Body temperature as a mouse pharmacodynamic response to bombesin receptor subtype-3 agonists and other potential obesity treatments

American Journal of Physiology - Endocrinology and Metabolism

Volumn 299, Issue 5, 2010, Pages

  Metzger, Joseph M ^a   Gagen, Karen ^a   Raustad, Kate A ^a   Yang, Liming ^a   White, Amanda ^a   Wang, Sheng Ping ^a   Craw, Stephanie ^a   Liu, Ping ^a   Lanza, Thomas ^a   Lin, Linus S ^a   Nargund, Ravi P ^a   Guan, Xiao Ming ^a   Strack, Alison M ^a   Reitman, Marc L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Drug discovery; Fasting; Metabolic rate; Tachyphylaxis; Thermoregulation

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BOMBESIN RECEPTOR; BOMBESIN RECEPTOR SUBTYPE 3; CANNABINOID 1 RECEPTOR ANTAGONIST; CHOLECYSTOKININ A RECEPTOR STIMULATING AGENT; CHOLECYSTOKININ RECEPTOR STIMULATING AGENT; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTAGONIST; MELANOCORTIN; PROSTAGLANDIN E; SIBUTRAMINE; UNCLASSIFIED DRUG; ANTIOBESITY AGENT;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; ENERGY METABOLISM; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; NUTRITIONAL STATUS; OBESITY; PHARMACODYNAMICS; PRIORITY JOURNAL; SYMPATHETIC TONE; THERMOREGULATION; WEIGHT REDUCTION; WILD TYPE; ANIMAL; C57BL MOUSE; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; EATING; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ANTI-OBESITY AGENTS; BODY TEMPERATURE REGULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ENERGY METABOLISM; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; OBESITY; RECEPTORS, BOMBESIN; WEIGHT LOSS;

EID: 78349297581     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00404.2010     Document Type: Article

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