Homocysteine, another risk factor for Alzheimer disease, impairs apolipoprotein E3 function

Journal of Biological Chemistry

Volumn 285, Issue 49, 2010, Pages 38382-38388

  Minagawa, Hirohisa ^a   Watanabe, Atsushi ^a   Akatsu, Hiroyasu ^b   Adachi, Kayo ^a   Ohtsuka, Chigumi ^c   Terayama, Yasuo ^c   Hosono, Takashi ^a   Takahashi, Satoshi ^c   Wakita, Hideaki ^a   Jung, Cha Gyun ^a   Komano, Hiroto ^c   Michikawa, Makoto ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b NAGOYA CITY UNIVERSITY   (Japan)

^c IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; APOLIPOPROTEIN E (APOE); APOLIPOPROTEINS; BRAIN HOMOGENATES; CEREBRO SPINAL FLUIDS; CONTROL SUBJECT; CYSTEINE RESIDUES; DIFFERENT RISK FACTORS; DISULFIDE BONDS; HOMOCYSTEINES; HYPERHOMOCYSTEINEMIA; RISK FACTORS; THIOL GROUPS; WESTERN-BLOT ANALYSIS;

AMINO ACIDS; OLIGOMERS;

DIMERIZATION;

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; HIGH DENSITY LIPOPROTEIN; HOMOCYSTEINE;

AGED; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL CULTURE; CHOLESTEROL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; DIMERIZATION; DISULFIDE BOND; DOSE RESPONSE; FEMALE; HUMAN; HYPERHOMOCYSTEINEMIA; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN FUNCTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RISK FACTOR; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; BRAIN; DISULFIDES; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; LIPOPROTEINS, HDL; MICE; MICE, KNOCKOUT; PROTEIN MULTIMERIZATION; RISK FACTORS;

MUS;

EID: 78649666051     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.146258     Document Type: Article

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