NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity

DNA Repair

Volumn 8, Issue 10, 2009, Pages 1250-1254

  Kamiya, Hiroyuki ^a   Hori, Mika ^a   Arimori, Takao ^b   Sekiguchi, Mutsuo ^c   Yamagata, Yuriko ^b   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c FUKUOKA DENTAL COLLEGE   (Japan)

Author keywords

Nucleotide pool sanitization; NUDT5; Oxidized nucleotide; Substrate recognition

Indexed keywords

2 HYDROXY 2' DEOXYADENOSINE 5 DIPHOSPHATE; 5 FORMYL 2' DEOXYURIDINE 5' DIPHOSPHATE; 5 HYDROXY 2' DEOXYCYTIDINE 5 DIPHOSPHATE; 7,8 DIHYDRO 8 OXO 2' DEOXYGUANOSINE 5' TRIPHOSPHATE; 8 HYDROXY 2' DEOXYADENOSINE 5' DIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; NUCLEOSIDE DIPHOSPHATE KINASE; PROTEIN NUD5; UNCLASSIFIED DRUG;

ARTICLE; ENZYME KINETICS; ENZYME SPECIFICITY; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; PROTEIN STRUCTURE;

DEOXYRIBONUCLEOSIDES; DIPHOSPHATES; HUMANS; HYDROLYSIS; KINETICS; OXIDATION-REDUCTION; PYROPHOSPHATASES; SUBSTRATE SPECIFICITY;

EID: 70149122969     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2009.07.011     Document Type: Article

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