Iron deficiency - is there a role for the food industry?

International Journal of Food Science and Technology

Volumn 45, Issue 12, 2010, Pages 2443-2448

  Derbyshire, Emma ^a   Brennan, Charles S ^a   Li, Weili ^a   Bokhari, Falahat ^a  

^a MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Cost effective; Food based approaches; Fortification; Health; Iron deficiency

Indexed keywords

FOOD INDUSTRIES; FOOD-BASED APPROACHES; FORTIFICATION; IRON DEFICIENCY; NEW APPROACHES; PUBLIC SECTOR; UNDERLYING CAUSE;

COST EFFECTIVENESS; HEALTH;

HEALTH RISKS;

EID: 78649541788     PISSN: 09505423     EISSN: 13652621     Source Type: Journal    
DOI: 10.1111/j.1365-2621.2010.02431.x     Document Type: Review

References (52)

1. Ahluwalia, N. (2002) Intervention strategies for improving iron status of young children and adolescents in India. Nutrition Reviews, 60, S115-S117.
2. Allen, L.H. (2001). Biological mechanisms that might underlie iron's effects on fetal growth and preterm birth Journal of Nutrition, 131, 581S-589S.
3. Allen, L., De Benoist, B., Dary, O. & Hurrell, R. (2006). Guidelines on Food Fortification with Micronutrients. Switzerland: WHO & FAO.
4. Baltussen, R., Knai, C. & Sharan, M. (2004). Iron fortification and iron supplementation are cost-effective interventions to reduce iron deficiency in four subregions of the world. Journal of Nutrition, 134, 2678-2684.
5. Bánhidy, F., Acs, N., Puhó, E.H. & Czeizel, A.E. (2010) Iron deficiency anemia: pregnancy outcomes with or without iron supplementation. Nutrition [Epub ahead of print].
6. Bates, B., Lennox, A. & Swan, G. (2010). National Diet and Nutrition Survey Headline results from year 1 of the Rolling Programme (2008-09). London: FSA and the DH.
7. Benton, D. (2008). Micronutrient status, cognition and behavioral problems in childhood. European Journal of Nutrition, 47, 38-50.
8. Cavill, I., Auerbach, M., Bailie, G.R. et al. (2006). Iron and the anaemia of chronic disease: a review and strategic recommendation. Current Medical Research Opinions, 22, 731-737.
9. Clark, S.F. (2008). Iron deficiency anemia. Nutrition in Clinical Practice, 23, 128-141.
10. Cook, J.D. (2005). Diagnosis and management of iron-deficiency anaemia. Best Practice & Research in Clinical Haematology, 18, 319-332.
11. DH (1991). Dietary Reference Values for food Energy and Nutrients for the United Kingdom, 2nd edition. Report on Social Subjects no. 41. The Stationary Office: London.
12. EFSA (European Food Safety Authority) (2006). "Tolerable Upper Intake levels of vitamins and minerals by the Scientific Panel on Dietetic products, nutrition and allergies (NDA) and Scientific Committee on Food (SCF)". Available at: (accessed June 2010).
13. EFSA (European Food Safety Authority) (2009a). Scientific Opinion on the Substantiation of a health claim related to Iron and cognitive development of children pursuant to Article 14 of regulation (EC) No 1924/2006. EFSA Journal, 7, 1360.
14. EFSA (European Food Safety Authority) (2009b). Scientific Opinion on the substantiation of health claims related to iron and formation of red blood cells and haemoglobin (ID 249, ID 1589), oxygen transport (ID 250, ID 254, ID 256), energy-yielding metabolism (ID 251, ID 1589), function of the immune system (ID 252, ID 259), cognitive function (ID 253) and cell division (ID 368) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal, 7, 1215.
15. European Commission (2008). "Amending Directive 90/496/EEC of the Council as regards recommended daily allowances, energy conversion factors and definitions: Draft". Available at: (accessed June 2010).
16. Fairweather-Tait, S.J. (2004). Iron nutrition in the UK: getting the balance right. Proceedings of the Nutrition Society, 63, 519-528.
17. Falkingham, M., Abdelhamid, A., Curtis, P., Fairweather-Tait, S., Dye, L. & Hooper, L. (2010). The effects of oral iron supplementation on cognition in older children and adults: a systematic review and meta-analysis. Nutrition Journal, 9, 4.
18. Gautam, C.S., Saha, L., Sekhri, K. & Saha, P.K. (2008). Iron deficiency in pregnancy and the rationality of iron supplements prescribed during pregnancy. The Medscape Journal of Medicine, 10, 283.
19. Gibson, R.S., Perlas, L. & Hotz, C. (2006). Improving the bioavailability of nutrients in plant foods at the household level. Proceedings of the Nutrition Society, 65, 160-168.
20. Habib, F., Alabdin, E.H., Alenazy, M. & Nooh, R. (2009). Compliance to iron supplementation during pregnancy. Obstetrics & Gynaecology, 29, 487-492.
21. Hunt, J.R. (2003). Bioavailability of iron, zinc, and other trace minerals from vegetarian diets. American Journal of Clinical Nutrition, 78, 633S-639S.
22. Hurrell, R.F. (2002). How to ensure adequate iron absorption from iron-fortified food. Nutrition Reviews, 60, S7-S15.
23. Hurrell, R.F. (2004). Phytic acid degradation as a means of improving iron absorption. International Journal of Vitamin & Nutrition Research, 74, 445-452.
24. Jones, O.J. & Varady, K.A. (2007). Are functional foods redefining nutritional requirements? Applied Physiology, Nutrition & Metabolism, 33, 118-123.
25. Kalaivani, K. (2009). Prevalence & consequences of anaemia in pregnancy. Indian Journal of Medical Research, 130, 627-633.
26. Kehoe, S.H., Chheda, P.S., Sahariah, S.A., Baird, J. & Fall, C.H.D. (2009). Reporting of participant compliance in randomised controlled trials of nutrition supplements during pregnancy. Maternal & Child Nutrition, 5, 97-103.
27. López, M.A. & Martos, F.C. (2004). Iron availability: an updated review. International Journal of Food Sciences & Nutrition, 55, 597-606.
28. Lynch, S.R. (2005). The impact of iron fortification on nutritional anaemia. Best Practice in Research & Clinical Haematology, 18, 333-346.
29. Mannar, M.G. (2006). Successful food-based programmes, supplementation and fortification. Journal of Pediatric Gastroenterology & Nutrition, 43, S47-S53.
30. Mannar, M.G. & Sankar, R. (2004). Micronutrient fortification of foods - rationale, application and impact. Indian Journal of Paediatrics, 71, 997-1002.
31. Mannar, M.G. & Van Ameringen, M. (2003). Role of public-private partnership in micronutrient food fortification. Food & Nutrition Bulletin, 24, S151-S154.
32. Meyer, A.S. (2010). Enzyme technology for precision functional food ingredient processes. Annals of the New York Academy of Sciences, 1190, 126-132.
33. Nelson, M., Erens, B., Bates, B. et al. (2007). Low Income Diet and Nutrition Survey. Three Volume Survey, Executive Summary. London: The Stationary Office.
34. Ortiz-Andrellucchi, A., Henriquez-Sanchez, P., Sanchez-Villegas, A., Pena-Quintana, L., Mendez, M. & Serra-Majem, L. (2009). Dietary assessment methods for micronutrient intake in infants, children and adolescents: a systemic review. British Journal of Nutrition, 102, S87-S117.
35. Patel, K.V. (2008). Epidemiology of anemia in older adults. Seminars in Haematology, 45, 210-217.
36. Patterson, A.J., Brown, W.J., Roberts, D.C.K. & Seldon, M.R. (2001). Dietary treatment of iron deficiency in women of childbearing age. American Journal of Clinical Nutrition, 74, 650-656.
37. Ruston, D., Hoare, J., Henderson, L. et al. (2004). National Diet and Nutrition Survey: adults aged 19 to 64 years. Volume 4: Nutritional status (anthropometry and blood analytes), blood pressure and physical activity. London: The Stationary Office.
38. Salim, U.R., Huma, N., Tarar, O.M. & Shah, W.H. (2010). Efficacy of non-heme iron fortified diets: a review. Critical Reviews in Food Science & Nutrition, 50, 403-413.
39. Schümann, K. (2001). Safety aspects of iron in food. Annals of Nutrition & Metabolism, 45, 91-101.
40. Scientific Advisory Committee on Nutrition (SACN) (2009). Draft SACN Report on Iron and Health. London: The Stationary Office.
41. Stein, A.J., Meenakshi, J.V., Qaim, M., Nestel, P., Sachdev, H.P. & Bhutta, Z.A. (2008). Potential impacts of iron biofortification in India. Social Science & Medicine, 66, 1797-1808.
42. Suedekum, N.A. & Dimeff, R.J. (2005). Iron and the athlete. Current Sports Medicine Reports, 4, 199-202.
43. Sungthong, R., Mo-suwan, L. & Chongsuvivatwong, V. (2002). Effects of haemoglobin and serum ferritin on cognitive function in school children. Asia Pacific Journal of Clinical Nutrition, 11, 117-122.
44. Thomas, D.G., Grant, S.L. & Aubuchon- Endsley, N.L. (2009). The role of iron in neurocognitive development. Developmental Neuropsychology, 34, 196-222.
45. Tontisirin, K., Nantel, G. & Bhattacharjee, L. (2002). Food-based strategies to meet the challenges of micronutrient malnutrition in the developing world. Proceedings of the Nutrition Society, 61, 243-250.
46. Uauy, R., Hertrampf, E. & Reddy, M. (2002). Iron fortification of foods: overcoming technical and practical barriers. Journal of Nutrition, 132, 849S-852S.
47. Van Puyvelde, K., Cytryn, E., Mets, T. & Beyer, I. (2009). Anaemia in the elderly. Acta Clinica Belgica, 64, 292-302.
48. Villar, J., Merialdi, M., Gulmezoglu, A.M. et al. (2003). Nutritional interventions during pregnancy for the prevention or treatment of maternal morbidity and preterm delivery: an overview of randomised controlled trials. Journal of Nutrition, 133, 160S-1625S.
49. Walter, T. (2003). Effect of iron-deficiency anemia on cognitive skills and neuromaturation in infancy and childhood. Food & Nutrition Bulletin, 24, S104-S110.
50. WHO/UNICEF/ICCIDD (2001). Iron Deficiency Anemia: Assessment, Prevention and Control. Switzerland: World Health Organisation.
51. World Health Organisation (WHO) (2008). Worldwide Prevalence of Anaemia 1993-2005: WHO Global Database on Anaemia. Geneva, Switzerland.
52. Zimmermann, M.B. (2008). Methods to assess iron and iodine status. British Journal of Nutrition, 99, S2-S9.