-
1
-
-
77951957803
-
-
World Health Organization World malaria report http://www.searo.who.int/ LinkFiles/Reports-mal2009-report.pdf 2009
-
(2009)
World Malaria Report
-
-
-
2
-
-
20944441296
-
In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines
-
T.W. Shearer, M.P. Kozar, M.T. O'Neil, P.L. Smith, G.A. Schiehser, and D.P. Jacobus In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines Journal of Medicinal Chemistry 48 2005 2805 2813
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, pp. 2805-2813
-
-
Shearer, T.W.1
Kozar, M.P.2
O'Neil, M.T.3
Smith, P.L.4
Schiehser, G.A.5
Jacobus, D.P.6
-
3
-
-
64349102737
-
Rational modification of a candidate cancer drug for use against Chagas disease
-
J.M. Kraus, C.L.M.J. Verlinde, M. Karimi, G.I. Lepesheva, M.H. Gelb, and F.S. Buckner Rational modification of a candidate cancer drug for use against Chagas disease Journal of Medicinal Chemistry 52 2009 1639 1647
-
(2009)
Journal of Medicinal Chemistry
, vol.52
, pp. 1639-1647
-
-
Kraus, J.M.1
Verlinde, C.L.M.J.2
Karimi, M.3
Lepesheva, G.I.4
Gelb, M.H.5
Buckner, F.S.6
-
4
-
-
0142227145
-
Specific chemotherapy of Chagas disease: Controversies and advances
-
J.A. Urbina, and R. Docampo Specific chemotherapy of Chagas disease: controversies and advances Trends in Parasitology 19 2003 495 501
-
(2003)
Trends in Parasitology
, vol.19
, pp. 495-501
-
-
Urbina, J.A.1
Docampo, R.2
-
5
-
-
38949100064
-
Trypanocidal activity of a new pterocarpan and other secondary metabolites of plants from northeastern Brazil flora
-
N.C. Vieira, L.S. Espindola, J.M. Santana, M.L. Veras, O.D.L. Pessoa, and S.M. Pinheiro Trypanocidal activity of a new pterocarpan and other secondary metabolites of plants from northeastern Brazil flora Bioorganic & Medicinal Chemistry 16 2008 1676 1682
-
(2008)
Bioorganic & Medicinal Chemistry
, vol.16
, pp. 1676-1682
-
-
Vieira, N.C.1
Espindola, L.S.2
Santana, J.M.3
Veras, M.L.4
Pessoa, O.D.L.5
Pinheiro, S.M.6
-
6
-
-
30444438035
-
Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis
-
E.L. Ravaschino, R. Docampo, and J.B. Rodriguez Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis Journal of Medicinal Chemistry 49 2006 426 435
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 426-435
-
-
Ravaschino, E.L.1
Docampo, R.2
Rodriguez, J.B.3
-
7
-
-
32344435160
-
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole
-
G. Benaim, J.M. Sanders, Y. Garcia-Marchan, C. Colina, R. Lira, and A.R. Caldera Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole Journal of Medicinal Chemistry 49 2006 892 899
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 892-899
-
-
Benaim, G.1
Sanders, J.M.2
Garcia-Marchan, Y.3
Colina, C.4
Lira, R.5
Caldera, A.R.6
-
8
-
-
37249035718
-
Adenosine deaminase activity in sera of patients with visceral leishmaniasis in India
-
K. Tripathi, R. Kumar, K. Bharti, P. Kumar, R. Shrivastav, and S. Sundar Adenosine deaminase activity in sera of patients with visceral leishmaniasis in India Clinica Chimica Acta 388 2008 135 138
-
(2008)
Clinica Chimica Acta
, vol.388
, pp. 135-138
-
-
Tripathi, K.1
Kumar, R.2
Bharti, K.3
Kumar, P.4
Shrivastav, R.5
Sundar, S.6
-
9
-
-
0034597543
-
Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: Elucidation of a novel binding mode for a 2-amino-N6-substituted adenosine
-
J.C. Bressi, J. Choe, M.T. Hough, F.S. Buckner, W.C.V. Voorhis, and C.L.M.J. Verlinde Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N6-substituted adenosine Journal of Medicinal Chemistry 43 2000 4135 4150
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, pp. 4135-4150
-
-
Bressi, J.C.1
Choe, J.2
Hough, M.T.3
Buckner, F.S.4
Voorhis, W.C.V.5
Verlinde, C.L.M.J.6
-
10
-
-
0030883946
-
The current status of antiparasite chemotherapy
-
S.L. Croft The current status of antiparasite chemotherapy Parasitology 114 1997 S3 15
-
(1997)
Parasitology
, vol.114
, pp. 3-15
-
-
Croft, S.L.1
-
11
-
-
33751080094
-
Drug discovery and development for neglected parasitic diseases
-
A.R. Renslo, and J.H. McKerrow Drug discovery and development for neglected parasitic diseases Nature Chemical Biology 2 2006 701 710
-
(2006)
Nature Chemical Biology
, vol.2
, pp. 701-710
-
-
Renslo, A.R.1
McKerrow, J.H.2
-
12
-
-
0024148694
-
Mitochondrial membrane potential in living cells
-
L.B. Chen Mitochondrial membrane potential in living cells Annual Review of Cell Biology 4 1988 155 158
-
(1988)
Annual Review of Cell Biology
, vol.4
, pp. 155-158
-
-
Chen, L.B.1
-
13
-
-
0037186472
-
Rhodacyanine dyes as antimalarials. 1. Preliminary evaluation of their activity and toxicity
-
K. Takasu, H. Inoue, H.S. Kim, M. Suzuki, T. Shishido, and Y. Wataya Rhodacyanine dyes as antimalarials. 1. Preliminary evaluation of their activity and toxicity Journal of Medicinal Chemistry 45 2002 995 998
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, pp. 995-998
-
-
Takasu, K.1
Inoue, H.2
Kim, H.S.3
Suzuki, M.4
Shishido, T.5
Wataya, Y.6
-
14
-
-
0141563671
-
Parallel synthesis of antimalarial rhodacyanine dyes by the combination of three components in one pot
-
K. Takasu, H. Terauchi, H. Inoue, H.S. Kim, Y. Wataya, and M. Ihara Parallel synthesis of antimalarial rhodacyanine dyes by the combination of three components in one pot Journal of Combinatorial Chemistry 5 2003 211 214
-
(2003)
Journal of Combinatorial Chemistry
, vol.5
, pp. 211-214
-
-
Takasu, K.1
Terauchi, H.2
Inoue, H.3
Kim, H.S.4
Wataya, Y.5
Ihara, M.6
-
15
-
-
33746729457
-
Synthesis and antimalarial efficacy of aza-fused rhodacyanines in vitro and in the P. berghei mouse model
-
K. Takasu, K. Pudhom, M. Kaiser, R. Brun, and M. Ihara Synthesis and antimalarial efficacy of aza-fused rhodacyanines in vitro and in the P. berghei mouse model Journal of Medicinal Chemistry 49 2006 4795 4798
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 4795-4798
-
-
Takasu, K.1
Pudhom, K.2
Kaiser, M.3
Brun, R.4
Ihara, M.5
-
16
-
-
33751061441
-
Synthesis of three classes of rhodacyanine dyes and evaluation of their in vitro and in vivo antimalarial activity
-
K. Pudhom, K. Kasai, H. Terauchi, H. Inoue, M. Kaiser, and R. Brun Synthesis of three classes of rhodacyanine dyes and evaluation of their in vitro and in vivo antimalarial activity Bioorganic & Medicinal Chemistry 14 2006 8550 8563
-
(2006)
Bioorganic & Medicinal Chemistry
, vol.14
, pp. 8550-8563
-
-
Pudhom, K.1
Kasai, K.2
Terauchi, H.3
Inoue, H.4
Kaiser, M.5
Brun, R.6
-
17
-
-
65649152075
-
Synthesis and biological properties of a rhodacyanine derivative, SSJ-127, having high efficacy against malaria protozoa
-
K. Pudhom, J.F. Ge, C. Arai, M. Yang, M. Kaiser, and S. Wittlin Synthesis and biological properties of a rhodacyanine derivative, SSJ-127, having high efficacy against malaria protozoa Heterocycles 77 2009 207 210
-
(2009)
Heterocycles
, vol.77
, pp. 207-210
-
-
Pudhom, K.1
Ge, J.F.2
Arai, C.3
Yang, M.4
Kaiser, M.5
Wittlin, S.6
-
18
-
-
34249101189
-
Synthesis and antimalarial property of orally active phenoxazinium salts
-
K. Takasu, T. Shimogama, C. Satoh, M. Kaiser, R. Brun, and M. Ihara Synthesis and antimalarial property of orally active phenoxazinium salts Journal of Medicinal Chemistry 50 2007 2281 2284
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, pp. 2281-2284
-
-
Takasu, K.1
Shimogama, T.2
Satoh, C.3
Kaiser, M.4
Brun, R.5
Ihara, M.6
-
19
-
-
41949110268
-
The convenient synthesis of zinc chloride-free 3,7-bis(dialkylamino) phenoxazinium salts
-
J.F. Ge, C. Arai, and M. Ihara The convenient synthesis of zinc chloride-free 3,7-bis(dialkylamino)phenoxazinium salts Dyes and Pigments 79 2008 22 39
-
(2008)
Dyes and Pigments
, vol.79
, pp. 22-39
-
-
Ge, J.F.1
Arai, C.2
Ihara, M.3
-
20
-
-
45749103716
-
Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives
-
J.F. Ge, C. Arai, M. Kaiser, S. Wittlin, R. Brun, and M. Ihara Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives Journal of Medicinal Chemistry 51 2008 3654 3658
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, pp. 3654-3658
-
-
Ge, J.F.1
Arai, C.2
Kaiser, M.3
Wittlin, S.4
Brun, R.5
Ihara, M.6
-
21
-
-
60049095945
-
Pharmacodynamics and pharmacokinetics study of phenoxazinium derivatives for antimalarial agent
-
M. Yang, J.F. Ge, C. Arai, I. Itoh, Q. Fu, and M. Ihara Pharmacodynamics and pharmacokinetics study of phenoxazinium derivatives for antimalarial agent Bioorganic & Medicinal Chemistry 17 2009 1481 1485
-
(2009)
Bioorganic & Medicinal Chemistry
, vol.17
, pp. 1481-1485
-
-
Yang, M.1
Ge, J.F.2
Arai, C.3
Itoh, I.4
Fu, Q.5
Ihara, M.6
-
22
-
-
0029987752
-
Mode of antimalarial effect of methylene blue and some of its analogues on plasmodium falcilarun in culture and their inhibition of P. vinckei and P. yoelii nigeriensis in vivo
-
H. Atamna, M. Krugliak, G. Shalmiev, E. Deharo, G. Pescarmona, and H. Ginsburg Mode of antimalarial effect of methylene blue and some of its analogues on plasmodium falcilarun in culture and their inhibition of P. vinckei and P. yoelii nigeriensis in vivo Biochemical Pharmacology 51 1996 693 700
-
(1996)
Biochemical Pharmacology
, vol.51
, pp. 693-700
-
-
Atamna, H.1
Krugliak, M.2
Shalmiev, G.3
Deharo, E.4
Pescarmona, G.5
Ginsburg, H.6
-
23
-
-
33750209732
-
Methylene blue for malaria in africa: Results from a dose-finding study in combination with chloroquine
-
P.E. Meissner, G. Mandi, B. Coulibaly, S. Witte, T. Tapsoba, and U. Mansmann Methylene blue for malaria in africa: results from a dose-finding study in combination with chloroquine Malaria Journal 5 84 2006 1 5
-
(2006)
Malaria Journal
, vol.5
, Issue.84
, pp. 1-5
-
-
Meissner, P.E.1
Mandi, G.2
Coulibaly, B.3
Witte, S.4
Tapsoba, T.5
Mansmann, U.6
-
24
-
-
67349154437
-
Phenothiazinium photosensitisers, part VI: Photobactericidal asymmetric derivatives
-
M. Wainwright, K. Meegan, C. Loughran, and R.M. Giddens Phenothiazinium photosensitisers, part VI: photobactericidal asymmetric derivatives Dyes and Pigments 82 2009 387 391
-
(2009)
Dyes and Pigments
, vol.82
, pp. 387-391
-
-
Wainwright, M.1
Meegan, K.2
Loughran, C.3
Giddens, R.M.4
-
25
-
-
0038181138
-
Phenothiazinium photosensitisers: Choices in synthesis and application
-
M. Wainwright, and R.M. Giddens Phenothiazinium photosensitisers: choices in synthesis and application Dyes and Pigments 57 2003 245 257
-
(2003)
Dyes and Pigments
, vol.57
, pp. 245-257
-
-
Wainwright, M.1
Giddens, R.M.2
-
26
-
-
30944446166
-
The synthesis and properties of unsymmetrical 3, 7-diaminophenothiazin-5- ium iodide salts: Potential photosensitisers for photodynamic therapy
-
S.A. Gorman, A.L. Bell, J. Griffiths, D. Roberts, and S.B. Brown The synthesis and properties of unsymmetrical 3, 7-diaminophenothiazin-5-ium iodide salts: potential photosensitisers for photodynamic therapy Dyes and Pigments 71 2006 153 160
-
(2006)
Dyes and Pigments
, vol.71
, pp. 153-160
-
-
Gorman, S.A.1
Bell, A.L.2
Griffiths, J.3
Roberts, D.4
Brown, S.B.5
-
27
-
-
78649332557
-
-
PCT patent, WO 2005/054217 A1; 2005 June 16
-
Brown SB, O'Grady GC, Griffiths J, Mellish KJ, Tunstall RG, Roberts DJH, et-al. Photophamica limited. Developments in biologically active methylene blue derivatives (2), PCT patent, WO 2005/054217 A1; 2005 June 16.
-
Photophamica Limited. Developments in Biologically Active Methylene Blue Derivatives
, Issue.2
-
-
Brown, S.B.1
O'Grady, G.C.2
Griffiths, J.3
Mellish, K.J.4
Tunstall, R.G.5
Roberts, D.J.H.6
-
28
-
-
84986492865
-
Ladder oligophenothiazines by direct thionation of N-arylanilino derivatives
-
F. Andreani, P.C. Bizzarri, C.D. Casa, M. Fiorini, and E. Salatelli Ladder oligophenothiazines by direct thionation of N-arylanilino derivatives Journal of Heterocyclic Chemistry 28 1991 295 299
-
(1991)
Journal of Heterocyclic Chemistry
, vol.28
, pp. 295-299
-
-
Andreani, F.1
Bizzarri, P.C.2
Casa, C.D.3
Fiorini, M.4
Salatelli, E.5
-
29
-
-
0033116353
-
Phenothiazine photosensitizers: Part 2. 3,7-bis(arylamino)phenothiazines
-
M. Wainwright, N.J. Grice, and L.E.C. Pye Phenothiazine photosensitizers: part 2. 3,7-bis(arylamino)phenothiazines Dyes and Pigments 42 1999 45 51
-
(1999)
Dyes and Pigments
, vol.42
, pp. 45-51
-
-
Wainwright, M.1
Grice, N.J.2
Pye, L.E.C.3
-
30
-
-
33947520525
-
Mercury(II)-methylene blue interactions: Complexation and metallate formation
-
M.M. Raj, A. Dharmaraja, S.J. Kavitha, K. Panchanatheswaran, and D.E. Lynch Mercury(II)-methylene blue interactions: complexation and metallate formation Inorganica Chimica Acta 360 2007 1799 1808
-
(2007)
Inorganica Chimica Acta
, vol.360
, pp. 1799-1808
-
-
Raj, M.M.1
Dharmaraja, A.2
Kavitha, S.J.3
Panchanatheswaran, K.4
Lynch, D.E.5
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