Effects of low dissolved-oxygen concentrations on poly-(3- hydroxybutyrate-co-3-hydroxyvalerate) production by Alcaligenes eutrophus

Applied and Environmental Microbiology

Volumn 63, Issue 3, 1997, Pages 827-833

  Lefebvre, Gilles ^a,b   Rocher, Magali ^a,c   Braunegg, Gerhart ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c INSA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COPOLYMER; GLUCOSE; POLY(3 HYDROXYBUTYRIC ACID); PROPIONIC ACID; SODIUM;

ALCALIGENES; ARTICLE; BIODEGRADATION; CELL COMPOSITION; FERMENTATION; OXYGENATION; SPECIES DIFFERENCE;

ALCALIGENES; BACTERIA (MICROORGANISMS); WAUTERSIA EUTROPHA;

EID: 0031027781     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.63.3.827-833.1997     Document Type: Article

References (30)

1. Anderson, A. J., and E. A. Dawes. 1990. Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates. Microbiol. Rev. 54:450-472.
2. Bertrand, J.-L., B. A. Ramsay, J. A. Ramsay, and C. Chavarie. 1990. Biosynthesis of poly-β-hydroxyalkanoates from pentoses by Pseudomonas pseudoflava. Appl. Environ. Microbiol. 56:3133-3138.
3. Braunegg, G., G. Lefebvre, G. Renner, A. Zeiser, G. Haage, and K. Loidl-Lanthaler. 1995. Kinetics as a tool for polyhydroxyalkanoate production optimization. Can. J. Microbiol. 41(Suppl. 1):239-248.
4. Braunegg, G., B. Sonnleitner, and R. M. Lafferty. 1978. A rapid method for the determination of poly-β-hydroxybutyric acid in microbial biomass. Eur. J. Appl. Microbiol. Biotechnol. 6:29-37.
5. Byrom, D. 1992. Production of poly-β-hydroxybutyrate:poly-β-hydroxyvalerate copolymers. FEMS Microbiol. Rev. 103:247-250.
6. Byrom, D. 1987. Polymer synthesis by microorganisms: technology and economics. Trends Biotechnol. 5:246-250.
7. Carter, I. S., and E. A. Dawes. 1979. Effect of oxygen concentration and growth rate on glucose metabolism, poly-β-hydroxybutyrate biosynthesis and respiration of Azotobacter beijerinckii. J. Gen. Microbiol. 110:393-400.
8. 13C-labeled acetate and propionate. Macromolecules 20:2988-2991.
9. Haywood, G. W., A. J. Anderson, L. Chu, and E. A. Dawes. 1988. Characterization of two 3-ketothiolases possessing differing substrate specificities in the polyhydroxyalkanoate synthesizing organism Alcaligenes eutrophus. FEMS Microbiol. Lett. 52:91-96.
10. Holmes, P. A. 1988. Biologically produced (R)-3-hydroxyalkanoate polymers and copolymers. In D. C. Basset (ed.), Development in crystalline polymers - 2. Elsevier, London, England.
11. Jackson, F. A., and E. A. Dawes. 1976. Regulation of the tricarboxylic acid cycle and poly-β-hydroxybutyrate metabolism in Azotobacter beijerinckii grown under nitrogen or oxygen limitation. J. Gen. Microbiol. 97:303-312.
12. Kim, B. S., S. Y. Lee, and H. N. Chang. 1992. Production of poly-β-hydroxybutyrate by fed-batch culture of recombinant Escherichia coli. Biotechnol. Lett. 14:811-816.
13. Luzier, W. D. 1992. Materials derived from biomass/biodegradable materials. Proc. Natl. Acad. Sci. USA 89:839-842.
14. Nawrath, C., Y. Poirier, and C. Somerville. 1994. Targeting of the polyhydroxybutyrate biosynthetic pathway to the plastids of Arabidopsis thaliana results in high levels of polymer accumulation. Proc. Natl. Acad. Sci. USA 91:12760-12764.
15. Naylor, L. (Zeneca Bio Products, Billingham, England). 1995. Personal communication.
16. Page, W. J. 1992. Suitability of commercial beet molasses fractions as substrates for polyhydroxyalkanoate production by Azotobacter vinelandii UWD. Biotechnol. Lett. 14:385-390.
17. Ramsay, B. A., K. Lomaliza, C. Chavarie, B. Dubé, P. Bataille, and J. A. Ramsay. 1990. Production of poly-(β-hydroxybutyric-co-β-hydroxyvaleric) acids. Appl. Environ. Microbiol. 56:2093-2098.
18. Renner, G., G. Haage, and G. Braunegg. 1996. Production of short-side-chain polyhydroxyalkanoates by various bacteria from the rRNA superfamily III. Appl. Microbiol. Biotechnol. 46:268-272.
19. Repaske, R., and C. Repaske. 1976. Quantitative requirements for exponential growth of Alcaligenes eutrophus. Appl. Environ. Microbiol. 32:585-591.
20. Rotman, D. 1996. Monsanto takes a chance on Zeneca's Biopol technology. Chem. Week 158(17):21.
21. Schubert, P., A. Steinbüchel, and H. G. Schlegel. 1988. Cloning of the Alcaligenes eutrophus genes for synthesis of poly-β-hydroxybutyric acid (PHB) and synthesis of PHB in Escherichia coli. J. Bacteriol. 170:5837-5847.
22. Senior, P. J., G. A. Beech, G. A. F. Ritchie, and E. A. Dawes. 1972. The role of oxygen limitation in the formation of poly-β-hydroxybutyrate during batch and continuous culture of Azotobacter beijerinckii. Biochem. J. 128:1193-1201.
23. Sheppard, J. D., P. Marchessault, T. Whalen, and S. F. Barrington. 1994. Scale-up of a cyclone bioreactor. J. Chem. Tech. Biotechnol. 54:83-89.
24. Slater, S. C., W. H. Voige, and D. E. Dennis. 1988. Cloning and expression in Escherichia coli of the Alcaligenes eutrophus H16 poly-β-hydroxybutyrate biosynthetic pathway. J. Bacteriol. 170:4431-4436.
25. Sonnleitner, B. 1979. Formalkinetik der mikrobiellen Produktion von Poly-β-Hydroxybuttersäure (PHB). Ph.D. thesis. Technische Universität Graz, Graz, Austria.
26. Sonnleitner, B., E. Heinzle, G. Braunegg, and R. M. Lafferty. 1979. Formal kinetics of poly-β-hydroxybutyric acid (PHB) production in Alcaligenes eutrophus H 16 and Mycoplana rubra R 14 with respect to the dissolved-oxygen tension in ammonium-limited batch cultures. Eur J Appl Microbiol. Biotechnol. 7:1-10.
27. Steinbüchel, A., and H. G. Schlegel. 1989. Excretion of pyruvate by mutants of Alcaligenes eutrophus, which are impaired in the accumulation of poly(β-hydroxybutyric acid) (PHB), under conditions permitting synthesis of PHB. Appl. Microbiol. Biotechnol. 31:168-175.
28. Tanaka, K., K. Katamune, and A. Ishizaki. 1993. Fermentative production of poly-β-hydroxybutyric acid from xylose by a two-stage culture method employing Lactococcus lactis IO-1 and Alcaligenes eutrophus. Biotechnol. Lett. 15:1217-1222.
29. Vollbrecht, D., H. G. Schlegel, G. Stoschek, and A. Janczikowski. 1979. Excretion of metabolites by hydrogen bacteria. IV. Respiration rate-dependent formation of primary metabolites and of poly-3-hydroxybutanoate. Eur. J. Appl. Microbiol. Biotechnol. 7:267-276.
30. Williams, M. D., J. A. Rahn, and D. H. Sherman. 1996. Production of a polyhydroxyalkanoate biopolymer in insect cells with a modified eucaryotic fatty acid synthase. Appl. Environ. Microbiol. 62:2540-2546.