Anthocyanins are novel AMPKα1 stimulators that suppress tumor growth by inhibiting mTOR phosphorylation

Oncology Reports

Volumn 24, Issue 6, 2010, Pages 1471-1477

  Lee, Yun Kyoung ^a   Lee, Won Sup ^b   Kim, Gon Sup ^c   Park, Ock Jin ^a  

^a Hannam University Daedeok Valley Campus ^*  (South Korea)

^b Gyeongsang National University School of Medicine   (South Korea)

^c Gyeongsang National University   (South Korea)

Author keywords

AMP activated protein kinase; Anthocyanins; Apoptosis; Colon cancer; mTOR

Indexed keywords

AMP ACTIVATED PROTEIN KINASE ALPHA1; ANTHOCYANIN; BETA ACTIN; ELONGATION FACTOR 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; TUBEROUS SCLEROSIS COMPLEX; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER MODEL; CELL PROLIFERATION; CELL STRAIN HT29; COLON CANCER; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTHOCYANINS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DOWN-REGULATION; ENZYME ACTIVATION; HT29 CELLS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS; PHOSPHORYLATION; TOR SERINE-THREONINE KINASES; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 78649392683     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00001007     Document Type: Article

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