Caenorhabditis elegans UBX cofactors for CDC-48/p97 control spermatogenesis

Genes to Cells

Volumn 15, Issue 12, 2010, Pages 1201-1215

  Sasagawa, Yohei ^a,b   Yamanaka, Kunitoshi ^a   Saito Sasagawa, Yuko ^a   Ogura, Teru ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b RIKEN Center for Biosystems Dynamics Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; PROTEIN P97; UBIQUITIN; UBXN 1 PROTEIN; UBXN 2 PROTEIN; UBXN 3 PROTEIN; UBXN 4 PROTEIN; UBXN 5 PROTEIN; UBXN 6 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE PROGRESSION; CELL NUCLEUS MEMBRANE; EMBRYO DEVELOPMENT; ENDOPLASMIC RETICULUM; GAMETOGENESIS; GENE EXPRESSION; GENE SILENCING; GERM LINE; HERMAPHRODITISM; NONHUMAN; OOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SEX DETERMINATION; SPERM; SPERMATOCYTE; SPERMATOGENESIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL CYCLE PROTEINS; PROTEIN STRUCTURE, TERTIARY; SPERMATOGENESIS; UBIQUITIN;

CAENORHABDITIS ELEGANS;

EID: 78649715872     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2010.01454.x     Document Type: Article

References (59)

1. Alexandru, G., Graumann, J., Smith, G.T., Kolawa, N.J., Fang, R. & Deshaies, R.J. (2008) UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1α turnover. Cell 134, 804-816.
2. Bays, N.W., Wilhovsky, S.K., Goradia, A., Hodgkiss-Harlow, K. & Hampton, R.Y. (2001) HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol. Biol. Cell 12, 4114-4128.
3. UFD1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J. 21, 615-621.
4. Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
5. Bruderer, R.M., Brasseur, C. & Meyer, H.H. (2004) The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism. J. Biol. Chem. 279, 49609-49616.
6. Buchberger, A., Howard, M.J., Proctor, M. & Bycroft, M. (2001) The UBX domain: a widespread ubiquitin-like module. J. Mol. Biol. 307, 17-24.
7. Dai, R.M. & Li, C.C. (2001) Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation. Nat. Cell Biol. 3, 740-744.
8. DeLaBarre, B. & Brunger, A.T. (2003) Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains. Nat. Struct. Biol. 10, 856-863.
9. Dreveny, I., Kondo, H., Uchiyama, K., Shaw, A., Zhang, X. & Freemont, P.S. (2004) Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. EMBO J. 23, 1030-1039.
10. Ellis, R. & Schedl, T. (2006) Sex determination in the germ line. Wormbook The C. elegans Research Community, WormBook. doi/,
11. Hetzer, M., Meyer, H.H., Walther, T.C., Bilbao-Cortes, D., Warren, G. & Mattaj, I.W. (2001) Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nat. Cell Biol. 3, 1086-1091.
12. Higashiyama, H., Hirose, F., Yamaguchi, M., Inoue, Y.H., Fujikake, N., Matsukage, A. & Kakizuka, A. (2002) Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration. Cell Death Differ. 9, 264-273.
13. Hodgkin, J. (1987) A genetic analysis of the sex-determination gene, tra-1, in the nematode Caenorhabditis elegans. Genes Dev. 1, 731-745.
14. Hsu, J.Y., Sun, Z.W., Li, X., Reuben, M., Tatchell, K., Bishop, D.K., Grushcow, J.M., Brame, C.J., Caldwell, J.A., Hunt, D.F., Lin, R., Smith, M.M. & Allis, C.D. (2000) Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102, 279-291.
15. Jarosch, E., Taxis, C., Volkwein, C., Bordallo, J., Finley, D., Wolf, D.H. & Sommer, T. (2002) Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat. Cell Biol. 4, 134-139.
16. Jentsch, S. & Rumpf, S. (2007) Cdc48p (p97): a 'molecular gearbox' in the ubiquitin pathway? Trends Biochem. Sci. 32, 6-11.
17. Kamath, R.S., Martinez-Campos, M., Zipperlen, P., Fraser, A.G. & Ahringer, J. (2001) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol. 2, RESEARCH0002.1-0002.10.
18. Kern, M., Fernandez-Salz, V., Schafer, Z. & Buchberger, A. (2009) UBXD1 binds p97 through two independent binding sites. Biochem. Biophys. Res. Commun. 380, 303-307.
19. Kimble, J. & Crittenden, S.L. (2007) Controls of germline stem cells, entry into meiosis, and the sperm/oocytes decision in C. elegans. Annu. Rev. Cell Dev. Biol. 23, 405-433.
20. Kobayashi, T., Manno, A. & Kakizuka, A. (2007) Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates. Genes Cells 12, 889-901.
21. Kondo, H., Rabouille, C., Newman, R., Levine, T.P., Pappin, D., Freemont, P. & Warren, G. (1997) p47 is a cofactor for p97-mediated membrane fusion. Nature 338, 75-78.
22. Latterich, M., Frohlich, K.U. & Scheckman, R. (1995) Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes. Cell 82, 885-893.
23. Madsen, L., Andersen, K.M., Prag, S., Moos, T., Semple, C.A., Seeger, M. & Hartmann-Petersen, R. (2008) Ubxd1 is a novel co-factor of the human p97 ATPase. Int. J. Biochem. Cell Biol. 40, 2927-2942.
24. Meyer, H.H., Shorter, J.G., Seemann, J., Pappin, D. & Warren, G. (2000) A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J. 19, 2181-2192.
25. Moir, D., Stewart, S.E., Osmond, B.C. & Botstein, D. (1982) Cold-sensitive cell-division-cycle mutants of yeast: isolation, properties, and pseudoreversion studies. Genetics 100, 547-563.
26. UFD-1/NPL-4 complex for efficient DNA replication. Proc. Natl Acad. Sci. USA 105, 12879-12884.
27. Mouysset, J., Kahler, C. & Hoppe, T. (2006) A conserved role of Caenorhabditis elegans CDC-48 in ER-associated protein degradation. J. Struct. Biol. 156, 41-49.
28. Neuber, O., Jarosch, E., Volkwein, C., Walter, J. & Sommer, T. (2005) Ubx2 links the Cdc48 complex to ER-associated protein degradation. Nat. Cell Biol. 7, 993-998.
29. Nishikori, S., Yamanaka, K., Sakurai, T., Esaki, M. & Ogura, T. (2008) p97 homologs from Caenorhabditis elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat. Genes Cells 13, 827-838.
30. Patel, S. & Latterich, M. (1998) The AAA team: related ATPases with diverse functions. Trends Cell Biol. 8, 65-71.
31. Praitis, V., Casey, E., Collar, D. & Austin, J. (2001) Creation of low-copy integrated transgenic line in Caenorhabditis elegans. Genetics 157, 1217-1226.
32. Rabinovich, E., Keren, A., Frohlich, K.U., Diamant, N. & Bar Nun, S. (2002) AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation. Mol. Cell. Biol. 22, 626-634.
33. Rabouille, C., Levine, T.P., Peters, J.M. & Warren, G. (1995) An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. Cell 82, 905-914.
34. Ramadan, K., Bruderer, R., Spiga, F.M., Popp, O., Baur, T., Gotta, M. & Meyer, H.H. (2007) Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin. Nature 450, 1258-1262.
35. UFD1/NPL4, a ubiquitin-selective chaperone. Cell 107, 667-677.
36. Rouiller, I., DeLaBarre, B., May, A.P., Weis, W.I., Brunger, A.T., Milligan, R.A. & Wilson-Kubalek, E.M. (2002) Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle. Nat. Struct. Biol. 9, 950-957.
37. Rumpf, S. & Jentsch, S. (2006) Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone. Mol. Cell 21, 261-269.
38. Sasagawa, Y., Kikuchi, K., Dazai, K. & Higashitani, A. (2005) Caenorhabditis elegans Elongin BC complex is essential for cell proliferation and chromosome condensation and segregation during mitosis and meiotic division II. Chromosome Res. 13, 357-375.
39. Sasagawa, Y., Otani, M., Higashitani, N., Higashitani, A., Sato, K., Ogura, T. & Yamanaka, K. (2009) Caenorhabditis elegans p97 controls germline-specific sex determination by controlling the TRA-1 level in a CUL-2-dependent manner. J. Cell Sci. 122, 3663-3672.
40. Sasagawa, Y., Sato, S., Ogura, T. & Higashitani, A. (2007a) C. elegans RBX-2-CUL-5- and RBX-1-CUL-2-based complexes are redundant for oogenesis and activation of the MAP kinase MPK-1. FEBS Lett. 581, 145-150.
41. Sasagawa, Y., Urano, T., Kohara, Y., Takahashi, H. & Higashitani, A. (2003) Caenorhabditis elegans RBX1 is essential for meiosis, mitotic chromosomal condensation and segregation, and cytokinesis. Genes Cells 8, 857-872.
42. Sasagawa, Y., Yamanaka, K., Nishikori, S. & Ogura, T. (2007b) Caenorhabditis elegans p97/CDC-48 is crucial for progression of meiosis I. Biochem. Biophys. Res. Commun. 358, 920-924.
43. Sasagawa, Y., Yamanaka, K. & Ogura, T. (2007c) ER E3 ubiquitin ligase HRD-1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in Caenorhabditis elegans. Genes Cells 12, 1063-1073.
44. Schuberth, C. & Buchberger, A. (2005) Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation. Nat. Cell Biol. 7, 999-1006.
45. Schuberth, C. & Buchberger, A. (2008) UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97. Cell. Mol. Life Sci. 65, 2360-2371.
46. Schuberth, C., Richly, H., Rumpf, S. & Buchberger, A. (2004) Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation. EMBO Rep. 5, 818-824.
47. Shimada, M., Kanematsu, K., Tanaka, K., Yokosawa, H. & Kawahara, H. (2006) Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans. Mol. Biol. Cell 17, 5356-5371.
48. Song, E.J., Yim, S.H., Kim, E., Kim, N.S. & Lee, K.J. (2005) Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway. Mol. Cell. Biol. 25, 2511-2524.
49. Sonnichsen, B., Koski, L.B., Walsh, A., et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434, 462-469.
50. Starostina, N.G., Lim, J.M., Schvarzstein, M., Wells, L., Spence, A.M. & Kipreos, E.T. (2007) A CUL-2 ubiquitin ligase containing three FEM proteins degrades TRA-1 to regulate C. elegans sex determination. Mol. Cell 13, 127-139.
51. Ward, S. (1987) Expression of sperm-specific genes during nematode spermatogenesis. Ann. N.Y. Acad. Sci. 513, 128-133.
52. Woodman, P.G. (2003) p97, a protein coping with multiple identities. J. Cell Sci. 116, 4283-4290.
53. Yamanaka, K., Okubo, Y., Suzaki, T. & Ogura, T. (2004) Analysis of the two p97/VCP/Cdc48p proteins of Caenorhabditis elegans and their suppression of polyglutamine-induced protein aggregation. J. Struct. Biol. 146, 242-250.
54. Yamauchi, S., Sasagawa, Y., Ogura, T. & Yamanaka, K. (2007) Differential expression pattern of UBX family genes in Caenorhabditis elegans. Biochem. Biophys. Res. Commun. 358, 545-552.
55. Ye, Y., Meyer, H.H. & Rapoport, T.A. (2001) The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414, 652-656.
56. Ye, Y., Meyer, H.H. & Rapoport, T.A. (2003) Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J. Cell Biol. 162, 71-84.
57. Yuan, X., Simpson, P., McKeown, C., Kondo, H., Uchiyama, K., Wallis, R., Dreveny, I., Keetch, C., Zhang, X., Robinson, C., Freemont, P. & Matthews, S. (2004) Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97. EMBO J. 23, 1463-1473.
58. Zarkower, D. & Hodgkin, J. (1992) Molecular analysis of the C. elegans sex-determination gene tra-1: a gene encoding two zinc finger proteins. Cell 70, 237-249.
59. Zhao, G., Zhou, X., Wang, L., Li, G., Schindelin, H. & Lennarz, W.J. (2007) Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation. Proc. Natl Acad. Sci. USA 104, 8785-8790.