lindsay, S. Giovinazzi, and A.M. Ishov Daxx is a predominately nuclear protein that does not translocate to the cytoplasm in response to cell stress Cell Cycle 8 2009 1544 1551
35. M.S. Lindstrom, A. Jin, C. Deisenroth, G. White Wolf, and Y. Zhang Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation Mol. Cell. Biol. 27 2007 1056 1068
36. M.S. Macauley, W.J. Errington, M. Scharpf, C.D. Mackereth, A.G. Blaszczak, B.J. Graves, and L.P. McIntosh Beads-on-a-string, characterization of ETS-1 sumoylated within its flexible N-terminal sequence J. Biol. Chem. 281 2006 4164 4172
37. V.M. Morozov, N.A. Massoll, O.V. Vladimirova, G.G. Maul, and A.M. Ishov Regulation of c-met expression by transcription repressor Daxx Oncogene 27 2008 2177 2186
38. R. Muromoto, K. Nakao, T. Watanabe, N. Sato, Y. Sekine, K. Sugiyama, K. Oritani, K. Shimoda, and T. Matsuda Physical and functional interactions between Daxx and STAT3 Oncogene 25 2006 2131 2136
39. A.F. Pluta, W.C. Earnshaw, and I.G. Goldberg Interphase-specific association of intrinsic centromere protein CENP-C with hDaxx, a death domain-binding protein implicated in Fas-mediated cell death J. Cell Sci. 111 1998 2029 2041
40. S.R. Presnell, and F.E. Cohen Topological distribution of four-alpha-helix bundles Proc. Natl. Acad. Sci. USA 86 1989 6592 6596
41. L.A. Puto, and J.C. Reed Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation Genes Dev. 22 2008 998 1010
42. S.C. Sahu, K.A. Swanson, R.S. Kang, K. Huang, K. Brubaker, K. Ratcliff, and I. Radhakrishnan Conserved themes in target recognition by the PAH1 and PAH2 domains of the Sin3 transcriptional corepressor J. Mol. Biol. 375 2008 1444 1456
43. P. Salomoni, and A.F. Khelifi Daxx: death or survival protein? Trends Cell Biol. 16 2006 97 104
44. A. Santiago, A.C. Godsey, J. Hossain, L.Y. Zhao, and D. Liao Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions Cell Cycle 8 2009 76 87
45. H.M. Shih, C.C. Chang, H.Y. Kuo, and D.Y. Lin Daxx mediates SUMO-dependent transcriptional control and subnuclear compartmentalization Biochem. Soc. Trans. 35 2007 1397 1400
46. J.J. Song, and Y.J. Lee Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization J. Biol. Chem. 278 2003 47245 47252
47. M.S. Song, S.J. Song, S.Y. Kim, H.J. Oh, and D.S. Lim The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex EMBO J. 27 2008 1863 1874
48. C.A. Spronk, M. Tessari, A.M. Kaan, J.F. Jansen, M. Vermeulen, H.G. Stunnenberg, and G.W. Vuister The Mad1-Sin3B interaction involves a novel helical fold Nat. Struct. Biol. 7 2000 1100 1104
49. J. Tang, L.K. Qu, J. Zhang, W. Wang, J.S. Michaelson, Y.Y. Degenhardt, W.S. El-Deiry, and X. Yang Critical role for Daxx in regulating Mdm2 Nat. Cell Biol. 8 2006 855 862
50. S. Torii, D.A. Egan, R.A. Evans, and J.C. Reed Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs) EMBO J. 18 1999 6037 6049
51. H. van Ingen, M.A. Baltussen, J. Aelen, and G.W. Vuister Role of structural and dynamical plasticity in Sin3: the free PAH2 domain is a folded module in mSin3B J. Mol. Biol. 358 2006 485 497
52. H. Wang, I. Clark, P.R. Nicholson, I. Herskowitz, and D.J. Stillman The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs Mol. Cell. Biol. 10 1990 5927 5936
53. X. Yang, R. Khosravi-Far, H.Y. Chang, and D. Baltimore Daxx, a novel Fas-binding protein that activates JNK and apoptosis Cell 89 1997 1067 1076
54. P.L. Yeung, L.Y. Chen, S.C. Tsai, A. Zhang, and J.D. Chen Daxx contains two nuclear localization signals and interacts with importin alpha 3 J. Cell. Biochem. 103 2008 456 470
55. G.W. Yu, M.D. Allen, A. Andreeva, A.R. Fersht, and M. Bycroft Solution structure of the C4 zinc finger domain of HDM2 Protein Sci. 15 2006 384 389
56. J. Zhang, D. Cado, A. Chen, N.H. Kabra, and A. Winoto Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1 Nature 392 1998 296 300
57. C. Zwahlen, P. Legault, S.J.F. Vincent, J. Greenblatt, R. Konrat, and L.E. Kay Methods for measurement of intermolecular NOEs by multinuclear NMR spectroscopy: Application to a bacteriophage lambda N-peptide/boxB RNA complex J. Am. Chem. Soc. 119 1997 6711 6721
58. C. Zwahlen, K.H. Gardner, S.P. Sarma, D.A. Horita, R.A. Byrd, and L.E. Kay An NMR experiment for measuring methyl-methyl NOEs in C-13-labeled proteins with high resolution J. Am. Chem. Soc. 120 1998 7617 7625