Collaborative work on evaluation of ovarian toxicity 8) Two- or four-week repeated-dose studies and fertility study of Anastrozole in female rats

Journal of Toxicological Sciences

Volumn 34, Issue 1 SPEC. ISS., 2009, Pages

  Shirai, Makoto ^a   Sakurai, Ken ^a   Saitoh, Wataru ^a   Matsuyama, Takuya ^a   Teranishi, Munehiro ^a   Furukawa, Tadashi ^a   Sanbuissho, Atsushi ^a   Manabe, Sunao ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Anastrozole; Aromatase inhibitor; Atresia; Follicular cyst; Ovarian toxicity; Pathology

Indexed keywords

ANASTROZOLE; AROMATASE INHIBITOR; NITRILE; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORPUS LUTEUM; ESTRUS CYCLE; FEMALE; FEMALE FERTILITY; FOLLICLE CYST; HISTOPATHOLOGY; MALE; MATING; MORPHOLOGY; NONHUMAN; OVARY; OVARY FOLLICLE ATRESIA; PREGNANCY; PREGNANCY RATE; RAT; REPRODUCTIVE TOXICITY; ANIMAL; BODY WEIGHT; DRUG ADMINISTRATION; DRUG EFFECT; FERTILITY; FISCHER 344 RAT; GERMFREE ANIMAL; HEALTH CARE ORGANIZATION; JAPAN; METABOLISM; METHODOLOGY; ORGAN SIZE; OVARY FOLLICLE; PATHOLOGY; TOXICITY TESTING; UTERUS;

RATTUS;

ANIMALS; AROMATASE INHIBITORS; BODY WEIGHT; CORPUS LUTEUM; DRUG ADMINISTRATION SCHEDULE; ESTROUS CYCLE; FEMALE; FERTILITY; JAPAN; MALE; NITRILES; ORGAN SIZE; OVARIAN FOLLICLE; OVARY; PREGNANCY; PUBLIC-PRIVATE SECTOR PARTNERSHIPS; RATS; RATS, INBRED F344; SOCIETIES, SCIENTIFIC; SPECIFIC PATHOGEN-FREE ORGANISMS; TOXICITY TESTS; TRIAZOLES; UTERUS;

EID: 64949113360     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.34.s91     Document Type: Article

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