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Volumn 1, Issue 2, 2010, Pages 289-305

Overcoming the challenges in the effective delivery of chemotherapies to CNS solid tumors

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CATION; DENDRIMER; DOXORUBICIN; GADOLINIUM PENTETATE; LIPID; LIPOSOME; LOBRADIMIL; LOMUSTINE; NANOPARTICLE; RHODAMINE B; TEMOZOLOMIDE; VINBLASTINE; VINCRISTINE;

EID: 78649390167     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.10.22     Document Type: Review
Times cited : (16)

References (200)
  • 1
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • Louis DN, Ohgaki H, Wiestler OD et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 114(2), 97 (2007).
    • (2007) Acta Neuropathol. , vol.114 , Issue.2 , pp. 97
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3
  • 3
    • 0037220864 scopus 로고    scopus 로고
    • Surgical management of brainstem hemangioblastomas in patients with von Hippel-Lindau disease
    • Weil RJ, Lonser RR, DeVroom HL, Wanebo JE, Oldfield EH. Surgical management of brainstem hemangioblastomas in patients with von Hippel-Lindau disease. J. Neurosurg. 98(1 Suppl.), 95-105 (2003). (Pubitemid 36050452)
    • (2003) Journal of Neurosurgery , vol.98 , Issue.1 SUPPL. , pp. 95-105
    • Weil, R.J.1    Lonser, R.R.2    DeVroom, H.L.3    Wanebo, J.E.4    Oldfield, E.H.5
  • 5
    • 70450248574 scopus 로고    scopus 로고
    • The Austrian brain tumour registry: A cooperative way to establish a population-based brain tumour registry
    • Wohrer A, Waldhor T, Heinzl H et al. The Austrian brain tumour registry: a cooperative way to establish a population-based brain tumour registry. J. Neurooncol. 95(3), 401-411 (2009).
    • (2009) J. Neurooncol. , vol.95 , Issue.3 , pp. 401-411
    • Wohrer, A.1    Waldhor, T.2    Heinzl, H.3
  • 6
    • 4344694453 scopus 로고    scopus 로고
    • Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System
    • DOI 10.1200/JCO.2004.12.149
    • Barnholtz-Sloan JS, Sloan AE, Davis FG, Vigneau FD, Lai P, Sawaya RE. Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J. Clin. Oncol. 22(14), 2865-2872 (2004). (Pubitemid 41079905)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.14 , pp. 2865-2872
    • Barnholtz-Sloan, J.S.1    Sloan, A.E.2    Davis, F.G.3    Vigneau, F.D.4    Lai, P.5    Sawaya, R.E.6
  • 8
    • 68949132486 scopus 로고    scopus 로고
    • Incidence of first primary central nervous system tumors in California, 2001-2005
    • Brown M, Schrot R, Bauer K, LeTendre D. Incidence of first primary central nervous system tumors in California, 2001-2005. J. Neurooncol. 94(2), 263-273 (2009).
    • (2009) J. Neurooncol. , vol.94 , Issue.2 , pp. 263-273
    • Brown, M.1    Schrot, R.2    Bauer, K.3    Letendre, D.4
  • 9
    • 73949093137 scopus 로고    scopus 로고
    • New challenges and opportunities in the management of brain metastases in patients with ErbB2-positive metastatic breast cancer
    • Melisko ME, Glantz M, Rugo HS. New challenges and opportunities in the management of brain metastases in patients with ErbB2-positive metastatic breast cancer. Nat. Clin. Pract. Oncol. 6(1), 25 (2009).
    • (2009) Nat. Clin. Pract. Oncol. , vol.6 , Issue.1 , pp. 25
    • Melisko, M.E.1    Glantz, M.2    Rugo, H.S.3
  • 10
    • 67649086209 scopus 로고    scopus 로고
    • Current management of metastatic brain disease
    • Ranjan T, Abrey LE. Current management of metastatic brain disease. Neurotherapeutics 6(3), 598 (2009).
    • (2009) Neurotherapeutics , vol.6 , Issue.3 , pp. 598
    • Ranjan, T.1    Abrey, L.E.2
  • 11
    • 9144232309 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma cell migration and invasion
    • DOI 10.1007/s11060-004-2751-6
    • Demuth T, Berens ME. Molecular mechanisms of glioma cell migration and invasion. J. Neurooncol. 70(2), 217-228 (2004). (Pubitemid 39545733)
    • (2004) Journal of Neuro-Oncology , vol.70 , Issue.2 , pp. 217-228
    • Demuth, T.1    Berens, M.E.2
  • 13
    • 75149112409 scopus 로고    scopus 로고
    • Future of convection-enhanced delivery in the treatment of brain tumors
    • Bidros DS, Liu JK, Vogelbaum MA. Future of convection-enhanced delivery in the treatment of brain tumors. Future Oncol. 6(1), 117-125 (2010).
    • (2010) Future Oncol. , vol.6 , Issue.1 , pp. 117-125
    • Bidros, D.S.1    Liu, J.K.2    Vogelbaum, M.A.3
  • 15
    • 70350151690 scopus 로고    scopus 로고
    • Convection-enhanced delivery for the treatment of brain tumors
    • Debinski W, Tatter SB. Convection-enhanced delivery for the treatment of brain tumors. Expert Rev. Neurother. 9(10), 1519-1527 (2009).
    • (2009) Expert Rev. Neurother. , vol.9 , Issue.10 , pp. 1519-1527
    • Debinski, W.1    Tatter, S.B.2
  • 17
    • 45849105207 scopus 로고    scopus 로고
    • Randomized Phase III controlled trials of therapy in malignant glioma: Where are we after 40 years?
    • DOI 10.1080/02688690701885603, PII 793686039
    • Anderson E, Grant R, Lewis SC, Whittle IR. Randomized Phase III controlled trials of therapy in malignant glioma: where are we after 40 years? British J. Neurosurg. 22(3), 339-349 (2008). (Pubitemid 351878617)
    • (2008) British Journal of Neurosurgery , vol.22 , Issue.3 , pp. 339-349
    • Anderson, E.1    Grant, R.2    Lewis, S.C.3    Whittle, I.R.4
  • 19
    • 44449135504 scopus 로고    scopus 로고
    • Adjuvant dibromodulcitol and BCNU chemotherapy in anaplastic astrocytoma: Results of a randomised European organisation for research and treatment of cancer Phase III study (EORTC study 26882)
    • Hildebrand J, Gorlia T, Kros JM et al. Adjuvant dibromodulcitol and BCNU chemotherapy in anaplastic astrocytoma: results of a randomised European organisation for research and treatment of cancer Phase III study (EORTC study 26882). Eur. J. Cancer 44(9), 1210-1216 (2008).
    • (2008) Eur. J. Cancer , vol.44 , Issue.9 , pp. 1210-1216
    • Hildebrand, J.1    Gorlia, T.2    Kros, J.M.3
  • 20
    • 71249117569 scopus 로고    scopus 로고
    • Primary postoperative chemotherapy without radiotherapy for treatment of brain tumours other than ependymoma in children under 3 years: Results of the first UKCCSG/SIOP CNS 9204 trial
    • Grundy RG, Wilne SH, Robinson KJ et al. Primary postoperative chemotherapy without radiotherapy for treatment of brain tumours other than ependymoma in children under 3 years: results of the first UKCCSG/SIOP CNS 9204 trial. Eur. J. Cancer 46(1), 120-133 (2010).
    • (2010) Eur. J. Cancer , vol.46 , Issue.1 , pp. 120-133
    • Grundy, R.G.1    Wilne, S.H.2    Robinson, K.J.3
  • 21
    • 77953611850 scopus 로고    scopus 로고
    • High-dose chemotherapy and autologous stem cell rescue for atypical teratoid/rhabdoid tumor of the central nervous system
    • Nicolaides T, Tihan T, Horn B, Biegel J, Prados M, Banerjee A. High-dose chemotherapy and autologous stem cell rescue for atypical teratoid/rhabdoid tumor of the central nervous system. J. Neurooncol. 98(1), 117-123 (2009).
    • (2009) J. Neurooncol. , vol.98 , Issue.1 , pp. 117-123
    • Nicolaides, T.1    Tihan, T.2    Horn, B.3    Biegel, J.4    Prados, M.5    Banerjee, A.6
  • 22
    • 75049083185 scopus 로고    scopus 로고
    • Effectiveness of temozolomide for primary glioblastoma multiforme in routine clinical practice
    • Van Genugten JAB, Leffers P, Baumert BG, Tjon-A-Fat H, Twijnstra A. Effectiveness of temozolomide for primary glioblastoma multiforme in routine clinical practice. J. Neurooncol. 96(2), 249-257 (2010).
    • (2010) J. Neurooncol. , vol.96 , Issue.2 , pp. 249-257
    • Van Genugten Jab1    Leffers, P.2    Baumert, B.G.3    Tjon-A-Fat, H.4    Twijnstra, A.5
  • 23
    • 77952294428 scopus 로고    scopus 로고
    • Small molecule kinase inhibitors in glioblastoma: A systematic review of clinical studies
    • De Witt Hamer PC. Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies. Neuro. Oncol. 12(3), 304-316 (2010).
    • (2010) Neuro. Oncol. , vol.12 , Issue.3 , pp. 304-316
    • De Witt Hamer, P.C.1
  • 24
    • 70449129458 scopus 로고    scopus 로고
    • Pediatric high-grade gliomas and diffuse intrinsic pontine gliomas
    • Fangusaro J. Pediatric high-grade gliomas and diffuse intrinsic pontine gliomas. J. Child Neurol. 24(11), 1409-1417 (2009).
    • (2009) J. Child Neurol. , vol.24 , Issue.11 , pp. 1409-1417
    • Fangusaro, J.1
  • 26
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised Phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised Phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 10(5), 459 (2009).
    • (2009) Lancet Oncol. , vol.10 , Issue.5 , pp. 459
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 27
    • 0017210792 scopus 로고
    • The application of brain capillary permeability coefficient measurements to pathological conditions and the selection of agents which cross the blood brain barrier
    • Levin VA, Landahl HD, Freeman Dove MA. The application of brain capillary permeability coefficient measurements to pathological conditions and the selection of agents which cross the blood brain barrier. J. Pharmacokinet. Biopharm. 4(6), 499 (1976).
    • (1976) J. Pharmacokinet. Biopharm. , vol.4 , Issue.6 , pp. 499
    • Levin, V.A.1    Landahl, H.D.2    Freeman Dove, M.A.3
  • 28
    • 60749134708 scopus 로고    scopus 로고
    • Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
    • Sarin H, Kanevsky A, Wu H et al. Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells. J. Transl. Med. 6(80) (2008).
    • (2008) J. Transl. Med. , vol.6 , pp. 80
    • Sarin, H.1    Kanevsky, A.2    Wu, H.3
  • 29
    • 70350502604 scopus 로고    scopus 로고
    • Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors
    • Sarin H. Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors. J. Transl. Med. 7, 77 (2009).
    • (2009) J. Transl. Med. , vol.7 , pp. 77
    • Sarin, H.1
  • 30
    • 0017643574 scopus 로고
    • Chemotherapy of brain tumors. The blood-brain barrier' is not a factor
    • Vick NA, Khandekar JD, Bigner DD. Chemotherapy of brain tumors. The blood-brain barrier' is not a factor. Arch. Neurol. 34(9), 523 (1977).
    • (1977) Arch. Neurol. , vol.34 , Issue.9 , pp. 523
    • Vick, N.A.1    Khandekar, J.D.2    Bigner, D.D.3
  • 31
    • 0021211007 scopus 로고
    • Tailor-making of protein drugs by polymer conjugation for tumor targeting: A brief review on smancs
    • Maeda H, Matsumoto T, Konno T, Iwai K, Ueda M. Tailor-making of protein drugs by polymer conjugation for tumor targeting: a brief review on SMANCS. J. Protein Chem. 3(2), 181-193 (1984). (Pubitemid 14046603)
    • (1984) Journal of Protein Chemistry , vol.3 , Issue.2 , pp. 181-193
    • Maeda, H.1    Matsumoto, T.2    Konno, T.3
  • 33
    • 0023481357 scopus 로고
    • Transport of molecules across tumor vasculature
    • Jain RK. Transport of molecules across tumor vasculature. Cancer Metastasis Rev. 6, 559-593 (1987).
    • (1987) Cancer Metastasis Rev. , vol.6 , pp. 559-593
    • Jain, R.K.1
  • 34
    • 0024584819 scopus 로고
    • Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection
    • Baxter LT, Jain RK. Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection. Microvasc. Res. 37(1), 77 (1989).
    • (1989) Microvasc. Res. , vol.37 , Issue.1 , pp. 77
    • Baxter, L.T.1    Jain, R.K.2
  • 35
    • 0015461491 scopus 로고
    • The role of the endothelial intercellular junctions in the functioning of the initial lymphatics
    • Casley-Smith JR. The role of the endothelial intercellular junctions in the functioning of the initial lymphatics. Angiologica 9(2), 106 (1972).
    • (1972) Angiologica , vol.9 , Issue.2 , pp. 106
    • Casley-Smith, J.R.1
  • 36
    • 0034662608 scopus 로고    scopus 로고
    • Absence of functional lymphatics within a murine sarcoma: A molecular and functional evaluation
    • Leu AJ, Berk DA, Lymboussaki A, Alitalo K, Jain RK. Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation. Cancer Res. 60(16), 4324-4327 (2000). (Pubitemid 32103603)
    • (2000) Cancer Research , vol.60 , Issue.16 , pp. 4324-4327
    • Leu, A.J.1    Berk, D.A.2    Lymboussaki, A.3    Alitalo, K.4    Jain, R.K.5
  • 37
    • 0024232289 scopus 로고
    • Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
    • Jain RK, Baxter LT. Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. Cancer Res. 48(24 Part 1), 7022-7032 (1988). (Pubitemid 19013976)
    • (1988) Cancer Research , vol.48 , Issue.24 , pp. 7022-7032
    • Jain, R.K.1    Baxter, L.T.2
  • 38
    • 2542628099 scopus 로고    scopus 로고
    • Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
    • DOI 10.1158/0008-5472.CAN-04-0074
    • Tong RT, Boucher Y, Kozin SV, Winkler F, Hicklin DJ, Jain RK. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res. 64(11), 3731-3736 (2004). (Pubitemid 38697278)
    • (2004) Cancer Research , vol.64 , Issue.11 , pp. 3731-3736
    • Tong, R.T.1    Boucher, Y.2    Kozin, S.V.3    Winkler, F.4    Hicklin, D.J.5    Jain, R.K.6
  • 39
    • 34047260282 scopus 로고    scopus 로고
    • Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: Insights from a mathematical model
    • DOI 10.1158/0008-5472.CAN-06-4102
    • Jain RK, Tong RT, Munn LL. Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res. 67(6), 2729-2735 (2007). (Pubitemid 46548961)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2729-2735
    • Jain, R.K.1    Tong, R.T.2    Munn, L.L.3
  • 40
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • DOI 10.1126/science.1104819
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307(5706), 58-62 (2005). (Pubitemid 40093472)
    • (2005) Science , vol.307 , Issue.5706 , pp. 58-62
    • Jain, R.K.1
  • 41
    • 0029949160 scopus 로고    scopus 로고
    • Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
    • DOI 10.1073/pnas.93.25.14765
    • Yuan F, Chen Y, Dellian M, Safabakhsh N, Ferrara N, Jain RK. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an antivascular endothelial growth factor/ vascular permeability factor antibody. Proc. Natl Acad. Sci. USA 93(25), 14765-14770 (1996). (Pubitemid 26419043)
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.25 , pp. 14765-14770
    • Yuan, F.1    Chen, Y.2    Dellian, M.3    Safabakhsh, N.4    Ferrara, N.5    Jain, R.K.6
  • 42
    • 30944446883 scopus 로고    scopus 로고
    • Lessons from phase III clinical trials on anti-VEGF therapy for cancer
    • DOI 10.1038/ncponc0403, PII N0403
    • Jain RK, Duda DG, Clark JW, Loeffler JS. Lessons from Phase III clinical trials on anti-VEGF therapy for cancer. Nat. Clin. Prac. Oncol. 3(1), 24-40 (2006). (Pubitemid 43108832)
    • (2006) Nature Clinical Practice Oncology , vol.3 , Issue.1 , pp. 24-40
    • Jain, R.K.1    Duda, D.G.2    Clark, J.W.3    Loeffler, J.S.4
  • 43
    • 75449088610 scopus 로고    scopus 로고
    • FDA drug approval summary: Bevacizumab (Avastin™) as treatment of recurrent glioblastoma multiforme
    • Cohen MH, Shen YL, Keegan P, Pazdur R. FDA drug approval summary: bevacizumab (Avastin™) as treatment of recurrent glioblastoma multiforme. Oncologist 14(11), 1131-1138 (2009).
    • (2009) Oncologist , vol.14 , Issue.11 , pp. 1131-1138
    • Cohen, M.H.1    Shen, Y.L.2    Keegan, P.3    Pazdur, R.4
  • 44
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • Friedman HS, Prados MD, Wen PY et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J. Clin. Oncol. 27(28), 4733-4740 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.28 , pp. 4733-4740
    • Friedman, H.S.1    Prados, M.D.2    Wen, P.Y.3
  • 45
    • 85157065984 scopus 로고    scopus 로고
    • Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma
    • DOI: 10.1093/annonc/mdp591(2010) Epub ahead of print
    • Verhoeff JJC, Lavini C, van Linde ME et al. Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma. Ann. Oncol. DOI: 10.1093/annonc/mdp591(2010) (Epub ahead of print).
    • Ann. Oncol.
    • Jjc, V.1    Lavini, C.2    Van Linde, M.E.3
  • 46
    • 0025316477 scopus 로고
    • Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat
    • Greig NH, Soncrant TT, Shetty HU, Momma S, Smith QR, Rapoport SI. Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat. Cancer Chemother. Pharmacol. 26(4), 263 (1990).
    • (1990) Cancer Chemother. Pharmacol. , vol.26 , Issue.4 , pp. 263
    • Greig, N.H.1    Soncrant, T.T.2    Shetty, H.U.3    Momma, S.4    Smith, Q.R.5    Rapoport, S.I.6
  • 47
    • 0029770135 scopus 로고    scopus 로고
    • MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors
    • Toth K, Vaughan M, Peress N, Slocum H, Rustum Y. MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors. Am. J. Pathol. 149(3), 853-858 (1996). (Pubitemid 26334169)
    • (1996) American Journal of Pathology , vol.149 , Issue.3 , pp. 853-858
    • Toth, K.1    Vaughan, M.M.2    Peress, N.S.3    Slocum, H.K.4    Rustum, Y.M.5
  • 48
    • 58949089716 scopus 로고    scopus 로고
    • A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients
    • Schaich M, Kestel L, Pfirrmann M et al. A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. Ann. Oncol. 20(1), 175-181 (2009).
    • (2009) Ann. Oncol. , vol.20 , Issue.1 , pp. 175-181
    • Schaich, M.1    Kestel, L.2    Pfirrmann, M.3
  • 49
    • 49649104978 scopus 로고    scopus 로고
    • Mechanisms of chemoresistance to alkylating agents in malignant glioma
    • Sarkaria JN, Kitange GJ, James CD et al. Mechanisms of chemoresistance to alkylating agents in malignant glioma. Clin. Cancer Res. 14(10), 2900-2908 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.10 , pp. 2900-2908
    • Sarkaria, J.N.1    Kitange, G.J.2    James, C.D.3
  • 52
    • 66949164471 scopus 로고    scopus 로고
    • Metabolically stable bradykinin B2 receptor agonists enhance transvascular drug delivery into malignant brain tumors by increasing drug half-life
    • Sarin H, Kanevsky AS, Fung SH et al. Metabolically stable bradykinin B2 receptor agonists enhance transvascular drug delivery into malignant brain tumors by increasing drug half-life. J. Transl. Med. 7, 33 (2009).
    • (2009) J. Transl. Med. , vol.7 , pp. 33
    • Sarin, H.1    Kanevsky, A.S.2    Fung, S.H.3
  • 53
    • 38949167506 scopus 로고    scopus 로고
    • Clinical pharmacology of cancer therapies in older adults
    • DOI 10.1038/sj.bjc.6604201, PII 6604201
    • Hurria A, Lichtman SM. Clinical pharmacology of cancer therapies in older adults. Br. J. Cancer 98(3), 517-522 (2008). (Pubitemid 351214530)
    • (2008) British Journal of Cancer , vol.98 , Issue.3 , pp. 517-522
    • Hurria, A.1    Lichtman, S.M.2
  • 54
    • 0033638464 scopus 로고    scopus 로고
    • Population pharmacokinetics of temozolomide in cancer patients
    • Jen JF, Cutler DL, Pai SM et al. Population pharmacokinetics of temozolomide in cancer patients. Pharm. Res. 17(10), 1284-1289 (2000).
    • (2000) Pharm. Res. , vol.17 , Issue.10 , pp. 1284-1289
    • Jen, J.F.1    Cutler, D.L.2    Pai, S.M.3
  • 55
    • 0018254720 scopus 로고
    • Relationship of 1,3-bis(2-chloroethyl)-1- nitrosourea (BCNU) and 1-(2-chloroethyl)- 3-cyclohexyl-1-nitrosourea (CCNU) pharmacokinetics of uptake, distribution, and tissue/plasma partitioning in rat organs and intracerebral tumors
    • Levin VA, Kabra PA, Freeman-Dove MA. Relationship of 1,3-bis(2- chloroethyl)-1- nitrosourea (BCNU) and 1-(2-chloroethyl)- 3-cyclohexyl-1- nitrosourea (CCNU) pharmacokinetics of uptake, distribution, and tissue/plasma partitioning in rat organs and intracerebral tumors. Cancer Chemother. Pharmacol. 1(4), 233 (1978).
    • (1978) Cancer Chemother. Pharmacol. , vol.1 , Issue.4 , pp. 233
    • Levin, V.A.1    Kabra, P.A.2    Freeman Dove, M.A.3
  • 56
    • 0016310005 scopus 로고
    • Effectiveness of the nitrosoureas as a function of their lipid solubility in the chemotherapy of experimental rat brain tumors
    • Levin VA, Kabra P. Effectiveness of the nitrosoureas as a function of their lipid solubility in the chemotherapy of experimental rat brain tumors. Cancer Chemother. Rep. 58(6), 787 (1974).
    • (1974) Cancer Chemother. Rep. , vol.58 , Issue.6 , pp. 787
    • Levin, V.A.1    Kabra, P.2
  • 57
    • 85157172970 scopus 로고    scopus 로고
    • Effective transvascular delivery of chemotherapy into cancer cells with imageable nanoparticles in the 7-10 nanometer size range
    • Slevin M (Ed), eBentham Books In Press
    • Sarin H. Effective transvascular delivery of chemotherapy into cancer cells with imageable nanoparticles in the 7-10 nanometer size range. In:Current Advances in the Medical Application of Nanotechnology. Slevin M (Ed), eBentham Books (2010) (In Press).
    • Current Advances in the Medical Application of Nanotechnology. , pp. 2010
    • Sarin, H.1
  • 58
    • 67650727594 scopus 로고    scopus 로고
    • Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors
    • DOI: 10.1186/1479-5876-7-51
    • Sarin H, Kanevsky A, Wu H et al. Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors. J. Transl. Med. 7(51) DOI: 10.1186/1479-5876-7-51 (2009).
    • (2009) J. Transl. Med. , vol.7 , pp. 51
    • Sarin, H.1    Kanevsky, A.2    Wu, H.3
  • 59
    • 0023157363 scopus 로고
    • Angiogenic factors
    • Folkman J, Klagsbrun M. Angiogenic factors. Science 235(4787), 442-447 (1987). (Pubitemid 17009577)
    • (1987) Science , vol.235 , Issue.4787 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 60
    • 0031045279 scopus 로고    scopus 로고
    • Neovasculature induced by vascular endothelial growth factor is fenestrated
    • Roberts WG, Palade GE. Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res. 57(4), 765-772 (1997). (Pubitemid 27085664)
    • (1997) Cancer Research , vol.57 , Issue.4 , pp. 765-772
    • Roberts, W.G.1    Palade, G.E.2
  • 62
    • 33744896240 scopus 로고
    • The excretion of protein by the mammalian kidney
    • Bayliss LE, Kerridge PMT, Russell DS. The excretion of protein by the mammalian kidney. J. Physiol. 77(4), 386-398 (1933).
    • (1933) J. Physiol. , vol.77 , Issue.4 , pp. 386-398
    • Bayliss, L.E.1    Pmt, K.2    Russell, D.S.3
  • 63
    • 0024390069 scopus 로고
    • Ultracytochemical characterization of anionic sites in the wall of brain capillaries
    • DOI 10.1007/BF01190839
    • Vorbrodt AW. Ultracytochemical characterization of anionic sites in the wall of brain capillaries. J. Neurocytol. 18(3), 359-368 (1989). (Pubitemid 19147403)
    • (1989) Journal of Neurocytology , vol.18 , Issue.3 , pp. 359-368
    • Vorbrodt, A.W.1
  • 64
    • 0022644358 scopus 로고
    • Anionic sites on the luminal surface of fenestrated and continuous capillaries of the CNS
    • DOI 10.1016/0006-8993(86)91011-5
    • Schmidley JW, Wissig SL. Anionic sites on the luminal surface of fenestrated and continuous capillaries of the CNS. Brain Res. 363(2), 265-271 (1986). (Pubitemid 16146274)
    • (1986) Brain Research , vol.363 , Issue.2 , pp. 265-271
    • Schmidley, J.W.1    Wissig, S.L.2
  • 65
    • 0017689969 scopus 로고
    • Morphology of blood-brain interfaces
    • DOI 10.1016/0014-4835(77)90239-1
    • Brightman MW. Morphology of blood-brain interfaces. Exp. Eye Res. 25(Suppl), 1-25 (1977). (Pubitemid 8205025)
    • (1977) Experimental Eye Research , vol.25 , Issue.SUPPL. , pp. 1-25
    • Brightman, M.W.1
  • 66
    • 0014481056 scopus 로고
    • Junctions between intimately apposed cell membranes in the vertebrate brain
    • Brightman MW, Reese TS. Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol. 40(3), 648-677 (1969).
    • (1969) J. Cell Biol. , vol.40 , Issue.3 , pp. 648-677
    • Brightman, M.W.1    Reese, T.S.2
  • 67
    • 0015400075 scopus 로고
    • Microvascular abnormalities in virally-induced canine brain tumors. Structural bases for altered blood-brain barrier function
    • Vick NA, Bigner DD. Microvascular abnormalities in virally-induced canine brain tumors. Structural bases for altered blood-brain barrier function. J. Neurol. Sci. 17, 29-39 (1972).
    • (1972) J. Neurol. Sci. , vol.17 , pp. 29-39
    • Vick, N.A.1    Bigner, D.D.2
  • 68
    • 77956162919 scopus 로고    scopus 로고
    • Physiologic upper limits of pore size of different blood capillary types and another perspective on the dual pore theory of microvascular permeability
    • In Press
    • Sarin H. Physiologic upper limits of pore size of different blood capillary types and another perspective on the dual pore theory of microvascular permeability. J. Angiogenes. Res. (2010) (In Press).
    • J. Angiogenes. Res. , pp. 2010
    • Sarin, H.1
  • 70
    • 0029797605 scopus 로고    scopus 로고
    • Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries
    • Vink H, Duling BR. Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries. Circ. Res. 79(3), 581-589 (1996). (Pubitemid 26276918)
    • (1996) Circulation Research , vol.79 , Issue.3 , pp. 581-589
    • Vink, H.1    Duling, B.R.2
  • 71
    • 0035782689 scopus 로고    scopus 로고
    • Quasi-periodic substructure in the microvessel endothelial glycocalyx: A possible explanation for molecular filtering?
    • Squire JM, Chew M, Nneji G, Neal C, Barry J, Michel C. Quasi-periodic substructure in the microvessel endothelial glycocalyx: a possible explanation for molecular filtering? J. Struct. Biol. 136(3), 239-255 (2001).
    • (2001) J. Struct. Biol. , vol.136 , Issue.3 , pp. 239-255
    • Squire, J.M.1    Chew, M.2    Nneji, G.3    Neal, C.4    Barry, J.5    Michel, C.6
  • 72
    • 0034662609 scopus 로고    scopus 로고
    • Hyperthermia enables tumor-specific nanoparticle delivery: Effect of particle size
    • Kong G, Braun RD, Dewhirst MW. Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res. 60(16), 4440-4445 (2000). (Pubitemid 32103623)
    • (2000) Cancer Research , vol.60 , Issue.16 , pp. 4440-4445
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 73
    • 0026335518 scopus 로고
    • Pharmacokinetic and imaging studies in patients receiving a formulation of liposome-associated adriamycin
    • Gabizon A, Chisin R, Amselem S et al. Pharmacokinetic and imaging studies in patients receiving a formulation of liposome-associated adriamycin. Br. J. Cancer 64(6), 1125-1132 (1991).
    • (1991) Br. J. Cancer , vol.64 , Issue.6 , pp. 1125-1132
    • Gabizon, A.1    Chisin, R.2    Amselem, S.3
  • 76
    • 0013934801 scopus 로고
    • Filtration and reflection coefficients of the rabbit blood-brain barrier
    • Fenstermacher JD, Johnson JA. Filtration and reflection coefficients of the rabbit blood-brain barrier. Am. J. Physiol. 211(2), 341-346 (1966).
    • (1966) Am. J. Physiol. , vol.211 , Issue.2 , pp. 341-346
    • Fenstermacher, J.D.1    Johnson, J.A.2
  • 77
    • 0015955617 scopus 로고
    • The permeability to small ions of tight junctions between cerebral endothelial cells
    • Sorensen SC. The permeability to small ions of tight junctions between cerebral endothelial cells. Brain Res. 70(1), 174-178 (1974).
    • (1974) Brain Res. , vol.70 , Issue.1 , pp. 174-178
    • Sorensen, S.C.1
  • 79
    • 27644512708 scopus 로고    scopus 로고
    • Quantitative measurement of leakage volume and permeability in gliomas, meningiomas and brain metastases with dynamic contrast-enhanced MRI
    • Ludemann L, Grieger W, Wurm R, Wust P, Zimmer C. Quantitative measurement of leakage volume and permeability in gliomas, meningiomas and brain metastases with dynamic contrast-enhanced MRI. Magn. Reson. Imaging 23(8), 833 (2005).
    • (2005) Magn. Reson. Imaging , vol.23 , Issue.8 , pp. 833
    • Ludemann, L.1    Grieger, W.2    Wurm, R.3    Wust, P.4    Zimmer, C.5
  • 80
    • 0036179912 scopus 로고    scopus 로고
    • Comparison of permeability in high-grade and low-grade brain tumors using dynamic susceptibility contrast MR imaging
    • Provenzale JM, Wang GR, Brenner T, Petrella JR, Sorensen AG. Comparison of permeability in high-grade and low-grade brain tumors using dynamic susceptibility contrast MR imaging. Am. J. Roentgenol. 178(3), 711 (2002).
    • (2002) Am. J. Roentgenol. , vol.178 , Issue.3 , pp. 711
    • Provenzale, J.M.1    Wang, G.R.2    Brenner, T.3    Petrella, J.R.4    Sorensen, A.G.5
  • 81
    • 0024373738 scopus 로고
    • Structure, composition, and assembly of basement membrane
    • Leblond CP, Inoue S. Structure, composition, and assembly of basement membrane. Am. J. Anat. 185(4), 367-390 (1989). (Pubitemid 19213501)
    • (1989) American Journal of Anatomy , vol.185 , Issue.4 , pp. 367-390
    • Leblond, C.P.1    Inoue, S.2
  • 82
    • 0020535249 scopus 로고
    • Anionic sites in basement membranes. Differences in their electrostatic properties in continuous and fenestrated capillaries
    • Charonis AS, Wissig SL. Anionic sites in basement membranes. Differences in their electrostatic properties in continuous and fenestrated capillaries. Microvasc. Res. 25(3), 265-285 (1983). (Pubitemid 13120308)
    • (1983) Microvascular Research , vol.25 , Issue.3 , pp. 265-285
    • Charonis, A.S.1    Wissig, S.L.2
  • 83
    • 0030055404 scopus 로고    scopus 로고
    • An immunohistochemical study of tumour vessels in metastatic liver cancers and the surrounding liver tissue
    • Terayama N, Terada T, Nakanuma Y. An immunohistochemical study of tumour vessels in metastatic liver cancers and the surrounding liver tissue. Histopathology 29(1), 37-43 (1996). (Pubitemid 26232520)
    • (1996) Histopathology , vol.29 , Issue.1 , pp. 37-43
    • Terayama, N.1    Terada, T.2    Nakanuma, Y.3
  • 85
    • 0142151097 scopus 로고    scopus 로고
    • Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors
    • Baluk P, Morikawa S, Haskell A, Mancuso M, McDonald DM. Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 163(5), 1801-1815 (2003). (Pubitemid 37310012)
    • (2003) American Journal of Pathology , vol.163 , Issue.5 , pp. 1801-1815
    • Baluk, P.1    Morikawa, S.2    Haskell, A.3    Mancuso, M.4    McDonald, D.M.5
  • 86
    • 0018286491 scopus 로고
    • Ultrastructural observations on the capillaries of human thyroid tumours
    • DOI 10.1002/path.1711280202
    • Ludatscher RM, Gellei B, Barzilai D. Ultrastructural observations on the capillaries of human thyroid tumours. J.Pathol. 128(2), 57-62 (1979). (Pubitemid 9250782)
    • (1979) Journal of Pathology , vol.128 , Issue.2 , pp. 57-62
    • Ludatscher, R.M.1    Gellei, B.2    Barzilai, D.3
  • 88
    • 0024444606 scopus 로고
    • Ultrastructure of capillary walls in human brain tumors
    • Shibata S. Ultrastructure of capillary walls in human brain tumors. Acta Neuropathol. 78(6), 561-571 (1989). (Pubitemid 19251310)
    • (1989) Acta Neuropathologica , vol.78 , Issue.6 , pp. 561-571
    • Shibata, S.1
  • 89
    • 0017137661 scopus 로고
    • Single agent chemotherapy of brain tumors. A five year review
    • Wilson CB, Gutin P, Boldrey EB. Single agent chemotherapy of brain tumors. A five year review. Arch. Neurol. 33(1), 739-744 (1976).
    • (1976) Arch. Neurol. , vol.33 , Issue.1 , pp. 739-744
    • Wilson, C.B.1    Gutin, P.2    Boldrey, E.B.3
  • 91
    • 0015530009 scopus 로고
    • The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine
    • Fewer D, Wilson CB, Boldrey EB, Enot KJ, Powell MR. The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine. JAMA 222(5), 549-552 (1972).
    • (1972) JAMA , vol.222 , Issue.5 , pp. 549-552
    • Fewer, D.1    Wilson, C.B.2    Boldrey, E.B.3    Enot, K.J.4    Powell, M.R.5
  • 92
    • 62349087854 scopus 로고    scopus 로고
    • Recent approaches to improve the anti-tumor efficacy of temozolomide
    • Tentori L, Graziani G. Recent approaches to improve the anti-tumor efficacy of temozolomide. Curr. Med. Chem. 16(2), 245-257 (2009).
    • (2009) Curr. Med. Chem. , vol.16 , Issue.2 , pp. 245-257
    • Tentori, L.1    Graziani, G.2
  • 93
    • 43749091506 scopus 로고    scopus 로고
    • Showering c-MET-dependent cancers with drugs
    • DOI 10.1016/j.gde.2008.02.001, PII S0959437X08000269
    • Knudsen BS, Vande Woude G. Showering c-MET-dependent cancers with drugs. Curr. Opin. Genet. Dev. 18(1), 87-96 (2008). (Pubitemid 351694452)
    • (2008) Current Opinion in Genetics and Development , vol.18 , Issue.1 , pp. 87-96
    • Knudsen, B.S.1    Vande Woude, G.2
  • 94
    • 61349165472 scopus 로고    scopus 로고
    • Pharmacotherapy for adults with tumors of the central nervous system
    • Schor NF. Pharmacotherapy for adults with tumors of the central nervous system. Pharmacol. Ther. 121, 253-264 (2009).
    • (2009) Pharmacol. Ther. , vol.121 , pp. 253-264
    • Schor, N.F.1
  • 95
    • 0019124032 scopus 로고
    • Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
    • DOI 10.1021/jm00180a022
    • Levin VA. Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J. Med. Chem. 23(6), 682-684 (1980). (Pubitemid 11237830)
    • (1980) Journal of Medicinal Chemistry , vol.23 , Issue.6 , pp. 682-684
    • Levin, V.A.1
  • 96
    • 33749236438 scopus 로고    scopus 로고
    • Skin delivery potency and anti-tumor activities of temozolomide ester prodrugs
    • Panassaya S, Guocheng W, Barbara RC, Weidong W, Yongfeng W. Skin delivery potency and anti-tumor activities of temozolomide ester prodrugs. Cancer Lett. 244(1), 42-52 (2006).
    • (2006) Cancer Lett. , vol.244 , Issue.1 , pp. 42-52
    • Panassaya, S.1    Guocheng, W.2    Barbara, R.C.3    Weidong, W.4    Yongfeng, W.5
  • 97
    • 77049129026 scopus 로고
    • Passage of molecules through capillary walls
    • Pappenheimer JR. Passage of molecules through capillary walls. Physiol. Rev. 33(3), 387-423 (1953).
    • (1953) Physiol. Rev. , vol.33 , Issue.3 , pp. 387-423
    • Pappenheimer, J.R.1
  • 98
    • 0030993717 scopus 로고    scopus 로고
    • Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials
    • DOI 10.1016/S0305-7372(97)90019-0
    • Newlands ES, Stevens MF, Wedge SR, Wheelhouse RT, Brock C. Temozolomide: a review of its discovery, chemical properties, preclinical development and clinical trials. Cancer Treat. Rev. 23(1), 35-61 (1997). (Pubitemid 27273454)
    • (1997) Cancer Treatment Reviews , vol.23 , Issue.1 , pp. 35-61
    • Newlands, E.S.1    Stevens, M.F.G.2    Wedge, S.R.3    Wheelhouse, R.T.4    Brock, C.5
  • 99
    • 0023682240 scopus 로고
    • Clinical pharmacokinetics of doxorubicin
    • Speth PAJ, Van Hoesel QGCM, Haanen C. Clinical pharmacokinetics of doxorubicin. Clin. Pharmacokinet. 15(1), 15-31 (1988).
    • (1988) Clin. Pharmacokinet. , vol.15 , Issue.1 , pp. 15-31
    • Paj, S.1    Van Hoesel Qgcm2    Haanen, C.3
  • 100
    • 0014139605 scopus 로고
    • The ultrastructural basis of capillary permeability studied with peroxidase as a tracer
    • Karnovsky MJ. The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. J. Cell Biol. 35(1), 213-236 (1967).
    • (1967) J. Cell Biol. , vol.35 , Issue.1 , pp. 213-236
    • Karnovsky, M.J.1
  • 101
    • 42149117803 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system
    • DOI 10.1002/cncr.23362
    • Gill P, Litzow M, Buckner J et al. High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system. Cancer 112(8), 1805-1811 (2008). (Pubitemid 351536841)
    • (2008) Cancer , vol.112 , Issue.8 , pp. 1805-1811
    • Gill, P.1    Litzow, M.2    Buckner, J.3    Arndt, C.4    Moynihan, T.5    Christianson, T.6    Ansell, S.7    Galanis, E.8
  • 102
    • 0036171122 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous stem cell rescue for brain tumors
    • DOI 10.1016/S1040-8428(01)00156-1, PII S1040842801001561
    • Dunkel IJ, Finlay JL. High-dose chemotherapy with autologous stem cell rescue for brain tumors. Crit. Rev. Oncol. Hematol. 41(2), 197-204 (2002). (Pubitemid 34150130)
    • (2002) Critical Reviews in Oncology/Hematology , vol.41 , Issue.2 , pp. 197-204
    • Dunkel, I.J.1    Finlay, J.L.2
  • 103
    • 77952198779 scopus 로고    scopus 로고
    • High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma
    • Dunkel IJ, Gardner SL, Garvin JH Jr, Goldman S, Shibata S. High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma. J. Clin. Oncol. 12(3), 297-303 (2010).
    • (2010) J. Clin. Oncol. , vol.12 , Issue.3 , pp. 297-303
    • Dunkel, I.J.1    Gardner, S.L.2    Garvin Jr., J.H.3    Goldman, S.4    Shibata, S.5
  • 104
    • 68949085460 scopus 로고    scopus 로고
    • Randomized Phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma
    • Clarke JL, Iwamoto FM, Sul J et al. Randomized Phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma. J. Clin. Oncol. 27(23), 3861-3867 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.23 , pp. 3861-3867
    • Clarke, J.L.1    Iwamoto, F.M.2    Sul, J.3
  • 105
    • 29844433011 scopus 로고    scopus 로고
    • Intra-arterial chemotherapy of primary brain tumors
    • Newton HB. Intra-arterial chemotherapy of primary brain tumors. Curr. Treat. Options Oncol. 6(6), 519-530 (2005). (Pubitemid 43033781)
    • (2005) Current Treatment Options in Oncology , vol.6 , Issue.6 , pp. 519-530
    • Newton, H.B.1
  • 106
    • 4344691713 scopus 로고    scopus 로고
    • Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors
    • Warren K, Gervais A, Aikin A, Egorin M, Balis FM. Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors. Cancer Chemother. Pharmacol. 54(3), 206-212 (2004). (Pubitemid 39141736)
    • (2004) Cancer Chemotherapy and Pharmacology , vol.54 , Issue.3 , pp. 206-212
    • Warren, K.1    Gervais, A.2    Aikin, A.3    Egorin, M.4    Balis, F.M.5
  • 107
    • 0034061487 scopus 로고    scopus 로고
    • Pharmacokinetics of carboplatin administered in combination with the bradykinin agonist Cereport (RMP-7) for the treatment of brain tumours
    • Thomas HD, Lind MJ, Ford J, Bleehen N, Calvert AH, Boddy AV. Pharmacokinetics of carboplatin administered in combination with the bradykinin agonist Cereport (RMP-7) for the treatment of brain tumours. Cancer Chemother. Pharmacol. 45(4), 284 (2000).
    • (2000) Cancer Chemother. Pharmacol. , vol.45 , Issue.4 , pp. 284
    • Thomas, H.D.1    Lind, M.J.2    Ford, J.3    Bleehen, N.4    Calvert, A.H.5    Boddy, A.V.6
  • 109
    • 0033959628 scopus 로고    scopus 로고
    • Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model
    • Moore A, Marecos E, Bogdanov A, Weissleder R. Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model. Radiology 214, 568-574 (2000). (Pubitemid 30077721)
    • (2000) Radiology , vol.214 , Issue.2 , pp. 568-574
    • Moore, A.1    Marecos, E.2    Bogdanov Jr., A.3    Weissleder, R.4
  • 110
    • 0033974507 scopus 로고    scopus 로고
    • Osmotic opening of the blood-brain barrier: Principles, mechanism, and therapeutic applications
    • Rapoport SI. Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications. Cell. Mol. Neurobiol. 20(2), 217 (2000).
    • (2000) Cell. Mol. Neurobiol. , vol.20 , Issue.2 , pp. 217
    • Rapoport, S.I.1
  • 111
    • 0035300546 scopus 로고    scopus 로고
    • Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature
    • Kong G, Braun RD, Dewhirst MW. Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature. Cancer Res. 61(7), 3027-3032 (2001). (Pubitemid 32691950)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 3027-3032
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 112
    • 0013934801 scopus 로고
    • Filtration and reflection coefficients of the rabbit blood-brain barrier
    • Fenstermacher JD, Johnson JA. Filtration and reflection coefficients of the rabbit blood-brain barrier. Am. J. Physiol. 211(2), 341-346 (1966).
    • (1966) Am. J. Physiol. , vol.211 , Issue.2 , pp. 341-346
    • Fenstermacher, J.D.1    Johnson, J.A.2
  • 113
    • 0015955617 scopus 로고
    • The permeability to small ions of tight junctions between cerebral endothelial cells
    • Sorensen SC. The permeability to small ions of tight junctions between cerebral endothelial cells. Brain Res. 70(1), 174-178 (1974).
    • (1974) Brain Res. , vol.70 , Issue.1 , pp. 174-178
    • Sorensen, S.C.1
  • 115
    • 27644512708 scopus 로고    scopus 로고
    • Quantitative measurement of leakage volume and permeability in gliomas, meningiomas and brain metastases with dynamic contrast-enhanced MRI
    • Ludemann L, Grieger W, Wurm R, Wust P, Zimmer C. Quantitative measurement of leakage volume and permeability in gliomas, meningiomas and brain metastases with dynamic contrast-enhanced MRI. Magn. Reson. Imaging 23(8), 833 (2005).
    • (2005) Magn. Reson. Imaging , vol.23 , Issue.8 , pp. 833
    • Ludemann, L.1    Grieger, W.2    Wurm, R.3    Wust, P.4    Zimmer, C.5
  • 116
    • 0036179912 scopus 로고    scopus 로고
    • Comparison of permeability in high-grade and low-grade brain tumors using dynamic susceptibility contrast MR imaging
    • Provenzale JM, Wang GR, Brenner T, Petrella JR, Sorensen AG. Comparison of permeability in high-grade and low-grade brain tumors using dynamic susceptibility contrast MR imaging. Am. J. Roentgenol. 178(3), 711 (2002).
    • (2002) Am. J. Roentgenol. , vol.178 , Issue.3 , pp. 711
    • Provenzale, J.M.1    Wang, G.R.2    Brenner, T.3    Petrella, J.R.4    Sorensen, A.G.5
  • 117
    • 0024373738 scopus 로고
    • Structure, composition, and assembly of basement membrane
    • Leblond CP, Inoue S. Structure, composition, and assembly of basement membrane. Am. J. Anat. 185(4), 367-390 (1989). (Pubitemid 19213501)
    • (1989) American Journal of Anatomy , vol.185 , Issue.4 , pp. 367-390
    • Leblond, C.P.1    Inoue, S.2
  • 118
    • 0020535249 scopus 로고
    • Anionic sites in basement membranes. Differences in their electrostatic properties in continuous and fenestrated capillaries
    • Charonis AS, Wissig SL. Anionic sites in basement membranes. Differences in their electrostatic properties in continuous and fenestrated capillaries. Microvasc. Res. 25(3), 265-285 (1983). (Pubitemid 13120308)
    • (1983) Microvascular Research , vol.25 , Issue.3 , pp. 265-285
    • Charonis, A.S.1    Wissig, S.L.2
  • 119
    • 0030055404 scopus 로고    scopus 로고
    • An immunohistochemical study of tumour vessels in metastatic liver cancers and the surrounding liver tissue
    • Terayama N, Terada T, Nakanuma Y. An immunohistochemical study of tumour vessels in metastatic liver cancers and the surrounding liver tissue. Histopathology 29(1), 37-43 (1996). (Pubitemid 26232520)
    • (1996) Histopathology , vol.29 , Issue.1 , pp. 37-43
    • Terayama, N.1    Terada, T.2    Nakanuma, Y.3
  • 121
    • 0142151097 scopus 로고    scopus 로고
    • Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors
    • Baluk P, Morikawa S, Haskell A, Mancuso M, McDonald DM. Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 163(5), 1801-1815 (2003). (Pubitemid 37310012)
    • (2003) American Journal of Pathology , vol.163 , Issue.5 , pp. 1801-1815
    • Baluk, P.1    Morikawa, S.2    Haskell, A.3    Mancuso, M.4    McDonald, D.M.5
  • 122
    • 0018286491 scopus 로고
    • Ultrastructural observations on the capillaries of human thyroid tumours
    • DOI 10.1002/path.1711280202
    • Ludatscher RM, Gellei B, Barzilai D. Ultrastructural observations on the capillaries of human thyroid tumours. J.Pathol. 128(2), 57-62 (1979). (Pubitemid 9250782)
    • (1979) Journal of Pathology , vol.128 , Issue.2 , pp. 57-62
    • Ludatscher, R.M.1    Gellei, B.2    Barzilai, D.3
  • 124
    • 0024444606 scopus 로고
    • Ultrastructure of capillary walls in human brain tumors
    • Shibata S. Ultrastructure of capillary walls in human brain tumors. Acta Neuropathol. 78(6), 561-571 (1989). (Pubitemid 19251310)
    • (1989) Acta Neuropathologica , vol.78 , Issue.6 , pp. 561-571
    • Shibata, S.1
  • 125
    • 0017137661 scopus 로고
    • Single agent chemotherapy of brain tumors. A five year review
    • Wilson CB, Gutin P, Boldrey EB. Single agent chemotherapy of brain tumors. A five year review. Arch. Neurol. 33(1), 739-744 (1976).
    • (1976) Arch. Neurol. , vol.33 , Issue.1 , pp. 739-744
    • Wilson, C.B.1    Gutin, P.2    Boldrey, E.B.3
  • 127
    • 0015530009 scopus 로고
    • The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine
    • Fewer D, Wilson CB, Boldrey EB, Enot KJ, Powell MR. The chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristine. JAMA 222(5), 549-552 (1972).
    • (1972) JAMA , vol.222 , Issue.5 , pp. 549-552
    • Fewer, D.1    Wilson, C.B.2    Boldrey, E.B.3    Enot, K.J.4    Powell, M.R.5
  • 128
    • 62349087854 scopus 로고    scopus 로고
    • Recent approaches to improve the anti-tumor efficacy of temozolomide
    • Tentori L, Graziani G. Recent approaches to improve the anti-tumor efficacy of temozolomide. Curr. Med. Chem. 16(2), 245-257 (2009).
    • (2009) Curr. Med. Chem. , vol.16 , Issue.2 , pp. 245-257
    • Tentori, L.1    Graziani, G.2
  • 129
    • 43749091506 scopus 로고    scopus 로고
    • Showering c-MET-dependent cancers with drugs
    • DOI 10.1016/j.gde.2008.02.001, PII S0959437X08000269
    • Knudsen BS, Vande Woude G. Showering c-MET-dependent cancers with drugs. Curr. Opin. Genet. Dev. 18(1), 87-96 (2008). (Pubitemid 351694452)
    • (2008) Current Opinion in Genetics and Development , vol.18 , Issue.1 , pp. 87-96
    • Knudsen, B.S.1    Vande Woude, G.2
  • 130
    • 61349165472 scopus 로고    scopus 로고
    • Pharmacotherapy for adults with tumors of the central nervous system
    • Schor NF. Pharmacotherapy for adults with tumors of the central nervous system. Pharmacol. Ther. 121, 253-264 (2009).
    • (2009) Pharmacol. Ther. , vol.121 , pp. 253-264
    • Schor, N.F.1
  • 131
    • 0019124032 scopus 로고
    • Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
    • DOI 10.1021/jm00180a022
    • Levin VA. Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J. Med. Chem. 23(6), 682-684 (1980). (Pubitemid 11237830)
    • (1980) Journal of Medicinal Chemistry , vol.23 , Issue.6 , pp. 682-684
    • Levin, V.A.1
  • 132
    • 33749236438 scopus 로고    scopus 로고
    • Skin delivery potency and anti-tumor activities of temozolomide ester prodrugs
    • Panassaya S, Guocheng W, Barbara RC, Weidong W, Yongfeng W. Skin delivery potency and anti-tumor activities of temozolomide ester prodrugs. Cancer Lett. 244(1), 42-52 (2006).
    • (2006) Cancer Lett. , vol.244 , Issue.1 , pp. 42-52
    • Panassaya, S.1    Guocheng, W.2    Barbara, R.C.3    Weidong, W.4    Yongfeng, W.5
  • 133
    • 77049129026 scopus 로고
    • Passage of molecules through capillary walls
    • Pappenheimer JR. Passage of molecules through capillary walls. Physiol. Rev. 33(3), 387-423 (1953).
    • (1953) Physiol. Rev. , vol.33 , Issue.3 , pp. 387-423
    • Pappenheimer, J.R.1
  • 134
    • 0030993717 scopus 로고    scopus 로고
    • Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials
    • DOI 10.1016/S0305-7372(97)90019-0
    • Newlands ES, Stevens MF, Wedge SR, Wheelhouse RT, Brock C. Temozolomide: a review of its discovery, chemical properties, preclinical development and clinical trials. Cancer Treat. Rev. 23(1), 35-61 (1997). (Pubitemid 27273454)
    • (1997) Cancer Treatment Reviews , vol.23 , Issue.1 , pp. 35-61
    • Newlands, E.S.1    Stevens, M.F.G.2    Wedge, S.R.3    Wheelhouse, R.T.4    Brock, C.5
  • 135
    • 0023682240 scopus 로고
    • Clinical pharmacokinetics of doxorubicin
    • Speth PAJ, Van Hoesel QGCM, Haanen C. Clinical pharmacokinetics of doxorubicin. Clin. Pharmacokinet. 15(1), 15-31 (1988).
    • (1988) Clin. Pharmacokinet. , vol.15 , Issue.1 , pp. 15-31
    • Paj, S.1    Van Hoesel Qgcm2    Haanen, C.3
  • 136
    • 0014139605 scopus 로고
    • The ultrastructural basis of capillary permeability studied with peroxidase as a tracer
    • Karnovsky MJ. The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. J. Cell Biol. 35(1), 213-236 (1967).
    • (1967) J. Cell Biol. , vol.35 , Issue.1 , pp. 213-236
    • Karnovsky, M.J.1
  • 137
    • 42149117803 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system
    • DOI 10.1002/cncr.23362
    • Gill P, Litzow M, Buckner J et al. High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system. Cancer 112(8), 1805-1811 (2008). (Pubitemid 351536841)
    • (2008) Cancer , vol.112 , Issue.8 , pp. 1805-1811
    • Gill, P.1    Litzow, M.2    Buckner, J.3    Arndt, C.4    Moynihan, T.5    Christianson, T.6    Ansell, S.7    Galanis, E.8
  • 138
    • 0036171122 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous stem cell rescue for brain tumors
    • DOI 10.1016/S1040-8428(01)00156-1, PII S1040842801001561
    • Dunkel IJ, Finlay JL. High-dose chemotherapy with autologous stem cell rescue for brain tumors. Crit. Rev. Oncol. Hematol. 41(2), 197-204 (2002). (Pubitemid 34150130)
    • (2002) Critical Reviews in Oncology/Hematology , vol.41 , Issue.2 , pp. 197-204
    • Dunkel, I.J.1    Finlay, J.L.2
  • 139
    • 77952198779 scopus 로고    scopus 로고
    • High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma
    • Dunkel IJ, Gardner SL, Garvin JH Jr, Goldman S, Shibata S. High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma. J. Clin. Oncol. 12(3), 297-303 (2010).
    • (2010) J. Clin. Oncol. , vol.12 , Issue.3 , pp. 297-303
    • Dunkel, I.J.1    Gardner, S.L.2    Garvin Jr., J.H.3    Goldman, S.4    Shibata, S.5
  • 140
    • 68949085460 scopus 로고    scopus 로고
    • Randomized Phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma
    • Clarke JL, Iwamoto FM, Sul J et al. Randomized Phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma. J. Clin. Oncol. 27(23), 3861-3867 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.23 , pp. 3861-3867
    • Clarke, J.L.1    Iwamoto, F.M.2    Sul, J.3
  • 141
    • 29844433011 scopus 로고    scopus 로고
    • Intra-arterial chemotherapy of primary brain tumors
    • Newton HB. Intra-arterial chemotherapy of primary brain tumors. Curr. Treat. Options Oncol. 6(6), 519-530 (2005). (Pubitemid 43033781)
    • (2005) Current Treatment Options in Oncology , vol.6 , Issue.6 , pp. 519-530
    • Newton, H.B.1
  • 142
    • 4344691713 scopus 로고    scopus 로고
    • Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors
    • Warren K, Gervais A, Aikin A, Egorin M, Balis FM. Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors. Cancer Chemother. Pharmacol. 54(3), 206-212 (2004). (Pubitemid 39141736)
    • (2004) Cancer Chemotherapy and Pharmacology , vol.54 , Issue.3 , pp. 206-212
    • Warren, K.1    Gervais, A.2    Aikin, A.3    Egorin, M.4    Balis, F.M.5
  • 143
    • 0034061487 scopus 로고    scopus 로고
    • Pharmacokinetics of carboplatin administered in combination with the bradykinin agonist Cereport (RMP-7) for the treatment of brain tumours
    • Thomas HD, Lind MJ, Ford J, Bleehen N, Calvert AH, Boddy AV. Pharmacokinetics of carboplatin administered in combination with the bradykinin agonist Cereport (RMP-7) for the treatment of brain tumours. Cancer Chemother. Pharmacol. 45(4), 284 (2000).
    • (2000) Cancer Chemother. Pharmacol. , vol.45 , Issue.4 , pp. 284
    • Thomas, H.D.1    Lind, M.J.2    Ford, J.3    Bleehen, N.4    Calvert, A.H.5    Boddy, A.V.6
  • 145
    • 0033959628 scopus 로고    scopus 로고
    • Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model
    • Moore A, Marecos E, Bogdanov A, Weissleder R. Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model. Radiology 214, 568-574 (2000). (Pubitemid 30077721)
    • (2000) Radiology , vol.214 , Issue.2 , pp. 568-574
    • Moore, A.1    Marecos, E.2    Bogdanov Jr., A.3    Weissleder, R.4
  • 146
    • 0033974507 scopus 로고    scopus 로고
    • Osmotic opening of the blood-brain barrier: Principles, mechanism, and therapeutic applications
    • Rapoport SI. Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications. Cell. Mol. Neurobiol. 20(2), 217 (2000).
    • (2000) Cell. Mol. Neurobiol. , vol.20 , Issue.2 , pp. 217
    • Rapoport, S.I.1
  • 147
    • 0035300546 scopus 로고    scopus 로고
    • Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature
    • Kong G, Braun RD, Dewhirst MW. Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature. Cancer Res. 61(7), 3027-3032 (2001). (Pubitemid 32691950)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 3027-3032
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 149
    • 0038641304 scopus 로고    scopus 로고
    • Gadolinium-labeled dendrimers as biometric nanoprobes to detect vascular permeability
    • Yordanov AT, Kobayashi H, English SJ et al. Gadolinium-labeled dendrimers as biometric nanoprobes to detect vascular permeability. J. Mater. Chem. 13(7), 1523-1525 (2003).
    • (2003) J. Mater. Chem. , vol.13 , Issue.7 , pp. 1523-1525
    • Yordanov, A.T.1    Kobayashi, H.2    English, S.J.3
  • 150
    • 0029585915 scopus 로고
    • Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: Biodistribution and therapeutic efficacy
    • Siegal T, Horowitz A, Gabizon A. Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy. J. Neurosurg. 83(6), 1029-1037 (1995). (Pubitemid 26048143)
    • (1995) Journal of Neurosurgery , vol.83 , Issue.6 , pp. 1029-1037
    • Siegal, T.1    Horowitz, A.2    Gabizon, A.3
  • 151
    • 0030770632 scopus 로고    scopus 로고
    • Liposome-mediated therapy of intracranial brain tumors in a rat model
    • DOI 10.1023/A:1012136925030
    • Sharma US, Sharma A, Chau RI, Straubinger RM. Liposome-mediated therapy of intracranial brain tumors in a rat model. Pharm. Res. 14(8), 992-998 (1997). (Pubitemid 27371396)
    • (1997) Pharmaceutical Research , vol.14 , Issue.8 , pp. 992-998
    • Sharma, U.S.1    Sharma, A.2    Chau, R.I.3    Straubinger, R.M.4
  • 153
    • 0035477616 scopus 로고    scopus 로고
    • Long-term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin
    • DOI 10.1002/1097-0142(20011001)92:7<1936::AID-CNCR1712>3.0.CO;2-H
    • Fabel K, Dietrich J, Hau P et al. Long-term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin. Cancer 92(7), 1936-1942 (2001). (Pubitemid 32952514)
    • (2001) Cancer , vol.92 , Issue.7 , pp. 1936-1942
    • Fabel, K.1    Dietrich, J.2    Hau, P.3    Wismeth, C.4    Winner, B.5    Przywara, S.6    Steinbrecher, A.7    Ullrich, W.8    Bogdahn, U.9
  • 154
    • 0141927263 scopus 로고    scopus 로고
    • Stealth liposomes and long circulating nanoparticles: Critical issues in pharmacokinetics, opsonization and protein-binding properties
    • DOI 10.1016/S0163-7827(03)00033-X
    • Moghimi SM, Szebeni J. Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog. Lipid Res. 42(6), 463-478 (2003). (Pubitemid 37237636)
    • (2003) Progress in Lipid Research , vol.42 , Issue.6 , pp. 463-478
    • Moghimi, S.M.1    Szebeni, J.2
  • 155
    • 40849138014 scopus 로고    scopus 로고
    • Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes
    • Ishida T, Kiwada H. Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes. Int. J. Pharm. 354(1-2), 56-62 (2008).
    • (2008) Int. J. Pharm. , vol.354 , Issue.1-2 , pp. 56-62
    • Ishida, T.1    Kiwada, H.2
  • 158
    • 34249821046 scopus 로고    scopus 로고
    • Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu
    • DOI 10.1158/1078-0432.CCR-06-2240
    • Koyama Y, Hama Y, Urano Y, Nguyen DM, Choyke PL, Kobayashi H. Spectral fluorescence molecular imaging of lung metastases targeting HER2/neu. Clin. Cancer Res. 13(10), 2936-2945 (2007). (Pubitemid 46849568)
    • (2007) Clinical Cancer Research , vol.13 , Issue.10 , pp. 2936-2945
    • Koyama, Y.1    Hama, Y.2    Urano, Y.3    Nguyen, D.M.4    Choyke, P.L.5    Kobayashi, H.6
  • 160
    • 33750936437 scopus 로고    scopus 로고
    • A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
    • Lee CC, Gillies ER, Fox ME et al. A single dose of doxorubicin- functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc. Natl Acad. Sci. USA 103(45), 16649 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.45 , pp. 16649
    • Lee, C.C.1    Gillies, E.R.2    Fox, M.E.3
  • 161
    • 0023447252 scopus 로고
    • Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
    • Felgner PL, Gadek TR, Holm M et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl Acad. Sci. USA 84(21), 7413-7417 (1987).
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , Issue.21 , pp. 7413-7417
    • Felgner, P.L.1    Gadek, T.R.2    Holm, M.3
  • 162
    • 38049156027 scopus 로고    scopus 로고
    • Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes
    • Herce HD, Garcia AE. Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes. Proc. Natl Acad. Sci. USA 104(52), 20805-20810 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.52 , pp. 20805-20810
    • Herce, H.D.1    Garcia, A.E.2
  • 163
    • 57149110011 scopus 로고    scopus 로고
    • CNS delivery via adsorptive transcytosis
    • Herve F, Ghinea N, Scherrmann JM. CNS delivery via adsorptive transcytosis. AAPS J. 10(3), 455 (2008).
    • (2008) AAPS J. , vol.10 , Issue.3 , pp. 455
    • Herve, F.1    Ghinea, N.2    Scherrmann, J.M.3
  • 164
    • 77952901022 scopus 로고    scopus 로고
    • Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
    • Sugahara KN, Teesalu T, Karmali PP et al. Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs. Science 328(5981), 1031-1035 (2010).
    • (2010) Science , vol.328 , Issue.5981 , pp. 1031-1035
    • Sugahara, K.N.1    Teesalu, T.2    Karmali, P.P.3
  • 165
    • 85025321935 scopus 로고
    • The structure of apoferritin: Molecular size, shape and symmetry from x-ray data
    • Harrison PM. The structure of apoferritin: molecular size, shape and symmetry from x-ray data. J. Mol. Biol. 6(5), 404-422 (1963).
    • (1963) J. Mol. Biol. , vol.6 , Issue.5 , pp. 404-422
    • Harrison, P.M.1
  • 166
    • 0013787139 scopus 로고
    • The distribution within the brain of ferritin injected into cerebrospinal fluid compartments. I. Ependymal distribution
    • Brightman MW. The distribution within the brain of ferritin injected into cerebrospinal fluid compartments. I. Ependymal distribution. J. Cell Biol. 26(1), 99-123 (1965).
    • (1965) J. Cell Biol. , vol.26 , Issue.1 , pp. 99-123
    • Brightman, M.W.1
  • 167
    • 10044290943 scopus 로고    scopus 로고
    • The hydrodynamic radii of macromolecules and their effect on red blood cell aggregation
    • DOI 10.1529/biophysj.104.047746
    • Armstrong JK, Wenby RB, Meiselman HJ, Fisher TC. The hydrodynamic radii of macromolecules and their effect on red blood cell aggregation. Biophys. J. 87(6), 4259-4270 (2004). (Pubitemid 39602928)
    • (2004) Biophysical Journal , vol.87 , Issue.6 , pp. 4259-4270
    • Armstrong, J.K.1    Wenby, R.B.2    Meiselman, H.J.3    Fisher, T.C.4
  • 169
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size
    • Yuan F, Dellian M, Fukumura D et al. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. 55(17), 3752 (1995).
    • (1995) Cancer Res. , vol.55 , Issue.17 , pp. 3752
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3
  • 170
    • 0028304405 scopus 로고
    • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
    • Yuan F, Leunig M, Huang SK, Berk DA, Papahadjopoulos D, Jain RK. Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res. 54(13), 3352-3356 (1994). (Pubitemid 24225946)
    • (1994) Cancer Research , vol.54 , Issue.13 , pp. 3352-3356
    • Yuan, F.1    Leunig, M.2    Huang, S.K.3    Berk, D.A.4    Papahadjopoulos, D.5    Jain, R.K.6
  • 174
    • 13844262865 scopus 로고    scopus 로고
    • Distribution in brain of liposomes after convection enhanced delivery; Modulation by particle charge, particle diameter, and presence of steric coating
    • DOI 10.1016/j.brainres.2004.12.007
    • MacKay JA, Deen DF, Szoka FC Jr. Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating. Brain Res. 1035(2), 139-153 (2005). (Pubitemid 40250186)
    • (2005) Brain Research , vol.1035 , Issue.2 , pp. 139-153
    • MacKay, J.A.1    Deen, D.F.2    Szoka Jr., F.C.3
  • 175
    • 32944474182 scopus 로고    scopus 로고
    • VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
    • Kamba T, Tam BYY, Hashizume H et al. VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am. J. Physiol. Heart Circ. Physiol. 290(2), H560-576 (2006).
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.29 , Issue.2
    • Kamba, T.1    Byy, T.2    Hashizume, H.3
  • 177
    • 0021972672 scopus 로고
    • Endothelial fenestral diaphragms: A quick-freeze, deep-etch study
    • DOI 10.1083/jcb.100.2.418
    • Bearer EL, Orci L, Sors P. Endothelial fenestral diaphragms: a quick-freeze, deep-etch study. J. Cell Biol. 100(2), 418-428 (1985). (Pubitemid 15173247)
    • (1985) Journal of Cell Biology , vol.100 , Issue.2 , pp. 418-428
    • Bearer, E.L.1    Orci, L.2    Sors, P.3
  • 178
    • 0018818410 scopus 로고
    • Ultrastructure of fenestrations in endothelial choriocapillaries of the rabbit - A freeze-fracturing study
    • Melamed S, Ben-Sira I, Ben-Shaul Y. Ultrastructure of fenestrations in endothelial choriocapillaries of the rabbit - a freeze-fracturing study. Br. J. Ophthalmol. 64(7), 537-543 (1980). (Pubitemid 10059099)
    • (1980) British Journal of Ophthalmology , vol.64 , Issue.7 , pp. 537-543
    • Melamed, S.1    Ben-Sira, I.2    Ben-Shaul, Y.3
  • 179
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res. 46(12 I), 6387-6392 (1986). (Pubitemid 17221789)
    • (1986) Cancer Research , vol.46 , Issue.12 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 180
    • 60749108001 scopus 로고    scopus 로고
    • Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
    • Maeda H, Bharate GY, Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur. J. Pharm. Biopharm. 71(3), 409 (2009).
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , Issue.3 , pp. 409
    • Maeda, H.1    Bharate, G.Y.2    Daruwalla, J.3
  • 181
    • 0024235612 scopus 로고
    • Protein binding of macromolecular anticancer agent SMANCS: Characterization of poly(styrene-co-maleic acid) derivatives as an albumin binding ligand
    • Kobayashi A, Oda T, Maeda H. Protein binding of macromolecular anticancer agent SMANCS: characterization of poly(styrene-co-maleic acid) derivatives as an albumin binding ligand. J. Bioact. Compat. Polym. 3(4), 319-333 (1988). (Pubitemid 19059729)
    • (1988) Journal of Bioactive and Compatible Polymers , vol.3 , Issue.4 , pp. 319-333
    • Kobayashi, A.1    Oda, T.2    Maeda, H.3
  • 182
    • 0023212748 scopus 로고
    • Binding to and internalization by cultured cells of neocarzinostatin and enhancement of its actions by conjugation with lipophilic styrene-maleic acid copolymer
    • Oda T, Maeda H. Binding to and internalization by cultured cells of neocarzinostatin and enhancement of its actions by conjugation with lipophilic styrene-maleic acid copolymer. Cancer Res. 47(12), 3206-3211 (1987). (Pubitemid 17082650)
    • (1987) Cancer Research , vol.47 , Issue.12 , pp. 3206-3211
    • Oda, T.1    Maeda, H.2
  • 183
    • 0023552720 scopus 로고
    • Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH
    • Oda T, Sato F, Maeda H. Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH. J. Natl Cancer. Inst. 79(6), 1205-1211 (1987). (Pubitemid 18036723)
    • (1987) Journal of the National Cancer Institute , vol.79 , Issue.6 , pp. 1205-1211
    • Oda, T.1    Sato, F.2    Maeda, H.3
  • 184
    • 0842285204 scopus 로고    scopus 로고
    • Site-Specific Conjugation of Boron-Containing Dendrimers to Anti-EGF Receptor Monoclonal Antibody Cetuximab (IMC-C225) and Its Evaluation as a Potential Delivery Agent for Neutron Capture Therapy
    • DOI 10.1021/bc0341674
    • Wu G, Barth RF, Yang W et al. Site-specific conjugation of boron-containing dendrimers to anti-EGF receptor monoclonal antibody cetuximab (IMC-C225) and its evaluation as a potential delivery agent for neutron capture therapy. Bioconj. Chem. 15(1), 185-194 (2003). (Pubitemid 38165994)
    • (2004) Bioconjugate Chemistry , vol.15 , Issue.1 , pp. 185-194
    • Wu, G.1    Barth, R.F.2    Yang, W.3    Chatterjee, M.4    Tjarks, W.5    Ciesielski, M.J.6    Fenstermaker, R.A.7
  • 185
    • 11144336676 scopus 로고    scopus 로고
    • Pharmacokinetics of liposomal doxorubicin (TLC-D99; Myocet) in patients with solid tumors: An open-label, single-dose study
    • DOI 10.1007/s00280-004-0825-y
    • Mross K, Niemann B, Massing U et al. Pharmacokinetics of liposomal doxorubicin (TLC-D99; Myocet™) in patients with solid tumors: an open-label, single-dose study. Cancer Chemother. Pharmacol. 54(6), 514-524 (2004). (Pubitemid 40022247)
    • (2004) Cancer Chemotherapy and Pharmacology , vol.54 , Issue.6 , pp. 514-524
    • Mross, K.1    Niemann, B.2    Massing, U.3    Drevs, J.4    Unger, C.5    Bhamra, R.6    Swenson, C.E.7
  • 186
    • 74549221384 scopus 로고    scopus 로고
    • A Phase II clinical trial of NAB-Paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanoma
    • Hersh EM, O'Day SJ, Ribas A et al. A Phase II clinical trial of NAB-Paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanoma. Cancer 116(1), 155-163 (2010).
    • (2010) Cancer , vol.116 , Issue.1 , pp. 155-163
    • Hersh, E.M.1    O'day, S.J.2    Ribas, A.3
  • 188
    • 0035999704 scopus 로고    scopus 로고
    • Polyester dendritic systems for drug delivery applications: In vitro and in vivo evaluation
    • DOI 10.1021/bc010103m
    • Padilla De Jesus OL, Ihre HR, Gagne L, Frechet JMJ, Szoka FC. Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation. Bioconj. Chem.13(3), 453-461 (2002). (Pubitemid 34535938)
    • (2002) Bioconjugate Chemistry , vol.13 , Issue.3 , pp. 453-461
    • Padilla De Jesus, O.L.1    Ihre, H.R.2    Gagne, L.3    Frechet, J.M.J.4    Szoka Jr., F.C.5
  • 189
    • 33847017288 scopus 로고    scopus 로고
    • Dendrimers as multipurpose nanodevices for oncology drug delivery and diagnostic imaging
    • Tomalia DA, Reyna LA, Svenson S. Dendrimers as multipurpose nanodevices for oncology drug delivery and diagnostic imaging. Biochem. Soc. Trans. 35(Pt 1), 61-67 (2007).
    • (2007) Biochem. Soc. Trans. , vol.35 , Issue.PART 1 , pp. 61-67
    • Tomalia, D.A.1    Reyna, L.A.2    Svenson, S.3
  • 190
    • 0036201994 scopus 로고    scopus 로고
    • 153Gd-folate dendrimer, generation = 4, in mice with folate-receptor positive and negative ovarian tumor xenografts
    • DOI 10.1097/00004424-200204000-00005
    • Konda SD, Wang S, Brechbiel M, Weiner EC. Biodistribution of a 153Gd-folate dendrimer, generation = 4, in mice with folate-receptor positive and negative ovarian tumor xenografts. Invest. Radiol. 37(4), 199-204 (2002). (Pubitemid 34259729)
    • (2002) Investigative Radiology , vol.37 , Issue.4 , pp. 199-204
    • Konda, S.D.1    Wang, S.2    Brechbiel, M.3    Wiener, E.C.4
  • 191
    • 75149190139 scopus 로고    scopus 로고
    • Antiglioma therapy with temozolomide and status of the DNA-repair gene MGMT
    • Fukushima T, Takeshima H, Kataoka H. Antiglioma therapy with temozolomide and status of the DNA-repair gene MGMT. Anticancer Res. 29(11), 4845-4854 (2009)
    • (2009) Anticancer Res. , vol.29 , Issue.11 , pp. 4845-4854
    • Fukushima, T.1    Takeshima, H.2    Kataoka, H.3
  • 192
    • 0023552720 scopus 로고
    • Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH
    • Oda T, Sato F, Maeda H. Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH. J. Natl Cancer. Inst. 79(6), 1205-1211 (1987). (Pubitemid 18036723)
    • (1987) Journal of the National Cancer Institute , vol.79 , Issue.6 , pp. 1205-1211
    • Oda, T.1    Sato, F.2    Maeda, H.3
  • 193
    • 0842285204 scopus 로고    scopus 로고
    • Site-Specific Conjugation of Boron-Containing Dendrimers to Anti-EGF Receptor Monoclonal Antibody Cetuximab (IMC-C225) and Its Evaluation as a Potential Delivery Agent for Neutron Capture Therapy
    • DOI 10.1021/bc0341674
    • Wu G, Barth RF, Yang W et al. Site-specific conjugation of boron-containing dendrimers to anti-EGF receptor monoclonal antibody cetuximab (IMC-C225) and its evaluation as a potential delivery agent for neutron capture therapy. Bioconj. Chem. 15(1), 185-194 (2003). (Pubitemid 38165994)
    • (2004) Bioconjugate Chemistry , vol.15 , Issue.1 , pp. 185-194
    • Wu, G.1    Barth, R.F.2    Yang, W.3    Chatterjee, M.4    Tjarks, W.5    Ciesielski, M.J.6    Fenstermaker, R.A.7
  • 194
    • 11144336676 scopus 로고    scopus 로고
    • Pharmacokinetics of liposomal doxorubicin (TLC-D99; Myocet) in patients with solid tumors: An open-label, single-dose study
    • DOI 10.1007/s00280-004-0825-y
    • Mross K, Niemann B, Massing U et al. Pharmacokinetics of liposomal doxorubicin (TLC-D99; Myocet™) in patients with solid tumors: an open-label, single-dose study. Cancer Chemother. Pharmacol. 54(6), 514-524 (2004). (Pubitemid 40022247)
    • (2004) Cancer Chemotherapy and Pharmacology , vol.54 , Issue.6 , pp. 514-524
    • Mross, K.1    Niemann, B.2    Massing, U.3    Drevs, J.4    Unger, C.5    Bhamra, R.6    Swenson, C.E.7
  • 195
    • 74549221384 scopus 로고    scopus 로고
    • A Phase II clinical trial of NAB-Paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanoma
    • Hersh EM, O'Day SJ, Ribas A et al. A Phase II clinical trial of NAB-Paclitaxel in previously treated and chemotherapy-naive patients with metastatic melanoma. Cancer 116(1), 155-163 (2010).
    • (2010) Cancer , vol.116 , Issue.1 , pp. 155-163
    • Hersh, E.M.1    O'day, S.J.2    Ribas, A.3
  • 197
    • 0035999704 scopus 로고    scopus 로고
    • Polyester dendritic systems for drug delivery applications: In vitro and in vivo evaluation
    • DOI 10.1021/bc010103m
    • Padilla De Jesus OL, Ihre HR, Gagne L, Frechet JMJ, Szoka FC. Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation. Bioconj. Chem.13(3), 453-461 (2002). (Pubitemid 34535938)
    • (2002) Bioconjugate Chemistry , vol.13 , Issue.3 , pp. 453-461
    • Padilla De Jesus, O.L.1    Ihre, H.R.2    Gagne, L.3    Frechet, J.M.J.4    Szoka Jr., F.C.5
  • 198
    • 33847017288 scopus 로고    scopus 로고
    • Dendrimers as multipurpose nanodevices for oncology drug delivery and diagnostic imaging
    • Tomalia DA, Reyna LA, Svenson S. Dendrimers as multipurpose nanodevices for oncology drug delivery and diagnostic imaging. Biochem. Soc. Trans. 35(Pt 1), 61-67 (2007).
    • (2007) Biochem. Soc. Trans. , vol.35 , Issue.PART 1 , pp. 61-67
    • Tomalia, D.A.1    Reyna, L.A.2    Svenson, S.3
  • 199
    • 0036201994 scopus 로고    scopus 로고
    • 153Gd-folate dendrimer, generation = 4, in mice with folate-receptor positive and negative ovarian tumor xenografts
    • DOI 10.1097/00004424-200204000-00005
    • Konda SD, Wang S, Brechbiel M, Weiner EC. Biodistribution of a 153Gd-folate dendrimer, generation = 4, in mice with folate-receptor positive and negative ovarian tumor xenografts. Invest. Radiol. 37(4), 199-204 (2002). (Pubitemid 34259729)
    • (2002) Investigative Radiology , vol.37 , Issue.4 , pp. 199-204
    • Konda, S.D.1    Wang, S.2    Brechbiel, M.3    Wiener, E.C.4
  • 200
    • 75149190139 scopus 로고    scopus 로고
    • Antiglioma therapy with temozolomide and status of the DNA-repair gene MGMT
    • Fukushima T, Takeshima H, Kataoka H. Antiglioma therapy with temozolomide and status of the DNA-repair gene MGMT. Anticancer Res. 29(11), 4845-4854 (2009).
    • (2009) Anticancer Res. , vol.29 , Issue.11 , pp. 4845-4854
    • Fukushima, T.1    Takeshima, H.2    Kataoka, H.3


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