Analysis of the dihydrofolate reductase-thymidylate synthase gene sequences in Plasmodium vivax field isolates that failed chloroquine treatment

Malaria Journal

Volumn 9, Issue 1, 2010, Pages

  Lee, Won Ja ^a   Kim, Hyung Hwan ^b,e   Choi, Yien Kyoung ^a   Choi, Kyung Mi ^a   Kim, Mi A ^a   Kim, Jung Yeon ^a   Sattabongkot, Jetsumon ^c   Sohn, Youngjoo ^d   Kim, Hyuck ^e   Lee, Jong Koo ^f   Park, Han Sook ^a   Lee, Hyeong Woo ^g  

^a Korea Centers for Disease Control and Prevention   (South Korea)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c ARMED FORCES RESEARCH INSTITUTE OF MEDICAL SCIENCES   (Thailand)

^d Department of Computer and Electronic Physics   (South Korea)

^e International Research Center of Bioscience and Biotechnology   (South Korea)

^f Ministry of Health and Welfare   (South Korea)

^g UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; DIHYDROFOLATE REDUCTASE; GENOMIC DNA; PRIMAQUINE; PYRIMETHAMINE; THYMIDYLATE SYNTHASE; ANTIMALARIAL AGENT; PROTOZOAL DNA; PROTOZOAL PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; DELETION MUTANT; DNA TEMPLATE; DRUG SENSITIVITY; GENE; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; KOREA; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PARASITE ISOLATION; PLASMODIUM VIVAX; PLASMODIUM VIVAX MALARIA; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SHORT TANDEM REPEAT; TREATMENT FAILURE; DNA SEQUENCE; DRUG EFFECT; GENETICS; ISOLATION AND PURIFICATION; MISSENSE MUTATION; PARASITOLOGY; SOUTH KOREA;

ANTIMALARIALS; CHLOROQUINE; DNA MUTATIONAL ANALYSIS; DNA, PROTOZOAN; HUMANS; MALARIA, VIVAX; MUTATION, MISSENSE; PLASMODIUM VIVAX; POLYMERASE CHAIN REACTION; PROTOZOAN PROTEINS; REPUBLIC OF KOREA; SEQUENCE ANALYSIS, DNA; TETRAHYDROFOLATE DEHYDROGENASE; THYMIDYLATE SYNTHASE; TREATMENT FAILURE;

EID: 78349264264     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-9-331     Document Type: Article

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