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Volumn 68, Issue 5, 2003, Pages 586-589

Dihydrofolate reductase and dihydropteroate synthase genotypes associated with in vitro resistance of Plasmodium falciparum to pyrimethamine, trimethoprim, sulfadoxine, and sulfamethoxazole

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FOLIC ACID; PYRIMETHAMINE; SULFADOXINE; SULFAMETHOXAZOLE; TRIMETHOPRIM; ANTIMALARIAL AGENT;

EID: 0037794109     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2003.68.586     Document Type: Article
Times cited : (60)

References (26)
  • 3
  • 4
    • 0000841123 scopus 로고
    • Evidence that a point mutation in dihydrofolate reductase thymidylate synthase confers resistance to pyrimethamine in falciparum malaria
    • Peterson D, Walliker D, Wellems T, 1988. Evidence that a point mutation in dihydrofolate reductase thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci U S A 85: 9114-9118.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 9114-9118
    • Peterson, D.1    Walliker, D.2    Wellems, T.3
  • 5
    • 0024460302 scopus 로고
    • Point mutations in the dihydrofolate reductase thymidylate synthase as molecular basis for pyrimethamine resistance in P. falciparum
    • Zolg J, Plitt J, Chen G, Palmer S, 1989. Point mutations in the dihydrofolate reductase thymidylate synthase as molecular basis for pyrimethamine resistance in P. falciparum. Mol Biochem Parasitol 36: 253-262.
    • (1989) Mol Biochem Parasitol , vol.36 , pp. 253-262
    • Zolg, J.1    Plitt, J.2    Chen, G.3    Palmer, S.4
  • 6
    • 0028021624 scopus 로고
    • Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: DHPS gene in line of human malaria parasite P. falciparum with differing resistance to sulfadoxine
    • Brooks D, Wang P, Read M, Watkins W, Sims P, Hyde J, 1994. Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: DHPS gene in line of human malaria parasite P. falciparum with differing resistance to sulfadoxine. Eur J Biochem 224: 397-405.
    • (1994) Eur J Biochem , vol.224 , pp. 397-405
    • Brooks, D.1    Wang, P.2    Read, M.3    Watkins, W.4    Sims, P.5    Hyde, J.6
  • 7
    • 0031029877 scopus 로고    scopus 로고
    • Sulfadoxine resistance in human malaria parasite P. falciparum is determined by mutations in the dihydropteroate synthase gene and an additional factor associated with folate utilisation
    • Wang P, Read M, Sims P, Hyde J, 1997. Sulfadoxine resistance in human malaria parasite P. falciparum is determined by mutations in the dihydropteroate synthase gene and an additional factor associated with folate utilisation. Mol Microbiol 23: 979-986.
    • (1997) Mol Microbiol , vol.23 , pp. 979-986
    • Wang, P.1    Read, M.2    Sims, P.3    Hyde, J.4
  • 8
    • 0025263958 scopus 로고
    • Amino acids in the dihydrofolate reductase thymidylate synthase gene of P. falciparum involved in pyrimethamine resistance
    • Foote S, Galatis D, Cowman A, 1990. Amino acids in the dihydrofolate reductase thymidylate synthase gene of P. falciparum involved in pyrimethamine resistance. Proc Natl Acad Sci U S A 87: 3014-3017.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 3014-3017
    • Foote, S.1    Galatis, D.2    Cowman, A.3
  • 9
    • 0025252334 scopus 로고
    • Molecular basis of differential resistance to cycloguanil and pyrimethamine in P. falciparum malaria
    • Peterson D, Milhous W, Wellems T, 1990. Molecular basis of differential resistance to cycloguanil and pyrimethamine in P. falciparum malaria. Proc Natl Acad Sci U S A 87: 3018-3022.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 3018-3022
    • Peterson, D.1    Milhous, W.2    Wellems, T.3
  • 10
    • 1242327074 scopus 로고
    • Treatment of acute falciparum malaria with sulfalene and trimethoprim
    • Martin P, Arnold J, 1986. Treatment of acute falciparum malaria with sulfalene and trimethoprim. JAMA 203: 134-138.
    • (1986) JAMA , vol.203 , pp. 134-138
    • Martin, P.1    Arnold, J.2
  • 11
    • 0022479388 scopus 로고
    • The susceptibility of P. falciparum to sulfadoxine and pyrimethamine: Correlation of in vivo and in vitro studies
    • Schapira A, Bygbjerg IC, Jepsen S, Flachs H, Bentzon A, 1986. The susceptibility of P. falciparum to sulfadoxine and pyrimethamine: correlation of in vivo and in vitro studies. Am J Trop Med Hyg 35: 239-245.
    • (1986) Am J Trop Med Hyg , vol.35 , pp. 239-245
    • Schapira, A.1    Bygbjerg, I.C.2    Jepsen, S.3    Flachs, H.4    Bentzon, A.5
  • 12
    • 0023084256 scopus 로고
    • In vitro susceptibility of P. falciparum to pyrimethamine, sulfadoxine, trimethoprim and sulfamethoxazole singly and in combination
    • Petersen E, 1987. In vitro susceptibility of P. falciparum to pyrimethamine, sulfadoxine, trimethoprim and sulfamethoxazole singly and in combination. Trans R Soc Trop Med Hyg 81: 238-241.
    • (1987) Trans R Soc Trop Med Hyg , vol.81 , pp. 238-241
    • Petersen, E.1
  • 13
    • 0017751397 scopus 로고
    • Plasmodium falciparum in culture; use of outdated erythrocytes and description of the candle jar method
    • Jensen JB, Trager W, 1977. Plasmodium falciparum in culture; use of outdated erythrocytes and description of the candle jar method. J Parasitol 63: 883-886.
    • (1977) J Parasitol , vol.63 , pp. 883-886
    • Jensen, J.B.1    Trager, W.2
  • 15
    • 0031127302 scopus 로고    scopus 로고
    • Titration of heparinase for the removal of the PCR inhibitory effect of heparin in DNA samples
    • Taylor A, 1997. Titration of heparinase for the removal of the PCR inhibitory effect of heparin in DNA samples. Mol Ecol 6: 383-385.
    • (1997) Mol Ecol , vol.6 , pp. 383-385
    • Taylor, A.1
  • 16
    • 0032765836 scopus 로고    scopus 로고
    • P. falciparum: Selection of serine 108 of dhfr during treatment uncomplicated malaria with cotrimoxazole in Ugandan children
    • Jelinek T, Kilian A, Curtis J, Duraisingh M, Kabagambe G, Warhurst D, 1999. P. falciparum: selection of serine 108 of dhfr during treatment uncomplicated malaria with cotrimoxazole in Ugandan children. Am J Trop Med Hyg 61: 125-130.
    • (1999) Am J Trop Med Hyg , vol.61 , pp. 125-130
    • Jelinek, T.1    Kilian, A.2    Curtis, J.3    Duraisingh, M.4    Kabagambe, G.5    Warhurst, D.6
  • 17
    • 0026006245 scopus 로고
    • Prevalence of dihydrofolate reductase Asp-108 mutation as basis for pyrimethamine resistant falciparum malaria in the Brazilian Amazon
    • Peterson D, Santi M, Povoa V, Scalvosa V, Rosario D, Wellems T, 1991. Prevalence of dihydrofolate reductase Asp-108 mutation as basis for pyrimethamine resistant falciparum malaria in the Brazilian Amazon. Am J Trop Med Hyg 45: 492-497.
    • (1991) Am J Trop Med Hyg , vol.45 , pp. 492-497
    • Peterson, D.1    Santi, M.2    Povoa, V.3    Scalvosa, V.4    Rosario, D.5    Wellems, T.6
  • 18
    • 0028872311 scopus 로고
    • Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in P. falciparum
    • Basco L, Eldin P, Wilson CJ, Le Brase J, Mazabrand A, 1995. Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in P. falciparum. Mol Biochem Parasitol 69: 135-138.
    • (1995) Mol Biochem Parasitol , vol.69 , pp. 135-138
    • Basco, L.1    Eldin, P.2    Wilson, C.J.3    Le Brase, J.4    Mazabrand, A.5
  • 19
    • 0031963057 scopus 로고    scopus 로고
    • Kenyan P. falciparum isolates: Correlation between pyrimethamine and cycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain
    • Nzila-Mounda A, Mberu E, Sibley C, Plowe C, Winstanley P, Watkins W, 1998. Kenyan P. falciparum isolates: correlation between pyrimethamine and cycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain. Antimicrob Agent Chemother 44: 164-169.
    • (1998) Antimicrob Agent Chemother , vol.44 , pp. 164-169
    • Nzila-Mounda, A.1    Mberu, E.2    Sibley, C.3    Plowe, C.4    Winstanley, P.5    Watkins, W.6
  • 21
    • 0035211422 scopus 로고    scopus 로고
    • Distinguishing P. falciparum treatment failures from re-infections by using polymerase chain reaction genotyping in a holoendemic area in Northeastern Tanzania
    • Magesa SM, Mdira KY, Farnert A, Simonsen PE, Bygbjerg IC, Jakobsen PH, 2001. Distinguishing P. falciparum treatment failures from re-infections by using polymerase chain reaction genotyping in a holoendemic area in Northeastern Tanzania. Am J Trop Med Hyg 65: 477-483.
    • (2001) Am J Trop Med Hyg , vol.65 , pp. 477-483
    • Magesa, S.M.1    Mdira, K.Y.2    Farnert, A.3    Simonsen, P.E.4    Bygbjerg, I.C.5    Jakobsen, P.H.6
  • 23
    • 0021249879 scopus 로고
    • Synergistic antimalarial activity of pyrimethamine and sulfadoxine against P. falciparum in vitro
    • Chulay JD, Watkins WM, Sixsmith DG, 1984. Synergistic antimalarial activity of pyrimethamine and sulfadoxine against P. falciparum in vitro. Am J Trop Med Hyg 33: 325-330.
    • (1984) Am J Trop Med Hyg , vol.33 , pp. 325-330
    • Chulay, J.D.1    Watkins, W.M.2    Sixsmith, D.G.3
  • 24
    • 0021965988 scopus 로고
    • Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by para-aminobenzoic acid, para-aminobenzoylglutamic acid and folic acid
    • Watkins W, Sixsmith D, Chulay J, Spencer H, 1985. Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by para-aminobenzoic acid, para-aminobenzoylglutamic acid and folic acid. Mol Biochem Parasitol 14: 55-61.
    • (1985) Mol Biochem Parasitol , vol.14 , pp. 55-61
    • Watkins, W.1    Sixsmith, D.2    Chulay, J.3    Spencer, H.4
  • 25
    • 0030868588 scopus 로고    scopus 로고
    • Modified in vitro susceptibility assay for P. falciparum suitable for investigating sulfadoxine resistance
    • Wang P, Sims P, Hyde J, 1997. Modified in vitro susceptibility assay for P. falciparum suitable for investigating sulfadoxine resistance. Parasitology 115: 223-230.
    • (1997) Parasitology , vol.115 , pp. 223-230
    • Wang, P.1    Sims, P.2    Hyde, J.3
  • 26
    • 0035725325 scopus 로고    scopus 로고
    • Evaluation of a new SDX sensitivity assay in vitro for field isolates of P. falciparum
    • Ndounga M, Basco LK, Ringwald P, 2001. Evaluation of a new SDX sensitivity assay in vitro for field isolates of P. falciparum. Trans R Soc Trop Med Hyg 95: 55-57.
    • (2001) Trans R Soc Trop Med Hyg , vol.95 , pp. 55-57
    • Ndounga, M.1    Basco, L.K.2    Ringwald, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.