Design of a novel class of biphenyl CETP inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 24, 2010, Pages 7469-7472

  Lu, Zhijian ^a   Napolitano, Joann B ^a   Theberge, Ashleigh ^a   Ali, Amjad ^a   Hammond, Milton L ^a   Tan, Eugene ^a   Tong, Xinchun ^a   Xu, Suoyu S ^a   Latham, Melanie J ^a   Peterson, Laurence B ^a   Anderson, Matt S ^a   Eveland, Suzanne S ^a   Guo, Qiu ^a   Hyland, Sheryl A ^a   Milot, Denise P ^a   Chen, Ying ^a   Sparrow, Carl P ^a   Wright, Samuel D ^a   Sinclair, Peter J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Biphenyl; CETP inhibitors; HDL C

Indexed keywords

ANACETRAPIB; BIPHENYL DERIVATIVE; CARBAMIC ACID; CHOLESTEROL ESTER TRANSFER PROTEIN; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; TORCETRAPIB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; EXPERIMENTAL MODEL; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; TRANSGENIC MOUSE;

ANIMALS; BENZYLAMINES; BIPHENYL COMPOUNDS; CARBAMATES; CHOLESTEROL ESTER TRANSFER PROTEINS; DISEASE MODELS, ANIMAL; DRUG DESIGN; LIPOPROTEINS, HDL; MICE; MICE, TRANSGENIC; STRUCTURE-ACTIVITY RELATIONSHIP;

MUS MUSCULUS;

EID: 78449301593     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.10.019     Document Type: Article

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