Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle

Osteoarthritis and Cartilage

Volumn 13, Issue 4, 2005, Pages 318-329

  Hoemann, Caroline D ^a   Sun, J ^b   Legare A ^b   McKee, M D ^c   Buschmann, M D ^a  

^a ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

^b Biosyntech Inc   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Cartilage; Chitosan; Hydrogel; Implants; Rabbit model; Tissue engineering

Indexed keywords

AGAROSE; CHITOSAN; COLLAGEN; DNA; GLYCOSAMINOGLYCAN; MESSENGER RNA; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHROSCOPY; ARTICLE; ARTICULAR CARTILAGE; BIOCHEMISTRY; BIOCOMPATIBILITY; BIOMECHANICS; BONE TISSUE; CARTILAGE CELL; CARTILAGE DEGENERATION; CARTILAGE MATRIX; CELL ADHESION; CHONDROGENESIS; CONTROLLED STUDY; GENE EXPRESSION; HISTOCHEMISTRY; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; TISSUE ENGINEERING; TISSUE REPAIR;

ADHESIONS; ANIMALS; BIOCOMPATIBLE MATERIALS; BIOMECHANICS; CARTILAGE, ARTICULAR; CATTLE; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CHITOSAN; CHONDROCYTES; HYDROGEL; INJECTIONS, INTRALESIONAL; MICE; MICE, NUDE; PATELLA; RABBITS; TISSUE ENGINEERING;

EID: 14944380686     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2004.12.001     Document Type: Article

References (53)

1. T. Hardingham S. Tew A. Murdoch Tissue engineering: Chondrocytes and cartilage Arthritis Res 4 Suppl 3 2002 S63-S68
2. E.B. Hunziker Articular cartilage repair: Basic science and clinical progress. A review of the current status and prospects Osteoarthritis Cartilage 10 6 2002 432-463
3. M. Brittberg A. Lindahl A. Nilsson C. Ohlsson O. Isaksson L. Peterson Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation N Engl J Med 331 1994 889-895
4. D.A. Grande M.I. Pitman L. Peterson D. Menche M. Klein The repair of experimentally produced defects in rabbit articular cartilage by autologous chondrocyte transplantation J Orthop Res 7 2 1989 208-218
5. D. Passaretti R.P. Silverman W. Huang C.H. Kirchhoff S. Ashiku M.A. Randolph et al. Cultured chondrocytes produce injectable tissue-engineered cartilage in hydrogel polymer Tissue Eng 7 2001 805-815
6. M. Brittberg A. Nilsson A. Lindahl C. Ohlsson L. Peterson Rabbit articular cartilage defects treated with autologous cultured chondrocytes Clin Orthop 326 1996 270-283
7. F. Dell'Accio C. De Bari F.P. Luyten Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo Arthritis Rheum 44 2001 1608-1619
8. J.M. Lipman C.A. McDevitt L. Sokoloff Xenografts of articular chondrocytes in the nude mouse Calcif Tissue Int 35 6 1983 767-772
9. T. Kimura N. Yasui S. Ohsawa K. Ono Chondrocytes embedded in collagen gels maintain cartilage phenotype during long-term cultures Clin Orthop 186 1984 231-239
10. S. Nehrer H.A. Breinan A. Ramappa S. Shortkroff G. Young T. Minas et al. Canine chondrocytes seeded in type I and type II collagen implants investigated in vitro [published erratum appears in J Biomed Mater Res 1997; 38(4) 288] J Biomed Mater Res 38 2 1997 95-104
11. M.D. Buschmann Y.A. Gluzband A.J. Grodzinsky J.H. Kimura E.B. Hunziker Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix J Orthop Res 10 1992 745-758
12. L.E. Freed J.C. Marquis A. Nohria J. Emmanual A.G. Mikos R. Langer Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers J Biomed Mater Res 27 1993 11-23
13. H.J. Hauselmann M.B. Aydelotte B.L. Schumacher K.E. Kuettner S.H. Gitelis E.J. Thonar Synthesis and turnover of proteoglycans by human and bovine adult articular chondrocytes cultured in alginate beads Matrix 12 2 1992 116-129
14. L.A. Fortier A.J. Nixon H.O. Mohammed G. Lust Altered biological activity of equine chondrocytes cultured in a three-dimensional fibrin matrix and supplemented with transforming growth factor beta-1 Am J Vet Res 58 1997 66-70
15. S.J. Bryant K.S. Anseth Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels J Biomed Mater Res 59 2001 63-72
16. J. Kisiday M. Jin B. Kurz H. Hung C. Semino S. Zhang et al. Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair Proc Natl Acad Sci U S A 99 2002 9996-10001
17. C.A. Vacanti R. Langer B. Schloo J.P. Vacanti Synthetic polymers seeded with chondrocytes provide a template for new cartilage formation Plast Reconstr Surg 88 5 1991 753-759
18. K.T. Paige L.G. Cima M.J. Yaremchuk B.L. Schloo J.P. Vacanti C.A. Vacanti De novo cartilage generation using calcium alginate-chondrocyte constructs Plast Reconstr Surg 97 1 1996 168-178
19. S.C. Chang J.A. Rowley G. Tobias N.G. Genes A.K. Roy D.J. Mooney et al. Injection molding of chondrocyte/alginate constructs in the shape of facial implants J Biomed Mater Res 55 2001 503-511
20. J. Elisseeff K. Anseth D. Sims W. McIntosh M. Randolph M. Yaremchuk et al. Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage Plast Reconstr Surg 104 1999 1014-1022
21. A.B. Saim Y. Cao Y. Weng C.N. Chang M.A. Vacanti C.A. Vacanti et al. Engineering autogenous cartilage in the shape of a helix using an injectable hydrogel scaffold Laryngoscope 110 2000 1694-1697
22. C.D. Sims P.E.M. Butler R. Casanova B.T. Lee M.A. Randolph W.P.A. Lee et al. Injectable cartilage using polyethylene oxide polymer substrates Plast Reconstr Surg 98 5 1996 843-850
23. S. Wakitani T. Kimura A. Hirooka T. Ochi M. Yoneda H. Owaki et al. Repair of rabbit articular surfaces with allografts of chondrocytes embedded in collagen gels Nippon Seikeigeka Gakkai Zasshi - J Japanese Orthop Assoc 63 5 1989 529-538
24. L.E. Freed D.A. Grande Z. Lingbin J. Emmanual J.C. Marquis R. Langer Joint resurfacing using allograft chondrocytes and synthetic biodegradable polymer scaffolds J Biomed Mater Res 28 8 1994 891-899
25. R.A. Kandel H. Chen J. Clark R. Renlund Transplantation of cartilagenous tissue generated in vitro into articular joint defects Artif Cells Blood Substit Immobil Biotechnol 23 5 1995 565-577
26. L.A. Solchaga J.U. Yoo M. Lundberg J.E. Dennis B.A. Huibregtse V.M. Goldberg et al. Hyaluronan-based polymers in the treatment of osteochondral defects J Orthop Res 18 2000 773-780
27. S. Nehrer H.A. Breinan A. Ramappa H.P. Hsu T. Minas S. Shortkroff et al. Chondrocyte-seeded collagen matrices implanted in a chondral defect in a canine model Biomaterials 19 24 1998 2313-2328
28. A.J. Nixon L.A. Fortier J. Williams H. Mohammed Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites J Orthop Res 17 1999 475-487
29. H.A. Breinan S.D. Martin H.P. Hsu M. Spector Healing of canine articular cartilage defects treated with microfracture, a type-II collagen matrix, or cultured autologous chondrocytes J Orthop Res 18 2000 781-789
30. K. Jurgensen D. Aeschlimann V. Cavin M. Genge E.B. Hunziker A new biological glue for cartilage-cartilage interfaces - tissue transglutaminase J Bone Joint Surg [Am] 79A 2 1997 185-193
31. A.E. Sams A.J. Nixon Chondrocyte-laden collagen scaffolds for resurfacing extensive articular cartilage defects Osteoarthritis Cartilage 3 1 1995 47-59
32. I.M. Driesang E.B. Hunziker Delamination rates of tissue flaps used in articular cartilage repair J Orthop Res 18 2000 909-911
33. A. Chenite C. Chaput D. Wang C. Combes M.D. Buschmann C.D. Hoemann et al. Novel injectable neutral solutions of chitosan form biodegradable gels in situ Biomaterials 21 2000 2155-2161
34. C. Hoemann J. Sun A. Légaré M. McKee P. Ranger M.D. Buschmann A thermosensitive polysaccharide gel for cell delivery in cartilage repair Trans Orthop Res Soc 26 2001 626
35. C.D. Hoemann J. Sun V. Chrzanowski M.D. Buschmann A multivalent assay to detect glycosaminoglycan, protein, collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage Anal Biochem 300 2002 1-10
36. P. Sorlier A. Denuzičre C. Viton A. Domard Relation between the degree of acetylation and the electrostatic properties of chitin and chitosan Biomacromolecules 2 2001 765-772
37. P.J. VandeVord H.W. Matthew S.P. DeSilva L. Mayton B. Wu P.H. Wooley Evaluation of the biocompatibility of a chitosan scaffold in mice J Biomed Mater Res 59 2002 585-590
38. P. Sorlier D.J. Hartmann A. Denuziere C. Viton A. Domard Preparation and development of anti-chitosan antibodies J Biomed Mater Res 67A 2003 766-774
39. J. Dumont M. Ionescu A. Reiner A.R. Poole N. Tran-Khanh C.D. Hoemann et al. Mature full-thickness articular cartilage explants attached to bone are physiologically stable over long-term culture in serum-free media Connect Tissue Res 40 1999 259-272
40. Y.J. Kim R.L. Sah J.Y. Doong A.J. Grodzinsky Fluorometric assay of DNA in cartilage explants using Hoechst 33258 Anal Biochem 174 1 1988 168-176
41. M.C. Burleigh A.J. Barrett G.S. Lazarus A lysosomal enzyme that degrades native collagen Biochem J 137 1974 387-398
42. J. Soulhat M.D. Buschmann A. Shirazi-Adl A fibril-network-reinforced biphasic model of cartilage in unconfined compression J Biomech Eng 121 1999 340-347
43. P.R. Klokkevold D.S. Lew D.G. Ellis C.N. Bertolami Effect of chitosan on lingual hemostasis in rabbits J Oral Maxillofac Surg 49 1991 858-863
44. A. Chenite M. Buschmann D. Wang C. Chaput N. Kandani Rheological characterisation of thermogelling chitosan/glycerol-phosphate solutions Carbohydr Polym 46 2001 39-47
45. V.F. Sechriest Y.J. Miao C. Niyibizi A. Westerhausen-Larson H.W. Matthew C.H. Evans et al. GAG-augmented polysaccharide hydrogel: A novel biocompatible and biodegradable material to support chondrogenesis J Biomed Mater Res 49 2000 534-541
46. E. Fragonas M. Valente M. Pozzi-Mucelli R. Toffanin R. Rizzo F. Silvestri et al. Articular cartilage repair in rabbits by using suspensions of allogenic chondrocytes in alginate Biomaterials 21 2000 795-801
47. E. Khor L.Y. Lim Implantable applications of chitin and chitosan Biomaterials 24 2003 2339-2349
48. G. Vunjak-Novakovic I. Martin B. Obradovic S. Treppo A.J. Grodzinsky R. Langer et al. Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage J Orthop Res 17 1 1999 130-138
49. G.N. Homminga P. Buma H.W. Koot P.M. van der Kraan W.B. van den Berg Chondrocyte behavior in fibrin glue in vitro Acta Orthop Scand 64 4 1993 441-445
50. D.A. Grande C. Halberstadt G. Naughton R. Schwartz R. Manji Evaluation of matrix scaffolds for tissue engineering of articular cartilage grafts J Biomed Mater Res 34 1997 211-220
51. N. Rotter L.J. Bonassar G. Tobias M. Lebl A.K. Roy C.A. Vacanti Age dependence of biochemical and biomechanical properties of tissue-engineered human septal cartilage Biomaterials 23 2002 3087-3094
52. F. Shapiro S. Koide M.J. Glimcher Cell origin and differentiation in the repair of full-thickness defects of articular cartilage J Bone Joint Surg [Am] 75A 4 1993 532-553
53. M. Fortin J. Soulhat A. Shirazi-Adl E.B. Hunziker M.D. Buschmann Unconfined compression of articular cartilage: Nonlinear behavior and comparison with a fibril-reinforced biphastic model J Biomech Eng 122 2000 1-6