Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery

Biomaterials

Volumn 32, Issue 2, 2011, Pages 652-663

  Oba, Makoto ^a   Miyata, Kanjiro ^a   Osada, Kensuke ^b   Christie, R James ^b   Sanjoh, Mai ^b   Li, Weidong ^b   Fukushima, Shigeto ^b   Ishii, Takehiko ^b   Kano, Mitsunobu R ^a   Nishiyama, Nobuhiro ^a   Koyama, Hiroyuki ^a   Kataoka, Kazunori ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Anti angiogenic therapy; Cholesterol; Non viral gene vector; Pancreatic tumor; Polyplex micelle

Indexed keywords

ANTI-ANGIOGENIC THERAPY; BLOOD STREAMS; CELLULAR UPTAKE; GENE DELIVERY; GENE VECTORS; IN-VITRO; IN-VIVO; INTRAVENOUS INJECTIONS; LOW CONCENTRATIONS; MICELLE STABILITY; NONVIRAL; PANCREATIC TUMORS; PLASMID DNA (PDNA); POLYCATIONS; POLYPLEXES; SIDE CHAINS; SOLID TUMORS; SYNERGISTIC EFFECT; THERAPEUTIC PDNA; TRANSFECTION EFFICIENCY; TUMOR GROWTH;

BLOCK COPOLYMERS; CHOLESTEROL; COPOLYMERIZATION; ETHYLENE; ETHYLENE GLYCOL; GENE THERAPY; GENE TRANSFER; MICELLES; POLYETHYLENE OXIDES; TUMORS; VECTORS;

POLYETHYLENE GLYCOLS;

ALPHA METHOXY OMEGA CHOLESTERYL CARBAMATE POLY(ETHYLENE GLYCOL); CHOLESTEROL; COPOLYMER; DIETHYLENETRIAMINE; MACROGOL; N [N (2 AMINOETHYL) 2 AMINOETHYL]ASPARTAMIDE; PLASMID DNA; POLYCATION; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC THERAPY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; FEMALE; FLUORESCENCE CORRELATION SPECTROSCOPY; GENE TARGETING; GENETIC TRANSFECTION; HELA CELL; IN VIVO GENE TRANSFER; MICELLE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PANCREAS ADENOCARCINOMA; PANCREAS TUMOR; PH MEASUREMENT; PRIORITY JOURNAL; TUMOR ESCAPE; TUMOR GROWTH;

ANIMALS; CELL LINE, TUMOR; FEMALE; GENE TRANSFER TECHNIQUES; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICELLES; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; POLYAMINES; POLYETHYLENE GLYCOLS; POLYMERS; SERUM ALBUMIN, BOVINE; TRANSFECTION; ULTRACENTRIFUGATION;

MUS;

EID: 78449236732     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.09.022     Document Type: Article

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