Suppression of mutagenesis by 8-hydroxy-2′-deoxyguanosine 5′-triphosphate (7,8-dihydro-8-oxo-2′-deoxyguanosine 5′-triphosphate) by human MTH1, MTH2, and NUDT5

Free Radical Biology and Medicine

Volumn 48, Issue 9, 2010, Pages 1197-1201

  Hori, Mika ^a   Satou, Kazuya ^a   Harashima, Hideyoshi ^a   Kamiya, Hiroyuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

8 Hydroxy dGTP; Free radicals; Nucleotide pool; Nucleotide pool sanitization enzymes; Oxidative mutagenesis

Indexed keywords

8 HYDROXY 2' DEOXYGUANOSINE 5' TRIPHOSPHATE; ADENOSINE; CYTIDINE; GUANOSINE; GUANOSINE DERIVATIVE; HYDROLASE; NUCLEOSIDE DIPHOSPHATE LINKED MOIETY X TYPE MOTIF 5 PROTEIN; PLASMID DNA; PROTEIN MTH1; PROTEIN MTH2; SMALL INTERFERING RNA; THYMIDINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL; CONTROLLED STUDY; DNA REPLICATION; ESCHERICHIA COLI; GENE MUTATION; HUMAN; HUMAN CELL; MUTATION RATE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN FUNCTION;

DEOXYGUANINE NUCLEOTIDES; DNA REPAIR ENZYMES; HUMANS; MUTAGENESIS; MUTAGENS; PHOSPHORIC MONOESTER HYDROLASES; PYROPHOSPHATASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSFECTION;

ESCHERICHIA COLI;

EID: 77950338379     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.02.002     Document Type: Article

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