2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 1019-1022

  Hunt, Julianne A ^a   Gonzalez, Silvia ^a   Kallashi, Florida ^a   Hammond, Milton L ^a   Pivnichny, James V ^a   Tong, Xinchun ^a   Xu, Suoyu S ^a   Anderson, Matt S ^a   Chen, Ying ^a   Eveland, Suzanne S ^a   Guo, Qiu ^a   Hyland, Sheryl A ^a   Milot, Denise P ^a   Sparrow, Carl P ^a   Wright, Samuel D ^a   Sinclair, Peter J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

2 Arylbenzoxazole; CETP; Cholesteryl ester transfer protein; High density lipoprotein cholesterol; Low density lipoprotien cholesterol; Reverse cholesterol transport

Indexed keywords

2 ARYLBENZOXAZOLE; AMIDE; AMINE; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; UNCLASSIFIED DRUG; ALCOHOL DERIVATIVE; ALKOXYL RADICAL; BENZOXAZOLE DERIVATIVE; CETP PROTEIN, HUMAN; CHOLESTEROL ESTER TRANSFER PROTEIN;

ARTICLE; DRUG BIOAVAILABILITY; DRUG POTENCY; ENZYME INHIBITION; FLUORINATION; IN VITRO STUDY; COMPARATIVE STUDY;

ALCOHOLS; AMIDES; BENZOXAZOLES; CHOLESTEROL ESTER TRANSFER PROTEINS;

EID: 74049135493     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.046     Document Type: Article

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