Membrane interactions and conformational preferences of human and avian prion N-terminal tandem repeats: The role of copper(II) ions, pH, and membrane mimicking environments

Journal of Physical Chemistry B

Volumn 114, Issue 43, 2010, Pages 13830-13838

  Di Natale, Giuseppe ^a   Pappalardo, Giuseppe ^b   Milardi, Danilo ^b   Sciacca, Michele F M ^a   Attanasio, Francesco ^b   La Mendola, Diego ^b   Rizzarelli, Enrico ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; COMPLEXATION; COPPER; CYTOLOGY; DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; ETHANOL; FLUORESCENCE; LIPID BILAYERS; MAMMALS; MEMBRANES; PEPTIDES; SODIUM SULFATE; SOLUTIONS;

AQUEOUS SOLUTIONS; BINDING DOMAIN; BIOPHYSICAL PROPERTIES; CD SPECTRA; CIRCULAR DICHROISM; COMPARATIVE STUDIES; CONFORMATIONAL CONVERSION; CONFORMATIONAL PREFERENCES; CONFORMATIONAL TRANSITIONS; COPPER (II); COPPER COMPLEXES; COPPER IONS; DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE; ENVIRONMENTAL FACTORS; HUMAN AND CHICKEN PRION PROTEIN; ISOFORMS; MEMBRANE ACTIVITY; MODEL MEMBRANES; MOLECULAR MECHANISM; N-TERMINAL DOMAINS; N-TERMINALS; PEPTIDE STRUCTURES; POLYPROLINE II; PRION PROTEIN; RICH STRUCTURE; SHEET-LIKE STRUCTURE; SIDE CHAIN RESIDUES; SODIUM DODECYL SULFATE; SOLUBLE PEPTIDES; TANDEM REPEATS; THERMOTROPIC PROPERTIES; TRIFLUOROETHANOL; TRP-FLUORESCENCE; UNILAMELLAR VESICLE;

COPPER COMPOUNDS;

EID: 78549264426     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp1033036     Document Type: Article

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