Silencing of PTK7 in colon cancer cells: Caspase-10-dependent apoptosis via mitochondrial pathway

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Meng, Ling ^a   Sefah, Kwame ^a   O'Donoghue, Meghan B ^a   Zhu, Guizhi ^a   Shangguan, Dihua ^a   Noorali, Afshan ^a   Chen, Yan ^a   Zhou, Lei ^a   Tan, Weihong ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 10; CASPASE 10 INHIBITOR; CASPASE 9; CASPASE INHIBITOR; MESSENGER RNA; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE 7; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; PROTEIN P53; PTK7 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL PROLIFERATION; CELL STRAIN HCT116; COLON CARCINOMA; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; CELL SURVIVAL; COLON TUMOR; ENZYMOLOGY; FLOW CYTOMETRY; GENETICS; METABOLISM; MITOCHONDRION; MUTATION; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CASPASE 10; CASPASE 9; CELL ADHESION MOLECULES; CELL PROLIFERATION; CELL SURVIVAL; COLONIC NEOPLASMS; ENZYME ACTIVATION; FLOW CYTOMETRY; HCT116 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MUTATION; RECEPTOR PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78649515069     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014018     Document Type: Article

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