Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK

International Journal of Oncology

Volumn 35, Issue 6, 2009, Pages 1499-1504

  Shin, Dong Yeok ^a,b   Lee, Won Sup ^c   Lu, Jing Nan ^c   Kang, Myung Hee ^c   Ryu, Chung Ho ^d   Kim, Gi Young ^e   Kang, Ho Sung ^f   Shin, Sung Chul ^d   Choi, Yung Hyun ^a,b  

^a Dong Eui University   (South Korea)

^b Dong Eui University   (South Korea)

^c Gyeongsang National University School of Medicine   (South Korea)

^d Gyeongsang National University   (South Korea)

^e Jeju National University   (South Korea)

^f Pusan National University   (South Korea)

Author keywords

Akt; Anthocyanins; Apoptosis; Colon cancer; p38 MAPK

Indexed keywords

ANTHOCYANIN; CASPASE; INHIBITOR OF APOPTOSIS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; ANTINEOPLASTIC AGENT; PLANT EXTRACT;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STRAIN HCT116; CELL VIABILITY; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; GRAPE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; VITIS COIGNETIAE PULLIAT; CHEMISTRY; COLON TUMOR; FLOW CYTOMETRY; METABOLISM; WESTERN BLOTTING;

ANTHOCYANINS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; COLONIC NEOPLASMS; ENZYME ACTIVATION; FLOW CYTOMETRY; HCT116 CELLS; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; VITIS;

EID: 73949087599     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000469     Document Type: Article

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