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Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 24, 2010, Pages 7503-7506

N-Aryl-benzimidazolones as novel small molecule HSP90 inhibitors

(15) Bruncko, Milan a Tahir, Stephen K a Song, Xiaohong a Chen, Jun a Ding, Hong a Huth, Jeffrey R a Jin, Sha a Judge, Russell A a Madar, David J a Park, Chang H a Park, Cheol Min a Petros, Andrew M a Tse, Christin a Rosenberg, Saul H a Elmore, Steven W a

a ABBOTT LABORATORIES (United States)

Author keywords

Benzimidazolone; Cancer; HSP90

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BENZIMIDAZOLE DERIVATIVE; HEAT SHOCK PROTEIN 90 INHIBITOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; DRUG TARGETING; ENZYME INHIBITION; IC 50; PROTEIN DEGRADATION; STRUCTURE ACTIVITY RELATION;

BENZIMIDAZOLES; BINDING SITES; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; HSP90 HEAT-SHOCK PROTEINS; HUMANS; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78449271034 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.10.010 Document Type: Article

Times cited : (36)

References (32)

1
- 0024151897
- S. Lindquist, and E.A. Craig Annu. Rev. Genet. 22 1988 631
- (1988) Annu. Rev. Genet. , vol.22 , pp. 631
- Lindquist, S.¹ Craig, E.A.²

2
- 25844519550
- L. Whitesell, and S.L. Lindquist Nat. Rev. Cancer 5 2005 761
- (2005) Nat. Rev. Cancer , vol.5 , pp. 761
- Whitesell, L.¹ Lindquist, S.L.²

3
- 37649024109
- D.B. Solit, and G. Chiosis Drug Discovery Today 13 2008 38
- (2008) Drug Discovery Today , vol.13 , pp. 38
- Solit, D.B.¹ Chiosis, G.²

4
- 65549085219
- E.M. Karapanagiotou, K. Syrigos, and M.W. Saif Expert Opin. Invest. Drugs 18 2009 161
- (2009) Expert Opin. Invest. Drugs , vol.18 , pp. 161
- Karapanagiotou, E.M.¹ Syrigos, K.² Saif, M.W.³

5
- 0043288724
- J.S. Isaacs, W. Xu, and L. Neckers Cancer Cell 3 2003 213
- (2003) Cancer Cell , vol.3 , pp. 213
- Isaacs, J.S.¹ Xu, W.² Neckers, L.³

6
- 14344264703
- L. Neckers, and K. Neckers Expert Opin. Emerg. Drugs 10 2005 137
- (2005) Expert Opin. Emerg. Drugs , vol.10 , pp. 137
- Neckers, L.¹ Neckers, K.²

7
- 0742287264
- L. Neckers, and S.P. Ivy Curr. Opin. Oncol. 15 2003 419
- (2003) Curr. Opin. Oncol. , vol.15 , pp. 419
- Neckers, L.¹ Ivy, S.P.²

8
- 0035266132
- E. O'Bryan, R. Nimmanapalli, and K. Bhalla Cancer Res. 61 2001 1799
- (2001) Cancer Res. , vol.61 , pp. 1799
- O'Bryan, E.¹ Nimmanapalli, R.² Bhalla, K.³

9
- 0034664030
- P. Pandey, A. Saleh, A. Nakazawa, S. Kumar, S.M. Srinivasula, V. Kumar, R. Weichselbaum, C. Nalin, E.S. Alnemri, D. Kufe, and S. Kharbanda EMBO J. 19 2000 4310
- (2000) EMBO J. , vol.19 , pp. 4310
- Pandey, P.¹ Saleh, A.² Nakazawa, A.³ Kumar, S.⁴ Srinivasula, S.M.⁵ Kumar, V.⁶ Weichselbaum, R.⁷ Nalin, C.⁸ Alnemri, E.S.⁹ Kufe, D.¹⁰ Kharbanda, S.¹¹

10
- 0032515027
- M.H. Cardone, N. Roy, H.R. Stennicke, G.S. Salvesen, T.F. Franke, E. Stanbridge, S. Frisch, and J.C. Reed Science 282 1998 1318
- (1998) Science , vol.282 , pp. 1318
- Cardone, M.H.¹ Roy, N.² Stennicke, H.R.³ Salvesen, G.S.⁴ Franke, T.F.⁵ Stanbridge, E.⁶ Frisch, S.⁷ Reed, J.C.⁸

11
- 1142273472
- P. Workman Trends Mol. Med. 10 2004 47
- (2004) Trends Mol. Med. , vol.10 , pp. 47
- Workman, P.¹

12
- 0141484615
- A. Kamal, L. Thao, J. Sensintaffar, L. Zhang, M.F. Boehm, L.C. Fritz, and F.J. Burrows Nature 425 2003 407
- (2003) Nature , vol.425 , pp. 407
- Kamal, A.¹ Thao, L.² Sensintaffar, J.³ Zhang, L.⁴ Boehm, M.F.⁵ Fritz, L.C.⁶ Burrows, F.J.⁷

13
- 0029992278
- F.U. Hartl Nature 381 1996 571
- (1996) Nature , vol.381 , pp. 571
- Hartl, F.U.¹

14
- 4544254444
- T. Prince, and R.L. Matts J. Biol. Chem. 279 2004 39975
- (2004) J. Biol. Chem. , vol.279 , pp. 39975
- Prince, T.¹ Matts, R.L.²

15
- 0034711270
- M. Marcu, A. Chadli, I. Bouhouche, M. Catelli, and L. Neckers J. Biol. Chem. 275 2000 37181
- (2000) J. Biol. Chem. , vol.275 , pp. 37181
- Marcu, M.¹ Chadli, A.² Bouhouche, I.³ Catelli, M.⁴ Neckers, L.⁵

16
- 4644278673
- H. Wegele, L. Müller, and J. Buchner Rev. Physiol. Biochem. Pharmacol. 151 2004 1
- (2004) Rev. Physiol. Biochem. Pharmacol. , vol.151 , pp. 1
- Wegele, H.¹ Müller, L.² Buchner, J.³

17
- 0028064940
- L. Whitesell, E.G. Mimnaugh, B. De Costa, C.E. Myers, and L.M. Neckers Proc. Natl. Acad. Sci. USA 91 1994 8324
- (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8324
- Whitesell, L.¹ Mimnaugh, E.G.² De Costa, B.³ Myers, C.E.⁴ Neckers, L.M.⁵

18
- 0031875042
- T.W. Schulte, and L.M. Neckers Cancer Chemother. Pharmacol. 42 1998 273
- (1998) Cancer Chemother. Pharmacol. , vol.42 , pp. 273
- Schulte, T.W.¹ Neckers, L.M.²

19
- 0031844350
- T.W. Schulte, S. Akinaga, S. Soga, W. Sullivan, B. Stensgard, D. Toft, and L.M. Neckers Cell Stress Chaperones 3 1998 100
- (1998) Cell Stress Chaperones , vol.3 , pp. 100
- Schulte, T.W.¹ Akinaga, S.² Soga, S.³ Sullivan, W.⁴ Stensgard, B.⁵ Toft, D.⁶ Neckers, L.M.⁷

20
- 33746379315
- L. Neckers Curr. Top. Med. Chem. 6 2006 1163
- (2006) Curr. Top. Med. Chem. , vol.6 , pp. 1163
- Neckers, L.¹

21
- 0029056501
- J.G. Supko, R.L. Hickman, M.R. Grever, and L. Malspeis Cancer Chemother. Pharmacol. 36 1995 305
- (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 305
- Supko, J.G.¹ Hickman, R.L.² Grever, M.R.³ Malspeis, L.⁴

22
- 33746365169
- G. Chiosis Curr. Top. Med. Chem. 6 2006 1183
- (2006) Curr. Top. Med. Chem. , vol.6 , pp. 1183
- Chiosis, G.¹

23
- 33746341544
- E. McDonald, K. Jones, P.A. Brough, M.J. Drysdale, and P. Workman Curr. Top. Med. Chem. 6 2006 1193
- (2006) Curr. Top. Med. Chem. , vol.6 , pp. 1193
- McDonald, E.¹ Jones, K.² Brough, P.A.³ Drysdale, M.J.⁴ Workman, P.⁵

24
- 33644979098
- M. Wang, G. Shen, and B.S.J. Blagg Bioorg. Med. Chem. Lett. 169 2006 2459
- (2006) Bioorg. Med. Chem. Lett. , vol.169 , pp. 2459
- Wang, M.¹ Shen, G.² Blagg, B.S.J.³

25
- 0029671016
- M. Holland, P.D. Langton, N.B. Standen, and J.P. Boyle Br. J. Pharmacol. 117 1996 119
- (1996) Br. J. Pharmacol. , vol.117 , pp. 119
- Holland, M.¹ Langton, P.D.² Standen, N.B.³ Boyle, J.P.⁴

26
- 34248166042
- S.Y. Sharp, Ch. Prodromou, K. Boxall, M.V. Powers, J.L. Holmes, G. Box, T.P. Matthews, K.-M.J. Cheung, A. Kalusa, K. James, A. Hayes, A. Hardcastle, B. Dymock, P.A. Brough, X. Barril, J.E. Cansfield, L. Wright, A. Surgenor, N. Foloppe, R.E. Hubbard, W. Aherne, L. Pearl, K. Jones, E. McDonald, F. Raynaud, S. Eccles, M. Drysdale, and P. Workman Mol. Cancer Ther. 64 2007 1198
- (2007) Mol. Cancer Ther. , vol.64 , pp. 1198
- Sharp, S.Y.¹ Prodromou, C.² Boxall, K.³ Powers, M.V.⁴ Holmes, J.L.⁵ Box, G.⁶ Matthews, T.P.⁷ Cheung, K.-M.J.⁸ Kalusa, A.⁹ James, K.¹⁰ Hayes, A.¹¹ Hardcastle, A.¹² Dymock, B.¹³ Brough, P.A.¹⁴ Barril, X.¹⁵ Cansfield, J.E.¹⁶ Wright, L.¹⁷ Surgenor, A.¹⁸ Foloppe, N.¹⁹ Hubbard, R.E.²⁰ more..

27
- 21244505104
- B.W. Dymock, X. Barril, P.A. Brough, J.E. Cansfield, A. Massey, E. McDonald, R.E. Hubbard, A. Surgenor, S.D. Roughley, P. Webb, P. Workman, L. Wright, and M.J. Drysdale J. Med. Chem. 48 2005 4212
- (2005) J. Med. Chem. , vol.48 , pp. 4212
- Dymock, B.W.¹ Barril, X.² Brough, P.A.³ Cansfield, J.E.⁴ Massey, A.⁵ McDonald, E.⁶ Hubbard, R.E.⁷ Surgenor, A.⁸ Roughley, S.D.⁹ Webb, P.¹⁰ Workman, P.¹¹ Wright, L.¹² Drysdale, M.J.¹³

28
- 0345707575
- W. Xu, X. Yuan, Y.J. Jung, Y. Yang, A. Basso, N. Rosen, E.J. Chung, J. Trepel, and L. Neckers Cancer Res. 63 2003 7777
- (2003) Cancer Res. , vol.63 , pp. 7777
- Xu, W.¹ Yuan, X.² Jung, Y.J.³ Yang, Y.⁴ Basso, A.⁵ Rosen, N.⁶ Chung, E.J.⁷ Trepel, J.⁸ Neckers, L.⁹

29
- 0032749463
- E. Minet, D. Mottet, G. Michel, I. Roland, M. Raes, J. Remacle, and C. Michiels FEBS Lett. 460 1999 251
- (1999) FEBS Lett. , vol.460 , pp. 251
- Minet, E.¹ Mottet, D.² Michel, G.³ Roland, I.⁴ Raes, M.⁵ Remacle, J.⁶ Michiels, C.⁷

30
- 0035793546
- W. Xu, E. Mimnaugh, M.F.N. Rosser, Ch. Nicchitta, M. Marcu, Y. Yarden, and L. Neckers J. Biol. Chem. 276 2001 3702
- (2001) J. Biol. Chem. , vol.276 , pp. 3702
- Xu, W.¹ Mimnaugh, E.² Rosser, M.F.N.³ Nicchitta, C.⁴ Marcu, M.⁵ Yarden, Y.⁶ Neckers, L.⁷

31
- 15044350606
- M.A. Elo, K. Kaarniranta, H.J. Helminen, and M.J. Lammi Biochim. Biophys. Acta, Mol. Cell Res. 1743 2005 115
- (2005) Biochim. Biophys. Acta, Mol. Cell Res. , vol.1743 , pp. 115
- Elo, M.A.¹ Kaarniranta, K.² Helminen, H.J.³ Lammi, M.J.⁴

32
- 78449268882
- WO 2006010594 A1
- Chene, P.; Floersheimer, A.; Furet, P.; Schoepfer, J. WO 2006010594 A1.
- Chene, P.¹ Floersheimer, A.² Furet, P.³ Schoepfer, J.⁴

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