Low oxygen tension stimulates the redifferentiation of dedifferentiate adult human nasal chondrocytes

Osteoarthritis and Cartilage

Volumn 12, Issue 4, 2004, Pages 306-313

  Malda, J ^a,b,c   van Blitterswijk, C A ^a,b   van Geffen, M ^a,c   Martens, D E ^c   Tramper, J ^c   Riesle, Jens ^a  

^a IsoTis BV   (Netherlands)

^b UNIVERSITY OF TWENTE   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Dedifferentiation; Nasal septum chondrocytes; Oxygen tension; Redifferentiation

Indexed keywords

CELL MEMBRANE MARKER; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGEN TYPE 9; DISSOLVED OXYGEN; DNA; DYE; GLYCOSAMINOGLYCAN;

ADULT; AGED; ARTICLE; BIOREACTOR; CARTILAGE CELL; CASE REPORT; CELL DIFFERENTIATION; CELL ISOLATION; CELL MEMBRANE; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; DNA CONTENT; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; INCUBATION TIME; LIQUID; MONOLAYER CULTURE; OXYGEN TENSION; PRIORITY JOURNAL; SPECTROPHOTOMETRY; STAINING; TISSUE ENGINEERING;

EID: 1842788540     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2003.12.001     Document Type: Article

References (44)

1. Hunter W. Of the structure and disease of the articulating cartilages. Roy Soc London, Phil Trans 1743;9:267-71.
2. Mankin HJ. The reaction of articular cartilage to injury and osteoarthritis (first of two parts). N Engl J Med 1974;291:1285-92.
3. Hunziker EB, Rosenberg LC. Repair of partial-thickness defects in articular cartilage: Cell recruitment from the synovial membrane. J Bone Joint Surg Am 1996;78:721-33.
4. Buckwalter JA, Mankin HJ. Instructional Course Lectures, The American Academy of Orthopaedic Surgeons-Articular Cartilage. Part II: Degeneration and Osteoarthrosis, Repair, Regeneration, and Transplantation. J Bone Joint Surg Am 1997;79: 612-32.
5. Glowacki J. In vitro engineering of cartilage. J Rehabil Res Dev 2000;37:171-7.
6. Kawabe N, Yoshinao M. The repair of full-thickness articular cartilage defects. Immune responses to reparative tissue formed by allogeneic growth plate chondrocyte implants. Clin Orthop 1991;268:279-93.
7. Bujia J, Wilmes E, Kastenbauer E, Gurtler L. Influence of chemical allograft preservation procedures on the human immunodeficiency virus. Laryngoscope 1996; 106:645-7.
8. Kafienah WZ, Jacob M, Démarteau O, Frazer A, Barker MD, Martin I, et al. Three dimensional tissue engineering of hyaline cartilage: Comparison of adult nasal and articular chondrocytes. Tissue Eng 2002; 8:817-26.
9. Crawford A, Frazer A, Fraser S, Dickinson S, Hollander AP, Hatton PV. A comparative study of nasal and articular chondrocytes for cartilage tissue engineering. Trans Int Cartilage repair Soc 2002; 4:131.
10. Watt FM. Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture. J Cell Sci 1988;89:373-8.
11. Benya PD, Shaffer JD. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 1982;30:215-24.
12. von der Mark K, Gauss V, von der Mark H, Muller P. Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature 1977;267:531-2.
13. Brighton CT, Heppenstall RB. Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits. J Bone Joint Surg Am 1971;53:719-28.
14. Malda J, Martens DE, Riesle J, Tramper J, van Blitterswijk CA. Cartilage tissue engineering: Controversy in the effect of oxygen. Crit Rev Biotech 2003; 23:175-94.
15. Bassett CAL, Herrmann I. Influence of oxygen concentration and mechanical factors on differentiation of connective tissues in vitro. Nature 1961;190:460-1.
16. Pawelek JM. Effects of thyroxine and low oxygen tension on chondrogenic expression in cell culture. Dev Biol 1969;19:52-72.
17. Rajpurohit R, Koch CJ, Tao Z, Teixeira CM, Shapiro IM. Adaptation of chondrocytes to low oxygen tension: Relationship between hypoxia and cellular metabolism. J Cell Physiol 1996;168:424-32.
18. Silver IA. Measurement of pH and ionic composition of pericellular sites. Philos Trans R Soc Lond B Biol Sci 1975;271:261-72.
19. Brighton CT, Heppenstall RB. Oxygen tension of the epiphyseal plate distal to an arteriovenous fistula. Clin Orthop 1971;80:167-73.
20. Domm C, Schunke M, Christesen K, Kurz B. Redifferentiation of dedifferentiated bovine articular chondrocytes in alginate culture under low oxygen tension. Osteoarthritis Cart 2002;10:13-22.
21. Murphy CL, Sambanis A. Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes. Tissue Eng 2001;7:791-803.
22. Hansen U, Schunke M, Domm C, Ioannidis N, Hassenpflug J, Gehrke T, et al. Combination of reduced oxygen tension and intermittent hydrostatic pressure: A useful tool in articular cartilage tissue engineering. J Biomech 2001;34:941-9.
23. Brighton CT, Lane JM, Koh JK. In vitro rabbit articular cartilage organ model. II. 35S incorporation in various oxygen tensions. Arthritis Rheum 1974;17:245-52.
24. Ysart GE, Mason RM. Responses of articular cartilage explant cultures to different oxygen tensions. Biochim Biophys Acta 1994;1221:15-20.
25. Clark CC, Tolin BS, Brighton CT. The effect of oxygen tension on proteoglycan synthesis and aggregation in mammalian growth plate chondrocytes. J Orthop Res 1991;9:477-84.
26. Obradovic B, Carrier RL, Vunjak-Novakovic G, Freed LE. Gas exchange is essential for bioreactor cultivation of tissue engineered cartilage. Biotechnol Bioeng 1999;63:197-205.
27. Grimshaw MJ, Mason RM. Modulation of bovine articular chondrocyte gene expression in vitro by oxygen tension. Osteoarthritis Cart 2001;9:357-64.
28. Grimshaw MJ, Mason RM. Bovine articular chondrocyte function in vitro depends upon oxygen tension. Osteoarthritis Cart 2000;8:386-92.
29. Mason RM, Sweeney C. The relationship between proteoglycan synthesis in Swarm chondrocytes and pathways of cellular energy and UDP-sugar metabolism. Carbohydr Res 1994;255:255-70.
30. Hwang PM, Byrne DH, Kitos PA. Effects of molecular oxygen on chick limb bud chondrogenesis. Differentiation 1988;37:14-9.
31. Jacoby RK, Jayson MI. Organ culture of adult human articular cartilage. I. The effect of hyperoxia on synthesis of glycosaminoglycan. J Rheumatol 1975; 2:270-9.
32. Tokuda Y, Crane S, Yamaguchi Y, Zhou L, Falanga V. The levels and kinetics of oxygen tension detectable at the surface of human dermal fibroblast cultures. J Cell Physiol 2000;182:414-20.
33. Kato Y, Iwamoto M, Koike T, Suzuki F, Takano Y. Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: Regulation by transforming growth factor beta and serum factors. Proc Natl Acad Sci USA 1988; 85:9552-6.
34. Osch van GJ, Veen van der SW, Marijnissen WJ, Verhaar JA. Monoclonal antibody 11-fibrau: A useful marker to characterize chondrocyte differentiation stage. Biochem Biophys Res Commun 2001;280: 806-12.
35. Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986;883:173-7.
36. Benya PD, Padilla SR, Nimni ME. Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture. Cell 1978; 15:1313-21.
37. Benya PD, Padilla SR, Nimni ME. The progeny of rabbit articular chondrocytes synthesize collagen types I and III and type I trimer, but not type II. Verifications by cyanogen bromide peptide analysis. Biochemistry 1977;16:865-72.
38. Mandl EW, Veen van der SW, Verhaar JA, Osch van GJ. Serum-Free Medium Supplemented with High-Concentration FGF2 for Cell Expansion Culture of Human Ear Chondrocytes Promotes Redifferentiation Capacity. Tissue Eng 2002;8:573-80.
39. Nevo Z, Beit-Or A, Eilam Y. Slowing down aging of cultured embryonal chick chondrocytes by maintenance under lowered oxygen tension. Mech Ageing Dev 1988;45:157-65.
40. Malda, J, Rouwkema, J, le Comte, P, Riesle, J, Martens, DE, Tramper, J, et al. Oxygen gradients in tissue engineered PEGT/PBT constructs: Measured and modeled. Biotechnol Bioeng, in press.
41. Kellner K, Liebsch G, Klimant I, Wolfbeis OS, Blunk T, Schulz MB, et al. Determination of oxygen gradients in engineered tissue using a fluorescent sensor. Biotechnol Bioeng 2002;80:73-83.
42. Domm C, Fay J, Schunke M, Kurz B. Redifferentiation of dedifferentiated joint cartilage cells in alginate culture. Effect of intermittent hydrostatic pressure and low oxygen partial pressure. Orthopade 2000;29: 91-9.
43. Malda J, le Comte P, Riesle J, van Blitterswijk CA. Determination of oxygen gradients in tissue engineered cartilage constructs. Proc Europ Soc Biomat 2001;16:142.
44. Revsbech NP, Ward MW. Oxygen microelectrode that is insensitive to medium chemical composition: Use in an acid microbial mat dominated by Cyanidium caldarium. App Envir Microbiol 1983;45:755-9.