Fine mapping of the insulin-induced gene 2 identifies a variant associated with LDL cholesterol and total apolipoprotein B levels

Circulation: Cardiovascular Genetics

Volumn 3, Issue 5, 2010, Pages 454-461

  Do, Ron ^a   Bailey, Swneke D ^a   Pare, Guillaume ^a,b,g   Montpetit, Alexandre ^b   Desbiens, Katia ^c   Hudson, Thomas J ^b,h   Yusuf, Salim ^g   Bouchard, Claude ^d   Gaudet, Daniel ^e   Pérusse, Louis ^f   Anand, Sonia ^g   Vohl, Marie Claude ^f   Pastinen, Tomi ^a,b   Engert, James C ^a,b,c  

^a Department of Human Genetics ^*  (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^d PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

^f UNIVERSITÉ LAVAL   (Canada)

^g MCMASTER UNIVERSITY   (Canada)

^h ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

Cholesterol; INSIG2; LDL cholesterol; Single nucleotide polymorphism; Total apoB

Indexed keywords

APOLIPOPROTEIN B; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PROTEIN SH3;

ADULT; ARTICLE; BASE PAIRING; BODY MASS; CONTROLLED STUDY; EUROPE; FEMALE; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HYPOTHESIS; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH ASIA;

ADULT; ANIMALS; APOLIPOPROTEINS B; CHOLESTEROL, LDL; CHROMOSOME MAPPING; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; MIDDLE AGED; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 78649384392     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.109.917039     Document Type: Article

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