Modern biotechnological polymer synthesis: A review

Food Technology and Biotechnology

Volumn 48, Issue 3, 2010, Pages 255-269

  Koller, Martin ^a   Salerno, Anna ^a,b   Dias, Miguel ^a   Reiterer, Angelika ^a   Braunegg, Gerhart ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b UNIVERSITY OF NAPLES PARTHENOPE   (Italy)

Author keywords

Biopolymers; Downstream processing; Fermentation strategy; Polyhydroxyalkanoates; Process design; Raw materials; White biotechnology

Indexed keywords

DOWNSTREAM-PROCESSING; FED-BATCH FERMENTATION; INDUSTRIAL IMPLEMENTATION; INFLUENCE ON THE ENVIRONMENTS; KINETIC CHARACTERISTICS; POLYHYDROXYALKANOATES; PROCESS PARAMETERS; WHITE BIOTECHNOLOGY;

BIOCHEMISTRY; BIOPOLYMERS; BIOTECHNOLOGY; FERMENTATION; INDUSTRIAL APPLICATIONS; METABOLISM; PROCESS DESIGN; RAW MATERIALS;

BIOMOLECULES;

EID: 78649721352     PISSN: 13309862     EISSN: 13342606     Source Type: Journal    
DOI: None     Document Type: Article

References (82)

1. G. Braunegg, R. Bona, M. Koller, Sustainable polymer production, Polym. Plast. Technol. Eng. 43 (2004) 1779-1793.
2. V. Gorenflo, A. Steinbüchel, S. Marose, M. Rieseberg, T. Scheper, Quantification of bacterial polyhydroxyalkanoic acids by Nile red staining, Appl. Microbiol. Biotechnol. 51 (1999) 765-772.
3. D.K.Y. Solaiman, R.D. Ashby, A.T. Hotchkiss Jr, T.A. Foglia, Biosynthesis of medium-chain-length poly(hydroxyalkanoates) from soy molasses, Biotechnol. Lett. 28 (2006) 157-162.
4. J. Cornibert, R.H. Marchessault, Conformational isomorphism. A general 21 helical conformation for poly(β-alkanoates), Macromolecules, 8 (1975) 296-305.
5. 13C-NMR spectroscopy, FEBS Lett. 231 (1988) 16-18.
6. Y.B. Kim, R.W. Lenz, Polyesters from microorganisms, Adv. Biochem. Eng. Biotechnol. 71 (2001) 51-79.
7. L.L. Wallen, W.K. Rhowedder, Poly-beta-hydroxyalkanoate from activated sludge, Environ. Sci. Technol. 8 (1974) 576-579.
8. R.H. Findlay, D.C. White, Polymeric beta-hydroxyalkanoates from environmental samples and Bacillus megaterium, Appl. Environ. Microbiol. 45 (1983) 71-78.
9. A. Steinbüchel, H.E. Valentin, Diversity of bacterial polyhydroxyalkanoic acids, FEMS Microbiol. Lett. 128 (1995) 219-228.
10. S.Y. Lee, Y. Lee, Metabolic engineering of Escherichia coli for production of enantiomerically pure (R)-(-)-hydroxycarboxylic acids, Appl. Environ. Microbiol. 69 (2003) 3421-3426.
11. E. Shimamura, K. Kasuya, G. Kobayashi, T. Shiotani, Y. Shima, Y. Doi, Physical properties and biodegradability of microbial poly(3-hydroxybutyrate-co-3-hydroxyhexanoate), Macromolecules, 27 (1994) 878-880.
12. G.J. McCool, M.C. Cannon, PhaC and PhaR are required for polyhydroxyalkanoic acid synthase activity in Bacillus megaterium, J. Bacteriol. 183 (2001) 4235-4243.
13. H. Abe, I. Matsubara, Y. Doi, Y. Hori, A. Yamaguchi, Physical properties and enzymatic degradability of poly-(3-hydroxybutyrate) stereoisomers with different stereoregularities, Macromolecules, 27 (1994) 6018-6025.
14. D.Y. Kim, K. Elbanna, N. Thakor, T. Lütke-Eversloh, A. Steinbüchel, Poly(3-mercaptopropionate): A non-biodegradable biopolymer?, Biomacromolecules, 6 (2005) 897-901.
15. J. Agus, P. Kahar, H. Abe, Y. Doi, T. Tsuge, Molecular weight characterization of poly[(R)-3-hydroxybutyrate] synthesized by genetically engineered strains of Escherichia coli, Polym. Degrad. Stabil. 91 (2006) 1138-1146.
16. A. Steinbüchel, S. Hein, Biochemical and molecular basis of microbial synthesis of polyhydroxyalkanoates in microorganisms, Adv. Biochem. Eng. Biotechnol. 71 (2001) 81-123.
17. A. Steinbüchel, T. Lütke-Eversloh, Metabolic engineering and pathway construction for biotechnological production of relevant polyhydroxyalkanoates in microorganisms, Biochem. Eng. J. 16 (2003) 81-96.
18. M. Zinn, B. Witholt, T. Egli, Occurrence, synthesis and medical application of bacterial polyhydroxyalkanoate, Adv. Drug Deliv. Rev. 53 (2001) 5-21.
19. S. Khanna, A.K. Srivastava, Recent advances in microbial polyhydroxyalkanoates, Process Biochem. 40 (2005) 607-619.
20. S.F. Williams, D.P. Martin: Applications of PHAs in Medicine and Pharmacy. In: Biopolymers, Vol. 4: Polyesters III - Applications and Commercial Products, Y. Doi, A. Steinbüchel (Eds.), Wiley-VCH, Weinheim, Germany (2002) pp. 91-127.
21. Y. Doi: Microbial Polyesters, VCH Publishers Inc, Yokohama, Japan (1990) pp. 33-61.
22. Y. Poirier, C. Nawrath, C. Sommerville, Production of polyhydroxyalkanoates, a family of biodegradable plastics and elastomers, in bacteria and plants, Biotechnology, 13 (1995) 142-150.
23. S.Y. Lee, Bacterial polyhydroxyalkanoates, Biotechnol. Bioeng. 49 (1996) 1-14.
24. T.V. Ojumu, J. Yu, B.O. Solomon, Production of polyhydroxyalkanoates, a bacterial biodegradable polymer, Afr. J. Biotechnol. 3 (2004) 18-24.
25. H. Son, S. Lee, Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) from structurally unrelated single carbon sources by newly isolated Pseudomonas sp. EL-2, Biotechnol. Lett. 18 (1996) 1217-1222.
26. F. Rodriguez-Valera, J.A.G. Lillo, Halobacteria as producers of polyhydroxyalkanoates, FEMS Microbiol. Rev. 103 (1992) 181-186.
27. H.M. Alvarez, R. Kalscheuer, A. Steinbüchel, Accumulation of storage lipids in species of Rhodococcus and Nocardia and effect of inhibitors and polyethylene glycol, Fett-Lipid, 99 (1997) 239-246.
28. H.E. Valentin, D. Dennis, Metabolic pathway for poly(3-hydroxybutyrate-co-3-hydroxyvalerate) formation in Nocardia corallina: Inactivation of mutB by chromosomal integration of a kanamycin resistance gene, Appl. Environ. Microbiol. 62 (1996) 372-379.
29. A. Akar, E.U. Akkaya, S.K. Yesiladali, G. Celikyilmaz, E.U. Cokgor, C. Tamerler, D. Orhon, Z.P. Cakar, Accumulation of polyhydroxyalkanoates by Microlunatus phosphovorus under various growth conditions, J. Ind. Microbiol. Biotechnol. 33 (2006) 215-220.
30. M. Liebergesell, E. Hustede, A. Timm, A. Steinbüchel, R.C. Fuller, R.W. Lenz, H.G. Schlegel, Formation of poly(3-hydroxyalkanoates) by phototrophic and chemolithotrophic bacteria, Arch. Microbiol. 155 (1991) 415-421.
31. M.F.A. Rodrigues, L.F. da Silva, J.G.C. Gomez, H.E. Valentin, A. Steinbüchel, Biosynthesis of poly(3-hydroxybutyric acid co-3-hydroxy-4-pentenoic acid) from unrelated substrates by Burkholderia sp., Appl. Microbiol. Biotechnol. 43 (1995) 880-886.
32. mcl) produced by Pseudomonas putida IPT 046 from renewable sources, Eur. Polym. J. 39 (2003) 1385-1394.
33. G. Lefebvre, M. Rocher, G. Braunegg, Effects of low dissolved-oxygen concentrations on poly-(3-hydroxybutyrate-co-3-hydroxyvalerate) production by Alcaligenes eutrophus, Appl. Environ. Microbiol. 63 (1997) 827-833.
34. J.S. Kim, B.H. Lee, B.S. Kim, Production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) by Ralstonia eutropha, Biochem. Eng. J. 23 (2005) 169-174.
35. Y.H. Lee, M.S. Kang, Y.M. Jung, Regulating the molar fraction of 4-hydroxybutyrate in poly(3-hydroxybutyrate-4-hydroxybutyrate) biosynthesis by Ralstonia eutropha, using propionate as a stimulator, J. Biosci. Bioeng. 89 (2000) 380-383.
36. N. Narayanan, P.K. Roychoudhury, A. Srivastava, L(+) lactic acid fermentation and its product polymerization, Electron. J. Biotechnol. 7 (2004) 167-178.
37. H.O. Kim, Y.J. Wee, J.N. Kim, J.S. Yun, H.W. Ryu, Production of lactic acid from cheese whey by batch and repeated batch cultures of Lactobacillus sp. RKY2, Appl. Biochem. Biotechnol. 131 (2006) 694-704.
38. R.E. Drumright, P.R. Gruber, D.E. Henton, Polylactic acid technology, Adv. Mater. 12 (2000) 1841-1846.
39. Y.J. Wee, J.N. Kim, H.W. Ryu, Biotechnological production of lactic acid and its recent applications, Food Technol. Biotechnol. 44 (2006) 163-172.
40. S. Taguchi, M. Yamada, K. Matsumoto, K. Tajima, Y. Satoh, M. Munekata, K. Ohno, K. Kohda, T. Shimamura, H. Kambe, S. Obata, A microbial factory for lactate-based polyesters using a lactate-polymerizing enzyme, PNAS, 105 (2008) 17323-17327.
41. K. Sudesh, T. Iwata, Sustainability of biobased and biodegradable plastics, Acta Hydrochim. Hydrobiol. 36 (2008) 433-442.
42. G. Braunegg, G. Lefebvre, K.F. Genser, Polyhydroxyalkanoates, biopolyesters from renewable resources: Physiological and engineering aspects, J. Biotechnol. 65 (1998) 127-161.
43. D.K.Y. Solaiman, R.D. Ashby, T.A. Foglia, W.N. Marmer, Conversion of agricultural feedstock and coproducts into poly(hydroxyalkanoates), Appl. Microbiol. Biotechnol. 71 (2006) 783-789.
44. A.A. Khardenavis, M.S. Kumar, S.N. Mudliar, T. Chakrabarti, Biotechnological conversion of agro-industrial wastewaters into biodegradable plastic, poly β-hydroxybutyrate, Bioresour. Technol. 98 (2007) 3579-3584.
45. M. Koller, R. Bona, G. Braunegg, C. Hermann, P. Horvat, M. Kroutil, J. Martinz, J. Neto, L. Pereira, P. Varila, Production of polyhydroxyalkanoates from agricultural waste and surplus materials, Biomacromolecules, 6 (2005) 561-565.
46. R.D. Ashby, D.K.Y. Solaiman, T.A. Foglia, Bacterial poly-(hydroxyalkanoate) polymer production from biodiesel co-product stream, J. Polym. Environ. 12 (2004) 105-112.
47. M. Koller, P. Hesse, R. Bona, C. Kutschera, A. Atli, G. Braunegg, Potential of various archae- and eubacterial strains as industrial polyhydroxyalkanoate producers from whey, Macromol. Biosci. 7 (2007) 218-226.
48. M. Koller, R. Bona, C. Hermann, P. Horvat, J. Martinz, J. Neto, P. Varila, G. Braunegg, Biotechnological production of poly(3-hydroxybutyrate) with Wautersia eutropha by application of green grass juice and silage juice as additional complex substrates, Biocatal. Biotransform. 23 (2005) 329-337.
49. H. Zhang, V. Obias, K. Gonyer, D. Dennis, Production of polyhydroxyalkanoates in sucrose-utilizing recombinant Escherichia coli and Klebsiella strains, Appl. Environ. Microbiol. 60 (1994) 1198-1205.
50. J.I. Choi, S.Y. Lee, Efficient and economical recovery of poly(3-hydroxybutyrate) from recombinant Escherichia coli by simple digestion with chemicals, Biotechnol. Bioeng. 62 (1999) 546-553.
51. T. Fukui, Y. Doi, Efficient production of polyhydroxyalkanoates from plant oils by Alcaligenes eutrophus and its recombinant strain, Appl. Microbiol. Biotechnol. 49 (1998) 333-336.
52. P.Y. Bourque, Y. Pomerleau, D. Groleau, High-cell-density production of poly-β-hydroxybutyrate (PHB) from methanol by Methylobacterium extorquens: Production of high-molecular-mass PHB, Appl. Microbiol. Biotechnol. 44 (1995) 367-376.
53. G. Braunegg, M. Koller, P. Varila, C. Kutschera, R. Bona, C. Hermann, P. Horvat, J. Neto, L. Pereira: Production of Plastics from Waste Derived from Agrofood Industry. In: Renewable Resources and Renewable Energy: A Global Challenge, M. Graziani, P. Fornasiero (Eds.), CRC Press, Taylor&Francis Group, Boca Raton, FL, USA (2007) pp. 119-135.
54. R. Kumar, S. Singh, O.V. Singh, Bioconversion of lignocellulosic biomass: Biochemical and molecular perspectives, J. Ind. Microbiol. Biotechnol. 35 (2008) 377-391.
55. D. Peters, Carbohydrates for fermentation, Biotechnol. J. 1 (2006) 806-814.
56. R.V. Nonato, P.E. Mantelatto, C.E.V. Rossell, Integrated production of biodegradable plastic, sugar and ethanol, Appl. Microbiol. Biotechnol. 57 (2001) 1-5.
57. G. Braunegg, G. Lefebvre, G. Renner, A. Zeiser, G. Haage, K. Loidl-Lanthaler, Kinetics as a tool for polyhydroxyalkanoate production optimization, Can. J. Microbiol. 41 (1995) 239-248.
58. G. Du, J. Chen, J. Yu, S. Lun, Continuous production of poly-3-hydroxybutyrate by Ralstonia eutropha in a two-stage culture system, J. Biotechnol. 88 (2001) 59-65.
59. N. Koyama, Y. Doi, Continuous production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Alcaligenes eutrophus, Biotechnol. Lett. 17 (1995) 281-284.
60. S. Aiba, A.E. Humphrey, N.F. Millis: Biochemical Engineering, Academic Press, Inc., New York, NY, USA (1973).
61. M. Zlokarnik, Suitability of stirrers for homogenization and mixing of liquid mixtures, Chem. Ing. Technol. 39 (1967) 539-548 (in German).
62. R. Hartmann, R. Hany, E. Pletscher, A. Ritter, B. Witholt, M. Zinn, Tailor-made olefinic medium-chain-length poly-[(R)-3-hydroxyalkanoates] by Pseudomonas putida GPo1: Batch versus chemostat production, Biotechnol. Bioeng. 93 (2001) 737-746.
63. R. Hartmann, R. Hany, T. Geiger, T. Egli, B. Witholt, M. Zinn, Tailored biosynthesis of olefinic medium-chain-length poly[(R)-3-hydroxyalkanoates] in Pseudomonas putida GPo1 with improved thermal properties, Macromolecules, 37 (2004) 6780-6785.
64. B.A. Ramsay, K. Lomaliza, C. Chavarie, B. Dubé, P. Bataille, J.A. Ramsay, Production of poly-(β-hydroxybutyric-co -β-hydroxyvaleric) acids, Appl. Environ. Microbiol. 56 (1990) 2093-2098.
65. S.T. Yu, C.C. Lin, J.R. Too, PHBV production by Ralstonia eutropha in a continuous stirred tank reactor, Process Biochem. 40 (2005) 2729-2734.
66. M. Zinn, H.U. Weilenmann, R. Hany, M. Schmid, T. Egli, Tailored synthesis of poly([R]-3-hydroxybutyrate-co-3-hydroxyvalerate) (PHB/HV) in Ralstonia eutropha DSM 428, Acta Biotechnol. 23 (2003) 309-316.
67. G. Mothes, J.U. Ackermann, Synthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) with a target mole fraction of 4-hydroxybutyric acid units by two-stage continuous cultivation of Delftia acidovorans P4a, Eng. Life Sci. 5 (2005) 58-62.
68. K. Jung, W. Hazenberg, M. Prieto, B. Witholt, Two-stage continuous process development for the production of medium-chain-length poly(3-hydroxyalkanoates), Biotechnol. Bioeng. 72 (2001) 19-24.
69. G.Q. Chen, G. Zhang, S.J. Park, S.Y. Lee, Industrial scale production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate), Appl. Microbiol. Biotechnol. 57 (2001) 50-55.
70. M. Terada, R.H. Marchessault, Determination of solubility parameters for poly(3-hydroxyalkanoates), Int. J. Biol. Macromol. 25 (1999) 207-215.
71. J. Choi, S.Y. Lee, Factors affecting the economics of polyhydroxyalkanoate production by bacterial fermentation, Appl. Microbiol. Biotechnol. 51 (1999) 13-21.
72. G. Braunegg, R. Bona, F. Schellauf, E. Wallner, Polyhydroxyalkanoates (PHAs): Sustainable biopolyester production, Polimery, 47 (2002) 13-18.
73. K. Metzner, M. Sela, J. Schaffer, Agents for extracting polyhydroxyalkane acids. WO patent 9708931 (1997).
74. P.A. Holmes, G.B. Lim, Separation process. US patent 4910145 (1990).
75. K. Yasotha, M.K. Aroua, K.B. Ramachandran, I.K.P. Tan, Recovery of medium-chain-length polyhydroxyalkanoates (PHAs) through enzymatic digestion treatments and ultrafiltration, Biochem. Eng. J. 30 (2006) 260-268.
76. E. Berger, B.A. Ramsay, J.A. Ramsay, C. Chavarie, G. Braunegg, PHB recovery by hypochlorite digestion of non-PHB biomass, Biotechnol. Technique, 3 (1989) 227-232.
77. B. Ramsay, J. Ramsay, E. Berger, C. Chavarie, G. Braunegg, Separation of poly-beta-hydroxyalkanoic acid from microbial biomass. US patent 5110980 (1992).
78. M. Kim, K.S. Cho, H.W. Ryu, E.G. Lee, Y.K. Chang, Recovery of poly(3-hydroxybutyrate) from high cell density culture of Ralstonia eutropha by direct addition of sodium dodecyl sulphate, Biotechnol. Lett. 25 (2003) 55-59.
79. R.M. Lafferty, E. Heinzle, Cyclic carbonic acid esters as solvents for poly-(β-hydroxybutyric acid. US patent 4101533 (1978).
80. M.S. Ghatnekar, J.S. Pa, M. Ganesh, Production and recovery of poly-3-hydroxybutyrate from Methylobacterium sp. V49, J. Chem. Technol. Biotechnol. 77 (2002) 444-448.
81. I. Chodak: Polyhydroxyalkanoates: Properties and Modification for High Volume Applications. In: Degradable Polymers: Principles and Applications, G. Scott (Ed.), Kluwer Academic Publishers, Dordrecht, the Netherlands (2002) pp. 295-319.
82. E.A. Muñoz-Escalona, F. Rodríguez-Valera, A. Marcilla Gomis, Procedure for the extraction of polyhydroxyalkanoates from halophilic bacteria which contain them. European patent 0622462 (1994).