In vitro degradation of a poly(propylene fumarate)-based composite material

Biomaterials

Volumn 17, Issue 22, 1996, Pages 2127-2130

  Yaszemski, Michael J ^a,b,e   Payne, Richard G ^a,b   Hayes, Wilson C ^d   Langer, Robert ^b   Mikos, Antonios G ^c  

^a WILFORD HALL MEDICAL CENTER   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c Rice University   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e MAYO CLINIC   (United States)

Author keywords

Bone substitutes; Composite materials; Degradable polymers; Poly(propylene fumarate); tricalcium phosphate

Indexed keywords

BIODEGRADATION; BONE; COMPOSITE MATERIALS; COMPRESSIVE STRENGTH; MECHANICAL TESTING; ORTHOPEDICS; POLYPROPYLENES;

BONE SUBSTITUTES; IN VITRO TESTS; POLY(PROPYLENE FUMARATE); TRABECULAR BONE; TRICALCIUM PHOSPHATE; VINYL PYRROLIDONE;

BIOMATERIALS;

BIOMATERIAL; FUMARIC ACID; POLYPROPYLENE;

ARTICLE; BODY FLUID; BONE PROSTHESIS; DEGRADATION; HUMAN; POLYMERIZATION; PRIORITY JOURNAL; TRABECULAR BONE;

EID: 0030297637     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/0142-9612(96)00008-7     Document Type: Article

References (7)

1. 1 Yaszemski MJ, Payne RG, Hayes WC, Langer R, Mikos AG. The evolution of bone transplantation: molecular, cellular, and tissue strategies to engineer human bone. Biomaterials 1996; 17: 175-185.
2. 2 Yaszemski MJ, Payne RG, Hayes WC, Langer R, Aufdemorte TB, Mikos AG. The ingrowth of new bone tissue and initial mechanical properties of a degrading polymeric composite scaffold. Tissue Eng 1995; 1: 41-52.
3. 3 Goldstein SA, Wilson DL, Sonstegard DA, Matthews LS. The mechanical properties of human tibial trabecular bone as a function of metaphyseal location. J Biomech 1983; 16: 965-969.
4. 4 Yaszemski MJ, The design, synthesis, characterization, and mechanical testing of a novel degradable polymeric biomaterial for use as a bone substitute. Ph.D. Thesis, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, 1995.
5. 5 Yaszemski MJ, Payne RG, Aufdemorte TB, Hayes WC, Langer R, Mikos AG. The in vitro mechanical strength and in vivo bone ingrowth of a degrading polymeric composite biomaterial. In: Mikos AG, Leong KW, Yaszemski MJ, Tamada JA, Radomsky ML, eds. Polymers in Medicine and Pharmacy. MRS Symposium Proceedings, Vol. 394. Pittsburgh: Materials Research Society, 1995: 21-24.
6. 6 Frazier DD, Lathi VK, Gerhart TN, Altobelli DE, Hayes WC. In-vivo degradation of a poly(propylene-fumarate) biodegradable, particulate composite bone cement. In: Mikos AG, Leong KW, Yaszemski MJ, Tamada JA, Radomsky ML, eds. Polymers in Medicine and Pharmacy. MRS Symposium Proceedings, Vol. 394. Pittsburgh: Materials Research Society, 1995: 15-19.
7. 7 Thomson RC, Yaszemski MJ, Powers JM, Mikos AG. Fabrication of biodegradable polymer scaffolds to engineer trabecular bone. J Biomater Sci Polym Edn 1995; 7: 23-38.