Thiol regulation of the production of TNF-α, IL-6 and IL-8 by human alveolar macrophages

European Respiratory Journal

Volumn 14, Issue 1, 1999, Pages 98-105

  Gosset, P ^a   Wallaert, B ^a,b   Tonnel, A B ^a,b   Fourneau, C ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

Alveolar macrophage; Glutathione; Interleukin 6; Interleukin 8; N acetylcysteine; Tumour necrosis factor

Indexed keywords

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; GLUTATHIONE; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; THIOL; TUMOR NECROSIS FACTOR ALPHA;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL LEVEL; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ACETYLCYSTEINE; ADULT; ANTIMETABOLITES; ANTIOXIDANTS; BUTHIONINE SULFOXIMINE; CELLS, CULTURED; DNA PRIMERS; FEMALE; GLUTATHIONE; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; INTRACELLULAR FLUID; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032850726     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3003.1999.14a17.x     Document Type: Article

References (34)

1. Kelley J. Cytokines of the lung. Am Rev Respir Dis 1990; 140: 765-788.
2. Strieter RM, Kunkel SL, Bone RC. Role of tumor necrosis factor-α in disease states and inflammation. Crit Care Med 1993; 21: S447-S463.
3. Baggiolini M, Loetscher P, Moser B. Interleukin-8 and the chemokine family. Int J Immunopharmacol 1995; 17: 103-108.
4. Halliwell B, Gutteridge JMC, Cross CE. Free radicals, antioxidants and human disease: where are we now? J Lab Clin Med 1992; 119: 598-620.
5. Jourd'heil D, Morise Z, Conner EM, Kurose I, Grisham MB. Oxidant-regulation of gene expression in the chronically inflammed intestine. Keio J Med 1997; 46: 10-15.
6. Poli G, Parola M. Oxidative damage and fibrogenesis. Free Radic Biol Med 1997; 22: 287-305.
7. Camandola S, Scavazza A, Leonarduzzi G, et al. Biogenie 4-hydroxy-2-nonenal activates transcription factor AP-1 but not NF-kappa B in cells of the macrophage lineage. Biofactors 1997; 6: 173-179.
8. Remacle J, Raes M, Toussaint O, Renard P, Rao G. Low levels of reactive oxygen species as modulators of cell function. Mutat Res 1995; 316: 103-122.
9. Chaudhri G, Clark IA. Reactive oxygen species facilitate the in vitro and in vivo lipopolysaccharide-induced release of tumor necrosis factor. J Immunol 1989; 143: 1290-1294.
10. Peristeris P, Clark BD, Gatti S, et al. N-acetylcysteine and glutathione as inhibitors of tumor necrosis factor production. Cell Immunol 1992; 140: 390-399.
11. Gatti S, Faggioni R, Echtenacher B, Ghezzi P. Role of tumor necrosis factor and reactive oxygen intermediates in lipopolysaccharide-induced pulmonary oedema and lethality. Clin Exp Immunol 1993; 91: 456-461.
12. Eugui EM, DeLustro B, Rouhafza S, et al. Some antioxidants inhibit, in a co-ordinate fashion the production of tumor necrosis factor-α, IL-1β and IL-6 by human peripheral blood mononuclear cells. Int Immunol 1994; 6: 409-422.
13. DeForge LE, Fantone JC, Kenney JS, Remick DG. Oxygen radical scavengers selectively inhibit interleukin-8 production in human whole blood. J Clin Invest 1992; 90: 2123-2129.
14. Bernard GR. N-acetylcysteine in experimental and clinical acute lung injury. Am J Med 1991; 91: 54-59.
15. Borok Z, Buhl R, Grimes GJ, et al. Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis. Lancet 1991; 338: 215-216.
16. Bernard GR, Lucht WD, Niedermeyer ME, Snapper JR, Ogletree ML, Brigham KL. Effect of N-acetylcysteine on the pulmonary response to endotoxin in the awake sheep and upon in vitro granulocyte function. J Clin Invest 1984; 73: 1772-1784.
17. Hoffer E, Avidor I, Benjaminov O, et al. N-acetylcysteine delays the infiltration of inflammatory cells into the lungs of paraquat-intoxicated rats. Toxicol Appl Pharmacol 1993; 120: 8-12.
18. Neuschwander-Tetri BA, Bellezzo JM, Britton RS, Bacon BR, Fox ES. Thiol regulation of endotoxin-induced release of tumor necrosis factor α from isolated rat Kupffer cells. Biochem J 1996; 320: 1005-1010.
19. Gosset P, Lassalle P, Vanhee D, et al. Production of tumor necrosis factor α and interleukin 6 by human alveolar macrophages exposed in vitro to coal mine dust. Am Rev Respir Cell Mol Biol 1991; 5: 431-436.
20. Aerts C, Wallaert B, Voisin C. In vitro effects of hyperoxia on alveolar type II pneumocytes: inhibition of glutathione synthesis increases hyperoxic cell injury. Exp Lung Res 1992; 18: 845-861.
21. Griffith OW. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinyl-pyridine. Anal Biochem 1980; 106: 207-212.
22. Ruff MR, Gifford GE. Rabbit tumor necrosis factor: mechanism of action. Infect Immun 1981; 31: 380-385.
23. 2-terminal amino acid sequence of a T cell derived lymphokine with growth activity for B cell hybridomas. Proc Natl Acad Sci USA 1986; 83: 9679-9685.
24. Burgunder JM, Varriale A, Lauterburg BH. Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol. Eur J Clin Pharmacol 1989; 36: 127-131.
25. Gressier B, Lebegue S, Gosset P, et al. Protective role of glutathione on α1 proteinase inhibitor inactivation by the myeloperoxidase system. Hypothetic study for therapeutic strategy in the management of smokers' emphysema. Fundam Clin Pharmacol 1994; 8: 518-524.
26. Jensen T, Kharazmi A, Schiotz PO, et al. Effect of oral N-acetylcysteine administration on human blood neutrophil and monocyte function. APMIS 1988; 96: 62-67.
27. Arumoa OI, Halliwell B, Hoey BM, Butler J. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl. Free Radic Biol Med 1989; 6: 593-597.
28. Strieter RM, Remick DG, Ham JM, Colletti LM, Lynch III JP, Kunkel SL. Tumor necrosis factor-alpha gene expression in human whole blood. J Leukoc Biol 1990; 47: 366-370.
29. Schenk H, Klein M, Erdbrügger W, Dröge W, Schulze-Osthoff K. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc Natl Acad Sci USA 1994; 91: 1672-1676.
30. Shakhov AN, Collart MA, Vassali P, Nedospasos SA, Jongeneel CV. Kappa B-type enhancer are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor-α gene in primary macrophages. J Exp Med 1990; 171: 35-41.
31. Hirano T, Akira S, Tasa T, Kishimoto J. Biochemical and clinical aspects of interleukin-6. Immunol Today 1990; 11: 443-445.
32. Douglas KT. Mechanism of action of glutathione-dependent enzymes. Adv Enzymol Relat Areas Mol Biol 1987; 59: 103-167.
33. Sen CK. Redox signaling and the emerging therapeutic potential of thiol antioxidants. Biochem Pharmacol 1998; 55: 1747-1758.
34. Ishikawa Y, Yokoo T, Kitamura M. c-Jun/AP-1, but not NF-Kappa B, is a mediator for oxidant initiated apoptosis in glomerular mesangial cells. Biochem Biophys Res Commun 1997; 17: 496-501.