메뉴 건너뛰기




Volumn 128, Issue 6, 2010, Pages 609-614

PTEN transcript variants caused by illegitimate splicing in "aged" blood samples and EBV-transformed cell lines

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 78649324389     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-010-0886-4     Document Type: Article
Times cited : (9)

References (20)
  • 1
    • 33144470077 scopus 로고    scopus 로고
    • Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer
    • DOI 10.1093/hmg/ddi492
    • S Agrawal C Eng 2006 Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer Hum Mol Genet 15 777 787 1:CAS:528: DC%2BD28XhsF2mur4%3D 10.1093/hmg/ddi492 16436456 (Pubitemid 43264702)
    • (2006) Human Molecular Genetics , vol.15 , Issue.5 , pp. 777-787
    • Agrawal, S.1    Eng, C.2
  • 2
    • 0036534129 scopus 로고    scopus 로고
    • Alternative splicing: Multiple control mechanisms and involvement in human disease
    • DOI 10.1016/S0168-9525(01)02626-9, PII S0168952501026269
    • JF Caceres AR Kornblihtt 2002 Alternative splicing: multiple control mechanisms and involvement in human disease Trends Genet 18 186 193 1:CAS:528:DC%2BD38XisV2htb0%3D 10.1016/S0168-9525(01)02626-9 11932019 (Pubitemid 34273739)
    • (2002) Trends in Genetics , vol.18 , Issue.4 , pp. 186-193
    • Caceres, J.F.1    Kornblihtt, A.R.2
  • 3
    • 51849084360 scopus 로고    scopus 로고
    • The PTEN-PI3K pathway: Of feedbacks and cross-talks
    • 1:CAS:528:DC%2BD1cXhtFWiurzF 10.1038/onc.2008.247 18794886
    • A Carracedo PP Pandolfi 2008 The PTEN-PI3K pathway: of feedbacks and cross-talks Oncogene 27 5527 5541 1:CAS:528:DC%2BD1cXhtFWiurzF 10.1038/onc.2008.247 18794886
    • (2008) Oncogene , vol.27 , pp. 5527-5541
    • Carracedo, A.1    Pandolfi, P.P.2
  • 4
    • 0033772326 scopus 로고    scopus 로고
    • Association of splicing defects in PTEN leading to exon skipping or partial intron retention in Cowden syndrome
    • 1:CAS:528:DC%2BD3cXotFShs7g%3D 10.1007/s004390000362 11071384
    • JT Celebi M Wanner XL Ping H Zhang M Peacocke 2000 Association of splicing defects in PTEN leading to exon skipping or partial intron retention in Cowden syndrome Hum Genet 107 234 238 1:CAS:528:DC%2BD3cXotFShs7g%3D 10.1007/s004390000362 11071384
    • (2000) Hum Genet , vol.107 , pp. 234-238
    • Celebi, J.T.1    Wanner, M.2    Ping, X.L.3    Zhang, H.4    Peacocke, M.5
  • 6
    • 0032898096 scopus 로고    scopus 로고
    • PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies
    • DOI 10.1093/hmg/8.2.185
    • PL Dahia RC Aguiar J Alberta JB Kum S Caron H Sill DJ Marsh J Ritz A Freedman C Stiles C Eng 1999 PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies Hum Mol Genet 8 185 193 1:CAS:528:DyaK1MXht12isL4%3D 10.1093/hmg/8.2.185 9931326 (Pubitemid 29054260)
    • (1999) Human Molecular Genetics , vol.8 , Issue.2 , pp. 185-193
    • Dahia, P.L.M.1    Aguiar, R.C.T.2    Alberta, J.3    Kum, J.B.4    Caron, S.5    Sill, H.6    Marsh, D.J.7    Ritz, J.8    Freedman, A.9    Stiles, C.10    Eng, C.11
  • 7
    • 0030698051 scopus 로고    scopus 로고
    • Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours
    • 1:CAS:528:DyaK2sXnt1GhtbY%3D 10.1038/sj.onc.1201591 9366528
    • SA Gayther P Barski SJ Batley L Li KA de Foy SN Cohen BA Ponder C Caldas 1997 Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours Oncogene 15 2119 2126 1:CAS:528:DyaK2sXnt1GhtbY%3D 10.1038/sj.onc.1201591 9366528
    • (1997) Oncogene , vol.15 , pp. 2119-2126
    • Gayther, S.A.1    Barski, P.2    Batley, S.J.3    Li, L.4    De Foy, K.A.5    Cohen, S.N.6    Ponder, B.A.7    Caldas, C.8
  • 9
    • 13944251747 scopus 로고    scopus 로고
    • Alterations of pre-mRNA splicing in cancer
    • DOI 10.1002/gcc.20156
    • Z Kalnina P Zayakin K Silina A Line 2005 Alterations of pre-mRNA splicing in cancer Genes Chromosomes Cancer 42 342 357 1:CAS:528:DC%2BD2MXitVWnsb0%3D 10.1002/gcc.20156 15648050 (Pubitemid 40271278)
    • (2005) Genes Chromosomes and Cancer , vol.42 , Issue.4 , pp. 342-357
    • Kalnina, Z.1    Zayakin, P.2    Silina, K.3    Line, A.4
  • 10
    • 0034976644 scopus 로고    scopus 로고
    • Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas
    • 1:CAS:528:DC%2BD3MXkvFyksbs%3D 11395387
    • K Kurose XP Zhou T Araki SA Cannistra ER Maher C Eng 2001 Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas Am J Pathol 158 2097 2106 1:CAS:528:DC%2BD3MXkvFyksbs%3D 11395387
    • (2001) Am J Pathol , vol.158 , pp. 2097-2106
    • Kurose, K.1    Zhou, X.P.2    Araki, T.3    Cannistra, S.A.4    Maher, E.R.5    Eng, C.6
  • 12
    • 61449229442 scopus 로고    scopus 로고
    • PTEN deficiency is a common defect in juvenile myelomonocytic leukemia
    • 1:CAS:528:DC%2BD1MXivVWqu7c%3D 10.1016/j.leukres.2008.09.036 19010541
    • YL Liu RP Castleberry PD Emanuel 2009 PTEN deficiency is a common defect in juvenile myelomonocytic leukemia Leuk Res 33 671 677 1:CAS:528: DC%2BD1MXivVWqu7c%3D 10.1016/j.leukres.2008.09.036 19010541
    • (2009) Leuk Res , vol.33 , pp. 671-677
    • Liu, Y.L.1    Castleberry, R.P.2    Emanuel, P.D.3
  • 14
    • 0034576144 scopus 로고    scopus 로고
    • Alternative splicing of the human PTEN/MMAC1/TEP1 gene
    • 1:CAS:528:DC%2BD3cXot1yltr8%3D 11121587
    • RM Sharrard NJ Maitland 2000 Alternative splicing of the human PTEN/MMAC1/TEP1 gene Biochim Biophys Acta 1494 282 285 1:CAS:528: DC%2BD3cXot1yltr8%3D 11121587
    • (2000) Biochim Biophys Acta , vol.1494 , pp. 282-285
    • Sharrard, R.M.1    Maitland, N.J.2
  • 16
    • 0030761409 scopus 로고    scopus 로고
    • Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
    • 1:CAS:528:DyaK2sXmtFehs7g%3D 9307275
    • H Tashiro MS Blazes R Wu KR Cho S Bose SI Wang J Li R Parsons LH Ellenson 1997 Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies Cancer Res 57 3935 3940 1:CAS:528: DyaK2sXmtFehs7g%3D 9307275
    • (1997) Cancer Res , vol.57 , pp. 3935-3940
    • Tashiro, H.1    Blazes, M.S.2    Wu, R.3    Cho, K.R.4    Bose, S.5    Wang, S.I.6    Li, J.7    Parsons, R.8    Ellenson, L.H.9
  • 17
    • 0030799909 scopus 로고    scopus 로고
    • Somatic mutations of PTEN in glioblastoma multiforme
    • 1:CAS:528:DyaK2sXmsFChtbs%3D 9331071
    • SI Wang J Puc J Li JN Bruce P Cairns D Sidransky R Parsons 1997 Somatic mutations of PTEN in glioblastoma multiforme Cancer Res 57 4183 4186 1:CAS:528:DyaK2sXmsFChtbs%3D 9331071
    • (1997) Cancer Res , vol.57 , pp. 4183-4186
    • Wang, S.I.1    Puc, J.2    Li, J.3    Bruce, J.N.4    Cairns, P.5    Sidransky, D.6    Parsons, R.7
  • 18
    • 0034112646 scopus 로고    scopus 로고
    • Illegitimate splicing of the NF1 gene in healthy individuals mimics mutation-induced splicing alterations in NF1 patients
    • DOI 10.1007/s004390051043
    • K Wimmer M Eckart H Rehder C Fonatsch 2000 Illegitimate splicing of the NF1 gene in healthy individuals mimics mutation-induced splicing alterations in NF1 patients Hum Genet 106 311 313 1:CAS:528:DC%2BD3cXjtFehsr8%3D 10.1007/s004390051043 10798360 (Pubitemid 30201279)
    • (2000) Human Genetics , vol.106 , Issue.3 , pp. 311-313
    • Wimmer, K.1    Eckart, M.2    Rehder, H.3    Fonatsch, C.4
  • 19
    • 0141974926 scopus 로고    scopus 로고
    • Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences
    • DOI 10.1093/nar/gkg786
    • Q Xu C Lee 2003 Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences Nucleic Acids Res 31 5635 5643 1:CAS:528:DC%2BD3sXns1Cnurs%3D 10.1093/nar/gkg786 14500827 (Pubitemid 37441935)
    • (2003) Nucleic Acids Research , vol.31 , Issue.19 , pp. 5635-5643
    • Xu, Q.1    Lee, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.