Dihydrofolate reductase and dihydropteroate synthase genotypes associated with in vitro resistance of Plasmodium falciparum to pyrimethamine, trimethoprim, sulfadoxine, and sulfamethoxazole

American Journal of Tropical Medicine and Hygiene

Volumn 68, Issue 5, 2003, Pages 586-589

  Khalil, Insaf ^a,b   Rønn, Anita M ^b   Alifrangis, Michael ^a,b   Gabar, Haytham A ^c   Satti, Gwiria M H ^d   Bygbjerg, Ib C ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Copenhagen University Hospital ^*  (Denmark)

^c UNIVERSITY OF KHARTOUM   (Sudan)

^d IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FOLIC ACID; PYRIMETHAMINE; SULFADOXINE; SULFAMETHOXAZOLE; TRIMETHOPRIM; ANTIMALARIAL AGENT;

ADOLESCENT; ADULT; AGED; ALLELE; ANTHELMINTIC ACTIVITY; ARTICLE; CODON; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS RESISTANCE; CULTURE MEDIUM; DRUG SENSITIVITY; GENOTYPE; HUMAN; IC 50; IN VITRO STUDY; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; SCHOOL CHILD; SERUM; STATISTICAL SIGNIFICANCE; WILD TYPE; ANIMAL; ANTIBIOTIC RESISTANCE; CHILD; DRUG EFFECT; DRUG RESISTANCE; ENZYMOLOGY; GENETICS; MIDDLE AGED; PARASITOLOGY; POINT MUTATION; REPRODUCIBILITY;

PLASMODIUM FALCIPARUM; PROTOZOA;

ADOLESCENT; ADULT; AGED; ANIMALS; ANTIMALARIALS; CHILD; DIHYDROPTEROATE SYNTHASE; DRUG RESISTANCE; GENOTYPE; HUMANS; MALARIA, FALCIPARUM; MIDDLE AGED; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; POINT MUTATION; PYRIMETHAMINE; REPRODUCIBILITY OF RESULTS; SULFADOXINE; SULFAMETHOXAZOLE; TETRAHYDROFOLATE DEHYDROGENASE; TRIMETHOPRIM; TRIMETHOPRIM RESISTANCE;

EID: 0037794109     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2003.68.586     Document Type: Article

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