Synthesis and in vitro biocompatibility of injectable polyurethane foam scaffolds

Tissue Engineering

Volumn 12, Issue 5, 2006, Pages 1247-1259

  Guelcher, Scott A ^a   Patel, Vishal ^b   Gallagher, Katie M ^c   Connolly, Susan ^b   Didier, Jonathan E ^b   Doctor, John S ^c   Hollinger, Jeffrey O ^b  

^a VANDERBILT UNIVERSITY   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c DUQUESNE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOCOMPATIBILITY; FATTY ACIDS; POROUS MATERIALS; SURGICAL EQUIPMENT; SYNTHESIS (CHEMICAL);

INJECTABLE POLYURETHANE FOAMS; ORTHOPEDIC CLINICAL INDICATIONS; POROUS POLYURETHANE FOAMS; VERTEBRAL COMPRESSION FRACTURES;

POLYURETHANES;

ANION; FATTY ACID; ISOCYANIC ACID DERIVATIVE; LYSINE DERIVATIVE; POLYCAPROLACTONE; POLYESTER; POLYOL; POLYURETHAN FOAM; TERTIARY AMINE;

ARTICLE; BIOCOMPATIBILITY; CATALYST; CELL ADHESION; CELL VIABILITY; CHEMICAL COMPOSITION; CHEMICAL REACTION; COMPRESSION; CONTROLLED STUDY; DENSITY; HUMAN; HUMAN CELL; IN VITRO STUDY; POROSITY; PRIORITY JOURNAL; SYNTHESIS; TEMPERATURE;

ANIMALS; BACTERIAL PROTEINS; BONE SUBSTITUTES; CELL LINE; FRACTURES, COMPRESSION; HUMANS; LIPASE; MATERIALS TESTING; OSTEOPOROSIS; POROSITY; SPINAL FRACTURES;

EID: 33745784435     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.2006.12.1247     Document Type: Article

References (34)

1. Praemer, A., Furner, S., and Rice, D. Musculoskeletal Conditions in the United States. Park Ridge, IL: American Academy of Orthopaedic Surgeons, 1992, p. 85.
2. Adhikari, R., and Gunatillake, P.A., inventors; Commonwealth Scientific and Industrial Research Organization, assignee. Biodegradable polyurethane/urea compositions. Australia patent WO 2004/009227 A2. 2004.
3. Gunatillake, P.A., Adhikari, R., Le, T.P., Danon, S.J., Seymour, K., McFarland, C., Bean, P., Mitchell, S., Dalton, A., Werkmeister, J. Ramshaw, J.A., White, J.F., Glattauer, V., and Tebb, T.A. Injectable biodegradable polyurethanes for tissue engineering. Abstract presented at the Seventh World Biomaterials Congress, Sydney, Australia, 2004.
4. Zhang, J.-Y., Beckman, E.J., Hu, J., Yuang, G.-G., Agarwal, S., and Hollinger, J.O. Synthesis, biodegradability, and biocompatibility of lysine diisocyanate-glucose polymers. Tissue Eng. 8, 771, 2002.
5. Zhang, J.-Y., Beckman, E.J., Piesco, N.J., and Agarwal, S. A new peptide-based urethane polymer: synthesis, biodegradation, and potential to support cell growth in vitro. Biomaterials 21, 1247, 2000.
6. Zhang, J., Doll, B., Beckman, E., and Hollinger, J.O. A biodegradable polyurethane-ascorbic acid scaffold for bone tissue engineering. J. Biomed. Mater. Res. 67A, 389, 2003.
7. Zhang, J., Doll, B., Beckman, J., and Hollinger, J.O. Three-dimensional biocompatible ascorbic acid-containing scaffold for bone tissue engineering. Tissue Eng. 9, 1143, 2003.
8. Bruin, P., Veenstra, G.J., Nijenhuis, A.J., and Pennings, A.J. Design and synthesis of biodegradable poly(ester-urethane) elastomer networks composed of non-toxic building blocks. Makromol. Chem. Rapid Commun. 9, 589, 1988.
9. Bennett, S., Connolly, K., Lee, D.R., Jiang, Y., Buck, D., Hollinger, J.O., and Gruskin, E.A. Initial biocompatibility studies of a novel degradable polymeric bone substitute that hardens in situ. Bone 19, 101S, 1996.
10. VDI-Gesellschaft Kunststofftechnik. Kunststoffe (DIN 24450) 89, A47, 1979.
11. Oertel, G. Polyurethane Handbook. Berlin: Hanser Gardner, 1994.
12. Adhikari, R., Gunatillake, T., Le, T.P., Danon, S.J., Seymour, K., Thissen, H., Werkmeister, J., Ramshaw, J.A., and Jacinta, W. Injectable biodegradable polyurethanes for tissue engineering: effect of phyophorylcholine. Abstract presented at the Seventh World Biomaterials Congress, Sydney, Australia, 2004.
13. Kaplan, W., and Neill, P., inventors; Stepan Company, assignee. Open celled polyurethane foams and methods and compositions for preparing such foams. US patent 6,066,681, 2000.
14. Ferrari, R.J., Sinner, J.W., Bill, J.C., and Brucksch, W.F. Compounding polyurethanes: humid aging can be controlled by choosing the right intermediate. Ind. Eng. Chem. 50, 1041, 1958.
15. Sawhney, A.S., and Hubbell, J.A. Rapidly degraded terpolymers of D,L-lactide, glycolide, and e-caprolactone with increased hydrophilicity by copolymerization with polyethers. J. Biomed. Mater. Res. 24, 1397, 1990.
16. Harris, J.W., and Stocker, H. Handbook of Mathematics and Computational Science. New York: Springer-verlag, 1998.
17. Evans, G., Atkinson, B., and Jameson, G. The Jameson cell. In: Matis, K., ed., Flotation Science and Engineering. New York: Marcel Dekker, 1995, p. 353.
18. Bayer Material Science. Desmopan 385 E ISO Datasheet. Pittsburgh, July 7, 2004.
19. Cutnell, J.D., and Johnson, K.W. Physics. New York: Wiley, 1995.
20. Herrington, R., and Hock, K., eds., Flexible Polyurethane Foams. Freeport, TX: Dow Chemical, 1997.
21. ASTM-International. Designation D3574-01. Standard Test Methods for Flexible Cellular Materials-Slab, Bonded, and Molded Urethane Foams. ASTM Methods 08.02, 360, 2002.
22. Vunjak-Novakovic, G., Obradovic, B., Martin, I., Bursac, P.M., Langer, R., and Freed, L.E. Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering. Biotechnol. Prog. 14, 193, 1998.
23. Szycher, M. Szycher's Handbook of Polyurethanes. Boca Raton: CRC Press, 1999.
24. Kothandaraman, H., Nasar, A.S., and Lakshmi, R.K. Synthesis and thermal dissociation of pheno- and naphthol-blocked diisocyanates. J. Appl. Polymer Sci. 53, 31, 1994.
25. Stuart, B. Infrared Spectroscopy: Fundamentals and Applications. New York: John Wiley, 2004.
26. Freed, L.E., and Vunjak-Novakovic, G. Tissue engineering bioreactors. In: Lanza, R.P., Langer, R., and Vacanti, J., eds., Principles of Tissue Engineering. New York: Academic Press, 2000, p. 143.
27. Fleer, G.J., Cohen Stuart, M.A., Scheutjens, J.M.H.M., Cosgrove, T., and Vincent, B. Polymers at Interfaces. London: Chapman & Hall, 1993.
28. Pettis, G.Y., Kaban, L.B., and Glowacki, J. Tissue response to composite ceramic hydroxyapatite/demineralized bone implants. J. Oral Maxillofac. Surg. 48, 1068, 1990.
29. Hott, M., Noel, B., Bernache-Assolant, D., Rey, C., and Marie, P.J. Proliferation and differentiation of human trabecular osteoblastic cells on hydroxyapatite. J. Biomed. Mater. Res. 37, 508, 1997.
30. Jordan, D., Brownstein, S., Dorey, M., Ho Yuen, V., and Gilberg, S. Fibrovascularization of porous polyethylene (MEDPOR) orbital implant in a rabbit model. Ophthal. Plast. Reconstr. Surg. 20, 136, 2004.
31. Wellisz, T., and Wallace, R.D. Porous polyethylene and its biocompatibility. In: Terino, E.O., and Flowers, R.S., eds., The Art of Alloplastic Facial Contouring. St. Louis: C.V. Mosby, 2000, p. 261.
32. Bigham, W.J., Stanley, P., Cahill, J.M., Curran, R.W., and Perry, A.C. Fibrovascular ingrowth in porous ocular implants: the effect of material composition, porosity, growth factors, and coatings. Ophthal. Plast. Reconstr. Surg. 5, 317, 1999.
33. Sperling, L.H. Introduction to Physical Polymer Science. New York: Wiley-Interscience, 2001.
34. Takagi, S., and Chow, L. Formation of micropores in calcium phosphate cement implants. J. Mater. Sci. Mater. Med. 12, 135, 2001.