Roles of histidine 31 and tryptophan 34 in the structure, self- association, and folding of murine interleukin-6

Biochemistry

Volumn 36, Issue 20, 1997, Pages 6187-6196

  Matthews, Jacqueline M ^b   Ward, Larry D ^b,c   Hammacher, Annet ^b   Norton, Raymond S ^d   Simpson, Richard J ^a,b  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c Zenyth Therapeutics Limited Australia   (Australia)

^d CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HISTIDINE; INTERLEUKIN 6; MUTANT PROTEIN; TRYPTOPHAN;

ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; HYBRIDOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL ASSAY; CIRCULAR DICHROISM; GUANIDINE; GUANIDINES; HISTIDINE; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-6; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TITRIMETRY; TRYPTOPHAN;

ANIMALIA; MURINAE;

EID: 0030991899     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962939w     Document Type: Article

References (62)

1. Akira, S., Taga, T., & Kishimoto, T. (1993) Adv. Immunol. 54, 1-78.
2. Anglister, J., & Zilber, B. (1990) Biochemistry 29, 921-928.
3. Anil Kumar, Ernst, R. R., & Wüthrich, K. (1980) Biochem. Biophys. Res. Commun. 95, 1-6.
4. Bazan, J. F. (1990) Immunol. Today 11, 350-354.
5. Braunschweiler, L., & Ernst, R. R. (1983) J. Magn. Reson. 53, 521-528.
6. Case, D. A. (1995) J. Biomol. NMR 6, 341-346.
7. Chou, P. Y., & Fasman, G. D. (1978) Annu. Rev. Biochem. 47, 251-276.
8. Clackson, T., & Wells, J. A. (1995) Science 267, 383-386.
9. Clarke, J., & Fersht, A. R. (1993) Biochemistry 32, 4322-4329.
10. Coulie, P. G., Stephens, M., & van Snick, J. (1989) Eur. J. Immunol. 19, 2107-2114.
11. Creamer, T. P., & Rose, G. D. (1995) Protein Sci. 4, 1305-1314.
12. Cunningham, B. C., Ultsch, M., de Vos, A. M., Mulkerrin, M. G., Clauser, K. R., & Wells, J. A. (1991) Science 254, 821-825.
13. deVos, A. M., Ultsch, M., & Kossiakoff, A. A. (1992) Science 255, 306-312.
14. Ehlers, M., Grötzinger, J., de Hon, F. D., Müllberg, J., Brakenhoff, J. P. J., Liu, J., Wollmer, A., & Rose-John, S. (1994) J. Immunol. 153, 1744-1753.
15. Gill, S. G., & von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326.
16. Hammacher, A., Ward, L. D., Weinstock, J., Treutlein, H., Yasukawa, K., & Simpson, R. J. (1994) Protein Sci. 3, 2280-2293.
17. Hammacher, A., Reid, G. E., Moritz, R. L., & Simpson, R. J. (1997) Biomed. Chromatogr. (in press).
18. Hibi, M., Murakami, M., Saito, M., Hirano, T., Taga, T., & Kishimoto, T. (1990) Cell 63, 1149-1157.
19. Hill, C. P., Osslund, T. D., & Eisenberg, D. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 5167-5171.
20. Hirano, T. (1994) in The cytokine handbook (Thomson, A., Ed.) 2nd ed., pp 145-167, Academic Press, New York.
21. Horovitz, A., & Fersht, A. R. (1992) J. Mol. Biol. 224, 733-740.
22. Ito, N., Phillips, S. E. V., Stevens, C., Ogel, Z. B., McPherson, M. J., Keen, J. N., Yadav, K. D. S., & Knowles, P. F. (1991) Nature 350, 87-90.
23. Jasanoff, A., & Weiss, M. A. (1993) Biochemistry 32, 1423-1432.
24. Klein, B., Zhang, X.-G., Lu, Z.-Y., & Bataille, R. (1995) Blood 85, 863-872.
25. Kochoyan, M., Keutmann, H. T., & Weiss, M. A. (1991) Biochemistry 30, 7063-7072.
26. Kossiakoff, A. A., Somers, W., Ultsch, M., Andow, K., Muller, Y. A., & deVos, A. M. (1994) Protein Sci. 3, 1697-1705.
27. Kunkel, T. A., Roberts, J. D., & Zakour, R. A. (1987) Methods Enzymol 154, 367-382.
28. Lakowicz, J. R. (1983) in Principles of Fluorescence Spectroscopy, Plenum Press, New York.
29. Loewenthal, R., Sancho, J., & Fersht, A. R. (1991) Biochemistry 30, 6775-6779.
30. Lovejoy, B., Cascio, D., & Eisenberg, D. (1993) J. Mol. Biol. 234, 640-653.
31. Macura, S., Huang, Y., Suter, D., & Ernst, R. R. (1981) J. Magn. Reson. 43, 259-281.
32. Manoleras, N., & Norton, R. S. (1992) J. Biomol. NMR 2, 485-494.
33. Marion, D., & Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 113, 967-974.
34. Matthews, J. M., Ward, L. D., Zhang, J. G., & Simpson, R. J. (1996) in Techniques in Protein Chemistry (Marshak, D. R., Ed.) Vol. 7, pp 449-457, Academic Press, New York.
35. Morton, C. J., Bai, H., Zhang, J.-G., Hammacher, A., Norton, R. S., Simpson, R. J., & Mabbutt, B. C. (1995) Biochim. Biophys. Acta 1249, 189-203.
36. Mosmann, T. (1983) J. Immunol. Methods 65, 55-63.
37. Muñoz, V., & Serrano, L. (1994) Nat. Struct. Biol. 1, 399-409.
38. Murakami, M., Hibi, M., Nakagawa, N., Nakagawa, T., Yasukawa, K., Yamanishi, K., Taga, T., & Kishimoto, T. (1993) Science 260, 1808-1810.
39. Narazaki, M., & Kishimoto, T. (1994) in Guidebook to cytokines and their receptors (Nicola, N. A., Ed.) pp 1-7, Oxford University Press, Oxford.
40. Nishimura, C., Watanabe, A., Gouda, H., Shimadada, I., & Arata, Y. (1996) Biochemistry 35, 273-281.
41. Paonessa, G., Graziani, R., De Serio, A., Savino, R., Ciapponi, L., Lahm, A., Salvati, A. L., Toniatti, C., & Ciliberto, G. (1995) EMBO J. 14, 1942-1951.
42. Proudfoot, A. E. I., Brown, S. C., Bernard, A. R., Bonnefoy, J.-Y., & Kawashima, E. H. (1993) J. Protein Chem. 12, 489-497.
43. Rucker, S. P., & Shaka, A. J. (1989) Mol. Phys. 68, 509-517.
44. Santoro, M. M., & Bolen, D. W. (1988) Biochemistry 27, 8063-8068.
45. Savino, R., Lahm, A., Salvati, A. L., Ciapponi, L., Sporeno, E., Altamura, S., Paonessa, G., Toniatti, C., & Ciliberto, G. (1994a) EMBO J. 13, 1357-1367.
46. Savino, R., Ciapponi, L., Lahm, A., Demartis, A., Cabibbo, A., Toniatti, C., Delmastro, P., Altamura, S., & Ciliberto, G. (1994b) EMBO J. 13, 5863-5870.
47. Simpson, R. J., Moritz, R. L., van Roost, E., & van Snick, J. (1988a) Biochem. Biophys. Res. Commun. 157, 364-372.
48. Simpson, R. J., Moritz, R. L., Rubira, M. R., & van Snick, J. (1988b) Eur. J. Biochem. 176, 187-197.
49. Simpson, R. J., Hammacher, A., Smith, D. K., Matthews, J. M., & Ward, L. D. (1997) Protein Sci. 6, 929-951.
50. Somers et al. (1997) EMBO J. 16, 989-997.
51. Sprang, S. R., & Bazan, J. F. (1993) Curr. Opin. Struct. Biol. 3, 815-827.
52. Ultsch, M., de Vos, A. M., & Kossiakoff, A. A. (1991) J. Mol. Biol. 22, 306-312.
53. van Snick, J., Cayphas, S., Vink, A., Uyttenhove, C., Coulie, P., Rubira, M. R., & Simpson, R. J. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 9679-9683.
54. Ward, L. D., Zhang, J.-G., Checkly, G., Preston, B., & Simpson, R. J. (1993a) Protein. Sci. 2, 1291-1300.
55. Ward, L. D., Hammacher, A., Zhang, J.-G., Weinstock, J., Yasukawa, K., Morton, C. J., Norton, R. S., & Simpson, R. J. (1993b) Protein Sci. 2, 1472-1481.
56. Ward, L. D., Howlett, G. J., Discolo, G., Yasukawa, K., Hammacher, A., Moritz, R. L., & Simpson, R. J. (1994) J. Biol. Chem. 269, 23286-23289.
57. Ward, L. D., Matthews, J. M., Zhang, J.-G., & Simpson, R. J. (1995) Biochemistry 34, 11652-11659.
58. Wells, J. A. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 1-6.
59. Wery, J. P., Schevitz, R. W., Clawson, D. K., Bobitt, J. L., Dow, E. R., Gamboa, J., Goodson, T., Hermann, R. B., Kramer, R. M., McClure, D. B., Mihelich, E. D., Putnam, J. E., Sharp, J. D., Strak, D. H., Teater, C., Warrick, M. W., & Jones, N. D. (1991) Nature 352, 79-82.
60. Xu, G.-Y., Hong, J., McDonagh, T., Stahl, M., Kay, L. E., Seehra, J., & Cumming, D. A. (1996) J. Biomol. NMR 8, 123-135.
61. Yamasaki, K., Taga, T., Hirata, Y., Yawata, H., Kawanishi, Y., Seed, B., Taniguchi, T., Hirano, T., & Kishimoto, T. (1988) Science 241, 825-828.
62. Zhang, J.-G., Moritz, R. L., Reid, G. E., Ward, L. D., & Simpson, R. J. (1992) Eur. J. Biochem. 207, 903-913.