Radanamycin, a macrocyclic chimera of radicicol and geldanamycin

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 9, 2006, Pages 2459-2462

  Wang, Mingwen ^a   Shen, Gang ^a   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Cancer; Geldanamycin; Hsp90; Inhibitors; Radicicol

Indexed keywords

GELDANAMYCIN; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; MACROCYCLIC COMPOUND; QUINONE DERIVATIVE; RADANAMYCIN; RADICICOL; RESORCINOL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CHIMERA; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; PROTEIN FOLDING; STRUCTURE ACTIVITY RELATION;

BENZOQUINONES; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MACROCYCLIC COMPOUNDS; MACROLIDES; MOLECULAR STRUCTURE; QUINONES; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

MINK CELL FOCUS-FORMING VIRUS;

EID: 33644979098     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.01.086     Document Type: Article

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