Secretory effects of a luminal bitter tastant and expressions of bitter taste receptors, T2Rs, in the human and rat large intestine

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 296, Issue 5, 2009, Pages

  Kaji, Izumi ^a   Karaki, Shin Ichiro ^a   Fukami, Yasuyuki ^b   Terasaki, Masaki ^b   Kuwahara, Atsukazu ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b SHIZUOKA SAISEIKAI GENERAL HOSPITAL   (Japan)

Author keywords

6 n propyl 2 thiouracil; Intestinal chemosensing; Prostaglandin E2; Taste receptor type 2; Transepithelial ion transport

Indexed keywords

BICARBONATE; CHLORIDE ION; RECEPTOR; TASTE RECEPTOR TYPE 2; UNCLASSIFIED DRUG; CHLORIDE; G PROTEIN COUPLED RECEPTOR; MESSENGER RNA; PIROXICAM; PROPYLTHIOURACIL; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; SODIUM CHANNEL BLOCKING AGENT; TASTE RECEPTORS, TYPE 2; TETRODOTOXIN;

AGED; ANIMAL TISSUE; ARTICLE; BITTER TASTE; CHLORIDE TRANSPORT; COLON; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; INTESTINE MUCOSA; ION TRANSPORT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR INTRINSIC ACTIVITY; SUBMUCOSA; TASTE BUD; ANIMAL; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG EFFECT; ELECTROSTIMULATION; GENETICS; INTESTINE SECRETION; LARGE INTESTINE; METABOLISM; TIME; WISTAR RAT;

AGED; ANIMALS; BICARBONATES; CHLORIDES; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; FEMALE; HUMANS; INTESTINAL MUCOSA; INTESTINAL SECRETIONS; INTESTINE, LARGE; MALE; MEMBRANE POTENTIALS; PIROXICAM; PROPYLTHIOURACIL; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; TIME FACTORS;

EID: 66149112487     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90514.2008     Document Type: Article

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