Caenorhabditis elegans Elongin BC complex is essential for cell proliferation and chromosome condensation and segregation during mitosis and meiotic division II

Chromosome Research

Volumn 13, Issue 4, 2005, Pages 357-375

  Sasagawa, Yohei ^a   Kikuchi, Koji ^a   Dazai, Kumiko ^a   Higashitani, Atsushi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Caenorhabditis; Cell cycle; cki 1; Cullin; elb 1; elc 1; Meiosis; Ubiquitin ligase

Indexed keywords

ELONGIN B; ELONGIN C;

ARTICLE; CAENORHABDITIS ELEGANS; CELL FUNCTION; CELL PROLIFERATION; CHROMOSOME CONDENSATION; CONTROLLED STUDY; GENE DELETION; MEIOSIS; MITOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; RNA ANALYSIS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL CYCLE PROTEINS; CELL DIVISION; CELL PROLIFERATION; CELL SHAPE; CHROMOSOME SEGREGATION; CYCLIN-DEPENDENT KINASE INHIBITOR PROTEINS; G1 PHASE; GERM CELLS; GONADS; INTESTINES; MEIOSIS; MULTIPROTEIN COMPLEXES; PHYLOGENY; RNA INTERFERENCE; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 20744454723     PISSN: 09673849     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10577-005-2687-5     Document Type: Article

References (45)

1. Aoki H, Sato S, Takanami T et al. (2000) Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans. Mol Gen Genet 264: 119-126.
2. Aso T, Lane WS, Conaway JW, Conaway RC (1995) Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II. Science 269: 1439-1443.
3. Bradsher JN, Jackson KW, Conaway RC, Conaway JW (1993a) RNA polymerase II transcription factor SIII. I. Identification, purification, and properties. J Biol Chem 268: 25587-25593.
4. Bradsher JN, Tan S, McLaury HJ, Conaway JW, Conaway RC (1993b) RNA polymerase II transcription factor SIII. II. Functional properties and role in RNA chain elongation. J Biol Chem 268: 25594-25603.
5. Brower CS, Shilatifard A, Mather T et al. (1999) The elongin B ubiquitin homology domain. Identification of Elongin B sequences important for interaction with Elongin C. J Biol Chem 274: 13629-13636.
6. DeRenzo C, Reese KJ, Seydoux G (2003) Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation. Nature 424: 685-689.
7. Duan DR, Pause A, Burgess WH et al. (1995) Inhibition of transcription elongation by the VHL tumor suppressor protein. Science 269: 1402-1406.
8. Feng H, Zhong W, Punkosdy G et al. (1999) CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans. Nat Cell Biol 1: 486-492.
9. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811.
10. Gonczy P, Echeverri C, Oegema K et al. (2000) Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408: 331-336.
11. Jackson T, Kwon E, Chachulska AM, Hyman LE (2000) Novel roles for elongin C in yeast. Biochim Biophys Acta 1491: 161-176.
12. Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J (2000) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol 2: RESEARCH0002 [Online].
13. Kamath RS, Fraser AG, Dong Y et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-237.
14. Kamura T, Sato S, Haque D et al. (1998) The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families. Genes Dev 12: 3872-3881.
15. Kamura T, Koepp DM, Conrad MN et al. (1999a) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284: 657-661.
16. Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW (1999b) The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2. Genes Dev 13: 2928-2933.
17. Kibel A, Iliopoulos O, DeCaprio JA, Kaelin Jr WG (1995) Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C. Science 269: 1444-1446.
18. Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM (1996) cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 85: 829-839.
19. Koth CM, Botuyan MV, Moreland RJ et al. (2000) Elongin from Saccharomyces cerevisiae. J Biol Chem 275: 11174-11180.
20. Kurz T, Pintard L, Willis JH et al. Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway. Science 295: 1294-1298.
21. Lewis JA, Fleming JT (1995) Basic culture methods. Meth Cell Biol 48: 3-29.
22. MacQueen AJ, Villeneuve AM (2001) Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2. Genes Dev 15: 1674-1687.
23. Madi A, Mikkat S, Ringel B, Thiesen HJ, Glocker MO (2003) Profiling stage-dependent changes of protein expression in Caenorhabditis elegans by mass spectrometric proteome analysis leads to the identification of stage-specific marker proteins. Electrophoresis 24: 1809-1817.
24. Maeda I, Kohara Y, Yamamoto M, Sugimoto A (2001) Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr Biol 11: 171-176.
25. Mains PE, Kemphues KJ, Sprunger SA, Sulston IA, Wood WB (1990) Mutations affecting the meiotic and mitotic divisions of the early Caenorhabditis elegans embryo. Genetics 126: 593-605.
26. Maxwell PH, Wiesener MS, Chang GW et al. (1999) The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399: 271-275.
27. Nasmyth K, Peters JM, Uhlmann F (2000) Splitting the chromosome: cutting the ties that bind sister chromatids. Science 288: 1379-1385.
28. Nayak S, Santiago FE, Jin H, Lin D, Schedl T, Kipreos ET (2002) The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis. Curr Biol 12: 277-287.
29. Ohh M, Park CW, Ivan M et al. (2000) Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat Cell Biol 2: 423-427.
30. Ohta T, Michel JJ, Schottelius AJ, Xiong Y (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3: 535-541.
31. Peters JM (1998) SCF and APC: the Yin and Yang of cell cycle regulated proteolysis. Curr Opin Cell Biol 10: 759-768.
32. Pintard L, Kurz T, Glaser S, Willis JH, Peter M, Bowerman B (2003) Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to mitosis transition in C. elegans. Curr Biol 13: 911-921.
33. Praitis V, Casey E, Collar D, Austin J (2001) Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics 157: 1217-1226.
34. Sasagawa Y, Urano T, Kohara Y, Takahashi H, Higashitani A (2003) Caenorhabditis elegans RBX1 is essential for meiosis, mitotic chromosomal condensation and segregation, and cytokinesis. Genes Cells 8: 857-872.
35. Seol JH, Feldman RM, Zachariae W et al. (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Der 13: 1614-1626.
36. Simmer F, Moorman C, Van Der Linden AM et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12
37. Skowyra D, Koepp DM, Kamura T et al. (1999) Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284: 662-665.
38. Tabara H, Grishok A, Mello CC (1998) RNAi in C. elegans: soaking in the genome sequence. Science 282: 430-431.
39. Takanami T, Sato S, Ishihara T, Katsura I, Takahashi H, Higashitani A (1998) Characterization of a Caenorhabditis elegans recA-like gene Ce-rdh-1 involved in meiotic recombination. DNA Res 5: 373-377.
40. Takanami T, Zhang Y, Aoki H et al. (2003) Efficient repair of DNA damage induced by heavy ion particles in meiotic prophase I nuclei of Caenorhabditis elegans. J Radiat Res 44: 271-276.
41. Tan P, Fuchs SY, Chen A et al. (1999) Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha. Mol Cell 3: 527-533.
42. Timmons L, Fire A (1998) Specific interference by ingested dsRNA. Nature 395:854.
43. Tyers M, Jorgensen P (2000) Proteolysis and the cell cycle: with this RING I do thee destroy. Curr Opin Genet Dev 10: 54-64.
44. Yeong FM (2004) Anaphase-promoting complex in Caenorhabilitis elegans. Mol Cell Biol 24: 2215-2225.
45. Zhong W, Feng H, Santiago FE, Kipreos ET (2003) CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing. Nature 423: 885-889.