Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors

Cancer Chemotherapy and Pharmacology

Volumn 54, Issue 3, 2004, Pages 206-212

  Warren, Katherine ^a   Gervais, Anne ^b   Aikin, Alberta ^a   Egorin, Merrill ^b   Balis, Frank M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Brain; Carboplatin; Lobradimil; Pediatric; Pharmacokinetics

Indexed keywords

ANTINEOPLASTIC AGENT; BRADYKININ RECEPTOR AGONIST; CARBOPLATIN; LOBRADIMIL; PLATINUM;

ADOLESCENT; ADULT; AREA UNDER THE CURVE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BLOOD SAMPLING; BONE MARROW SUPPRESSION; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE CALCULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; MALE; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL;

EID: 4344691713     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-004-0791-4     Document Type: Article

References (24)

1. Elliott PJ, Hayward NJ, Huff MR, et al (1996) Unlocking the blood-brain barrier: a role for RMP-7 in brain tumor therapy. Exp Neurol 141:214-224
2. Raymond JJ, Robertson DM, Dinsdale HB (1986) Pharmacological modification of bradykinin induced breakdown of the blood-brain barrier. Can J Physiol Pharmacol 13:214-220
3. Liu Y, Hashizume L, Chen Z, et al (2001) Correlation between bradykinin-induced blood-tumor barrier permeability and B2 receptor expression in experimental brain tumors. Neurol Res 23:379
4. Inamura T, Black KL (1994) Bradykinin selectively opens blood-tumor barrier in experimental brain tumors. J Cereb Blood Flow Metab 14:862-870
5. Matsukado K, Inamura T, Nakano S, et al (1996) Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7. Neurosurgery 39:125-133
6. Elliott PJ, Hayward NJ, Dean RL, et al (1996) Intravenous RMP-7 selectively increases uptake of carboplatin into rat brain tumors. Cancer Res 56:3998-4005
7. Inamura T, Nomura T, Bartus RT, et al (1994) Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors. J Neurosurg 81:752-758
8. Warren KE, Patel MC, Aikin AA, et al (2001) Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors. Cancer Chemother Pharmacol 48:275-282
9. Harland S, Newell D, Siddik Z, et al (1984) Pharmacokinetics of cis-diammine-1,1-cyclobutane dicarboxylate platinum (II) in patients with normal and impaired renal function. Cancer Res 44:1693-1697
10. Egorin M, van Echo D, Tipping S, et al (1984) Pharmacokinetics and dosage reduction of cis-diammine (1,1-cyclobutanedicarboxylato)platinum in patients with impaired renal function. Cancer Res 44:5432-5438
11. Calvert A, Newell D, Gumbrell L, et al (1989) Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 7:1748-1756
12. Newell D, Pearson A, Balmanno K, et al (1993) Carboplatin pharmacokinetics in children: the development of a pediatric dosing formula. J Clin Oncol 11:2314-2323
13. Marina N, Rodman J, Shema S, et al (1993) Phase I study of escalating targeted doses of carboplatin combined with ifosfamide and etoposide in children with relapsed solid tumors. J Clin Oncol 11:554-560
14. Marina N, Rodman JH, Murry DJ, et al (1994) Phase 1 study of escalating targeted doses of carboplatin combined with ifosfamide and etoposide in treatment of newly diagnosed pediatric solid tumors. J Natl Cancer Inst 86:554
15. Thomas HD, Lind MJ, Ford J, et al (2000) Pharmacokinetics of carboplatin administered in combination with the bradykinin agonist cereport (RMP-7) for the treatment of brain tumors. Cancer Chemother Pharmacol 45:284-290
16. Spierto FW, MacNeil ML, Burtis CA (1979) The effect of temperature and wavelength on the measurement of creatinine with the Jaffe procedure. Clin Biochem 12:18
17. Russell C, Bischoff P, Kantzen F, et al (1985) Measurement of glomerular filtration rate: single injection plasma clearance method without urine collection. J Nucl Med 26:1243-1247
18. DuBois D, Dubois E (1916) Formula to estimate the approximate surface area if height and weight be known. Arch Intern Med 17:863
19. Ghazal-Aswad S, Calvert AH, Newell DR 1996) A single-sample assay for the estimation of the area under the free carboplatin plasma concentration versus time curve. Cancer Chemother Pharmacol 37:429-434
20. Thomas H, Boddy A, English M, et al (2000) Prospective validation of renal function-based carboplatin dosing in children with cancer: a United Kingdom Children's Cancer Study Group trial. J Clin Oncol 18:3614-3621
21. Riccardi R, Riccardi A, Lasorella A, et al (1994) Clinical pharmacokinetics of carboplatin in children. Cancer Chemother Pharmacol 33:477-483
22. Matsumura Y, Tadano K, Yamasaki T (1999) Renal haemodynamic and excretory responses to bradykinin in anesthetized dogs. Clin Exp Pharmacol Physiol 26:645
23. Granger JP, Hall JE (1985) Acute and chronic actions of bradykinin on renal function and arterial pressure. Am J Physiol 248 (1 Pt 2):F87
24. Lortie M, Regoli D, Rhaleb NE, et al (1992) The role of B1-and B2-kinin receptors in the renal tubular and hemodynamic response to bradykinin. Am J Physiol 262 (1 Pt 2):R72