2,3′,4,5′-Tetramethoxystilbene prevents deoxycorticosterone- salt-induced hypertension: Contribution of cytochrome P-450 1B1

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 299, Issue 6, 2010, Pages

  Sahan Firat, Seyhan ^a   Jennings, Brett L ^a   Yaghini, Fariborz A ^a   Song, Chi Young ^a   Estes, Anne M ^a   Fang, Xiao R ^a   Farjana, Nasreen ^a   Khan, Amir I ^a   Malik, Kafait U ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

Cytochrome P 450 1B1 activity; Endothelial dysfunction; Reactive oxygen species; Renal function; Vascular reactivity

Indexed keywords

2,3',4,5' TETRAMETHOXYSTILBENE; CREATININE; CYTOCHROME P450 INHIBITOR; DEOXYCORTICOSTERONE ACETATE; DRINKING WATER; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; POTASSIUM CHLORIDE; POTASSIUM ION; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SODIUM CHLORIDE; SODIUM ION; SUPEROXIDE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; 12 HYDROXYICOSATETRAENOIC ACID; 2,4,3',5' TETRAMETHOXYSTILBENE; 2,4,3',5'-TETRAMETHOXYSTILBENE; 20 HYDROXY 5,8,11,14 EICOSATETRAENOIC ACID; 20-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID; ANTIHYPERTENSIVE AGENT; CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; DEOXYCORTICOSTERONE; ENZYME INHIBITOR; HYDROXYICOSATETRAENOIC ACID; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDOREDUCTASE; STILBENE DERIVATIVE; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; CREATININE URINE LEVEL; ENDOTHELIAL DYSFUNCTION; HEART; HEART HYPERTROPHY; HYPERTENSION; KIDNEY; KIDNEY HYPERTROPHY; MALE; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RAT; SODIUM URINE LEVEL; SYSTOLIC BLOOD PRESSURE; URINE OSMOLALITY; ANIMAL; BLOOD; BLOOD PRESSURE; CARDIOMEGALY; DISEASE MODEL; DIURESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART MUSCLE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PROTEINURIA; SALT INTAKE; SPRAGUE DAWLEY RAT; TIME; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; VASODILATATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA; ARYL HYDROCARBON HYDROXYLASES; BLOOD PRESSURE; CARDIOMEGALY; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; DIURESIS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HYDROXYEICOSATETRAENOIC ACIDS; HYPERTENSION; KIDNEY; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; NADH, NADPH OXIDOREDUCTASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEINURIA; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE, DIETARY; STILBENES; SUPEROXIDES; TIME FACTORS; VASOCONSTRICTION; VASODILATION;

EID: 78649731418     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00655.2010     Document Type: Article

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