Oriented immobilization of prion protein demonstrated via precise interfacial nanostructure measurements

ACS Nano

Volumn 4, Issue 11, 2010, Pages 6607-6616

  Sanavio, Barbara ^a,b   Scaini, Denis ^a   Grunwald, Christian ^c   Legname, Giuseppe ^a,b,d   Scoles, Giacinto ^a,b,d   Casalis, Loredana ^a,d  

^a SINCROTRONE TRIESTE   (Italy)

^b SISSA   (Italy)

^c GOETHE UNIVERSITY   (Germany)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Atomic force microscopy; Nanografting; Prion protein; Protein immobilization; Protein orientation

Indexed keywords

BINDING PARAMETER; BIORECOGNITION; DEVICE PROPERTIES; DIAGNOSTIC APPLICATIONS; DIRECT DETECTION; DISORDERED PROTEINS; ENVIRONMENTAL PARAMETER; FOLDED PROTEINS; FUNCTIONALIZED SURFACES; HIGH SENSITIVITY; IN-SITU; LIQUID ENVIRONMENT; LOCAL ENVIRONMENTS; NANO SCALE; NANOGRAFTING; NANOPATTERNING; NANOSTRUCTURED SURFACE; PERFORMANCE OPTIMIZATIONS; PRION PROTEIN; PROTEIN IMMOBILIZATION; PROTEIN INTERACTION; PROTEIN MISFOLDING; PROTEIN NANOARRAYS; PROTEIN ORIENTATION; RECOGNITION PROCESS; REFOLDING; TIP-INDUCED; TOPOGRAPHIC MEASUREMENTS; ULTRAFLAT; ULTRASENSITIVE;

AMINO ACIDS; ATOMIC FORCE MICROSCOPY; ATOMS; MOLECULAR ORIENTATION; NANOSTRUCTURED MATERIALS;

PROTEINS;

ALKANE; ANTIBODY; GOLD; IMMOBILIZED PROTEIN; MACROGOL DERIVATIVE; NANOMATERIAL; NITRILOTRIACETIC ACID; THIOL DERIVATIVE; TRIETHYLENE GLYCOL;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGY; METHODOLOGY; MOUSE; NANOTECHNOLOGY; PRION; PROTEIN CONFORMATION; SURFACE PROPERTY;

ALKANES; ANIMALS; ANTIBODIES; GOLD; IMMOBILIZED PROTEINS; MICE; MODELS, MOLECULAR; NANOSTRUCTURES; NANOTECHNOLOGY; NITRILOTRIACETIC ACID; POLYETHYLENE GLYCOLS; PRIONS; PROTEIN CONFORMATION; SULFHYDRYL COMPOUNDS; SURFACE PROPERTIES;

EID: 78649613243     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn101872w     Document Type: Article

References (48)

1. Wingren, C.; Borrebaeck, C. A. K. Progress in Miniaturization of Protein Arrays - A Step Closer to High-Density Nanoarrays Drug. Discovery Today 2007, 12, 813-819
2. Ling, M.; Ricks, C.; Lea, P. Multiplexing Molecular Diagnostics and Immunoassays Using Emerging Microarray Technologies Expert Rev. Mol. Diagn. 2007, 7, 87-98
3. Kusnezow, W.; Syagailo, Y. V.; Goychuk, I.; Hoheisel, J. D.; Wild, D. G. Antibody Microarrays: The Crucial Impact of Mass Transport on Assay Kinetics and Sensitivity Expert Rev. Mol. Diagn. 2006, 6, 111-124
4. Fredriksson, S.; Gullberg, M.; Jarvius, J.; Olsson, C.; Pietras, K.; Gústafsdóttir, S.; östman, A.; Landegren, U. Protein Detection Using Proximity-Dependent DNA Ligation Assays Nat. Biotechnol. 2006, 20, 473-477
5. Rissin, D. M.; Kan, C. W.; Campbell, T. G.; Howes, S. C.; Fournier, D. R.; Song, L.; Piech, T.; Patel, P. P.; Chang, L.; Rivnak, A. J.; et al. Single-Molecule Enzyme-Linked Immunosorbent Assay Detects Serum Proteins at Subfemtomolar Concentrations Nat. Biotechnol. 2010, 28, 595-599
6. Sheehan, P. E.; Whitman, L. J. Detection Limits for Nanoscale Biosensors Nano Lett. 2005, 5, 803-807
7. Lee, K. B.; Park, S. J.; Mirkin, C. A.; Smith, J. C.; Mrksich, M. Protein Nanoarrays Generated by Dip-Pen Nanolithography Science 2002, 295, 1702-1705
8. Tinazli, A.; Piehler, J.; Beuttler, M.; Guckenberger, R.; Tampé, R. Native Protein Nanolithography that Can Write, Read, and Erase Nat. Nanotechnol. 2007, 2, 220-225
9. Artelsmair, H.; Kienberger, F.; Tinazli, A.; Schlapak, R.; Zhu, R.; Preiner, J.; Wruss, J.; Kastner, M.; Saucedo Zeni, N.; Hoelzl, M.; et al. Atomic Force Microscopy Derived Nanoscale Chip for the Detection of Human Pathogenic Viruses Small 2008, 4, 847-854
10. Xu, S.; Liu, G. Y. Nanometer-Scale Fabrication by Simultaneous Nanoshaving and Molecular Self-Assembly Langmuir 1997, 13, 127-129
11. Tan, Y. H.; Liu, M.; Nolting, B.; Go, J. G.; Gervay-Hague, J.; Liu, G. Y. A Nanoengineering Approach for Investigation and Regulation of Protein Immobilization ACS Nano 2008, 2, 2374-2384
12. Camarero, J. Recent Developments in the Site-Specific Immobilization of Proteins onto Solid Supports Pept. Sci. 2008, 90, 450-458
13. Polano, M.; Bek, A.; Benetti, F.; Lazzarino, M.; Legname, G. Structural Insights into Alternate Aggregated Prion Protein Forms J. Mol. Biol. 2009, 393, 1033-1042
14. Adamcik, J.; Jung, J.; Flakowski, J.; De Los Rios, P.; Dietler, G.; Mezzenga, R. Understanding Amyloid Aggregation by Statistical Analysis of Atomic Force Microscopy Images Nat. Nanotechnol. 2010, 5, 423-428
15. Cohen, F. E.; Prusiner, S. B. Pathologic Conformations of Prion Proteins Annu. Rev. Biochem. 1998, 67, 793-819
16. Prusiner, S. Prions Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 13363-13383
17. Riek, R.; Hornemann, S.; Wider, G.; Glockshuber, R.; Wüthrich, K. NMR Characterization of the Full-Length Recombinant Murine Prion Protein, mPrp(23-231) FEBS Lett. 1997, 413, 282-288 (Pubitemid 27353285)
18. Kanaani, J.; Prusiner, S. B.; Diacovo, J.; Baekkeskov, S.; Legname, G. Recombinant Prion Protein Induces Rapid Polarization and Development of Synapses in Embryonic Rat Hippocampal Neurons in Vitro J. Neurochem. 2005, 95, 1373-1386
19. Legname, G.; Baskakov, I. V.; Nguyen, H. O.; Riesner, D.; Cohen, F. E.; DeArmond, S. J.; Prusiner, S. B. Synthetic Mammalian Prions Science 2004, 305, 673-676
20. Brown, P.; Cervenáková, L.; Diringer, H. Blood Infectivity and the Prospects for a Diagnostic Screening Test in Creutzfeldt-Jakob Disease J. Lab. Clin. Med. 2001, 137, 5-13
21. Zerr, I.; Kallenberg, K.; Summers, D. M.; Romero, C.; Taratuto, A.; Heinemann, U.; Breithaupt, M.; Varges, D.; Meissner, B.; Ladogana, A.; et al. Updated Clinical Diagnostic Criteria for Sporadic Creutzfeldt-Jakob Disease Brain 2009, 132, 2659-2668
22. Huzarewich, R. L.; Siemens, C. G.; Booth, S. A. Application of "Omics" to Prion Biomarker Discovery J. Biomed. Biotechnol. 2010, 2010, 613504
23. Mirmomtaz, E.; Castronovo, M.; Grunwald, C.; Bano, F.; Scaini, D; Ensafi, A. A.; Scoles, G.; Casalis, L. Quantitative Study of the Effect of Coverage on the Hybridization Efficiency of Surface-Bound DNA Nanostructures Nano Lett. 2008, 8, 4134-4139
24. Castronovo, M.; Radovic, S.; Grunwald, C.; Casalis, L.; Morgante, M.; Scoles, G. Control of Steric Hindrance on Restriction Enzyme Reactions with Surface-Bound DNA Nanostructures Nano Lett. 2008, 8, 4140-4145
25. Staii, C.; Wood, D. W.; Scoles, G. Verification of Biochemical Activity for Proteins Nanografted on Gold Surfaces J. Am. Chem. Soc. 2008, 130, 640-646
26. Staii, C.; Wood, D. W.; Scoles, G. Ligand-Induced Structural Changes in Maltose Binding Proteins Measured by Atomic Force Microscopy Nano Lett. 2008, 8, 2503-2509
27. Bano, F.; Fruk, L.; Sanavio, B.; Glettenberg, M.; Casalis, L.; Niemeyer, C. M.; Scoles, G. Toward Multiprotein Nanoarrays Using Nanografting and DNA Directed Immobilization of Proteins Nano Lett. 2009, 9, 2614-2618
28. Ostuni, E.; Chapman, R.; Holmlin, R.; Takayama, S.; Whitesides, G. A Survey of Structure-Property Relationships of Surfaces that Resist the Adsorption of Protein Langmuir 2001, 17, 5605-5620 (Pubitemid 35330800)
29. Hochuli, E.; Döbeli, H.; Schacher, A. New Metal Chelate Adsorbent Selective for Proteins and Peptides Containing Neighbouring Histidine Residues J. Chromatogr. 1987, 411, 177-184
30. Sigal, G. B.; Bamdad, C.; Barberis, A.; Strominger, J.; Whitesides, G. M. A Self-Assembled Monolayer for the Binding and Study of Histidine-Tagged Proteins by Surface Plasmon Resonance Anal. Chem. 1996, 68, 490-497
31. Safar, J. G.; Scott, M.; Monaghan, J.; Deering, C.; Didorenko, S.; Vergara, J.; Ball, H.; Legname, G.; Leclerc, E.; Solforosi, L.; et al. Measuring Prions Causing Bovine Spongiform Encephalopathy or Chronic Wasting Disease by Immunoassays and Transgenic Mice Nat. Biotechnol. 2002, 20, 1147-1150
32. Williamson, R. A.; Peretz, D.; Pinilla, C.; Ball, H.; Bastidas, R. B.; Rozenshteyn, R.; Houghten, R. A.; Prusiner, S. B.; Burton, D. R. Mapping the Prion Protein Using Recombinant Antibodies J. Virol. 1998, 72, 9413-9418
33. Luginbühl, B.; Kanyo, Z.; Jones, R.; Fletterick, R.; Prusiner, S.; Cohen, F.; Williamson, R.; Burton, D.; Plückthun, A. Directed Evolution of an Anti-prion Protein scFv Fragment to an Affinity of 1 pM and Its Structural Interpretation J. Mol. Biol. 2006, 363, 75-97
34. Zahn, R.; Liu, A.; Lührs, T.; Riek, R.; von Schroetter, C.; López García, F.; Billeter, M.; Calzolai, L.; Wider, G.; Wüthrich, K. NMR Solution Structure of the Human Prion Protein Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 145-150 (Pubitemid 30055798)
35. CRC Handbook of Chemistry and Physics, 90th ed.; Lide, D. R., Ed.; CRC Press, Taylor and Francis: New York, 2009.
36. Valiokas, R.; Klenkar, G.; Tinazli, A.; Reichel, A.; Tampé, R.; Piehler, J.; Liedberg, B. Self-Assembled Monolayers Containing Terminal Mono-, Bis-, and Tris-Nitrilotriacetic Acid Groups: Characterization and Application Langmuir 2008, 24, 4959-4967
37. Riek, R; Hornemann, S; Wider, G; Billeter, M; Glockshuber, R; Wüthrich, K. NMR Structure of the Mouse Prion Protein Domain PrP(121-231) Nature 1996, 382, 180-182
38. Calzolai, L.; Zahn, R. Influence of pH on NMR Structure and Stability of the Human Prion Protein Globular Domain J. Biol. Chem. 2003, 278, 35592-35596 (Pubitemid 37102332)
39. Yang, T.; Baryshnikova, O. K.; Mao, H.; Holden, M. A.; Cremer, P. S. Investigations of Bivalent Antibody Binding on Fluid-Supported Phospholipid Membranes: The Effect of Hapten Density J. Am. Chem. Soc. 2003, 125, 4779-4784
40. Schwarz, G.; Stankowski, S. Linear cooperative binding of large ligands involving mutual exclusion of different binding modes Biophys. Chem. 1979, 10, 173-181
41. Kruppa, M.; Konig, B. Reversible Coordinative Bonds in Molecular Recognition Chem. Rev. 2006, 106, 3520-3560
42. Saborio, G. P.; Permanne, B.; Soto, C. Sensitive Detection of Pathological Prion Protein by Cyclic Amplification of Protein Misfolding Nature 2001, 411, 810-813
43. Kranjc, A.; Bongarzone, S.; Rossetti, G.; Biarnés, X.; Cavalli, A.; Bolognesi, M. L.; Roberti, M.; Legname, G.; Carloni, P. Docking Ligands on Protein Surfaces: The Case Study of Prion Protein J. Chem. Theory Comput. 2009, 5, 2565-2573
44. Vendruscolo, M.; Zurdo, J.; MacPhee, C. E.; Dobson, C. M. Protein Folding and Misfolding: A Paradigm of Self-Assembly and Regulation in Complex Biological Systems Philos. Trans. A 2003, 361, 1205-1222
45. Gupta, P.; Loos, K.; Korniakov, A.; Spagnoli, C.; Cowman, M.; Ulman, A. Facile Route to Ultraflat SAM-Protected Gold Surfaces by "Amphiphile Splitting" Angew. Chem., Int. Ed. 2004, 43, 520-523
46. Ulman, A. Formation and Structure of Self-Assembled Monolayers Chem. Rev. 1996, 96, 1533-1554
47. Hegner, M.; Wagner, P.; Semenza, G. Ultralarge Atomically Flat Template-Stripped Au Surfaces for Scanning Probe Microscopy Surf. Sci. 1993, 291, 36-46
48. Go, J.; Alam, M. Statistical Interpretation of "Femtomolar" Detection Appl. Phys. Lett. 2009, 95 033110