Withaferin A inhibits tumor necrosis factor-α-induced expression of cell adhesion molecules by inactivation of Akt and NF-κB in human pulmonary epithelial cells

International Immunopharmacology

Volumn 9, Issue 5, 2009, Pages 614-619

  Oh, Jung Hwa ^a   Kwon, Taeg Kyu ^a  

^a Keimyung University   (South Korea)

Author keywords

A549 cells; Inflammatory disease; Intercellular adhesion molecule 1; Nuclear factor B; Vascular cell adhesion molecule 1; Withaferin A

Indexed keywords

ACTIN; CELL ADHESION MOLECULE; ENHANCED GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; WITHAFERIN A; ERGOSTEROL; ONCOPROTEIN; WITHANOLIDE;

ARTICLE; CELL ADHESION; CELL STRAIN U937; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; LUNG ALVEOLUS EPITHELIUM; MONOCYTE; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PNEUMONIA; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; U937 CELL LINE; WITHANIA;

CELL ADHESION; ERGOSTEROL; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; PNEUMONIA; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS; VASCULAR CELL ADHESION MOLECULE-1; WITHANIA; WITHANOLIDES;

EID: 63549126249     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.02.002     Document Type: Article

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