-
1
-
-
67349192531
-
Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy
-
Burton GJ, Woods AW, Jauniaux E, Kingdom JC. Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy. Placenta 30: 473-482, 2009.
-
(2009)
Placenta
, vol.30
, pp. 473-482
-
-
Burton, G.J.1
Woods, A.W.2
Jauniaux, E.3
Kingdom, J.C.4
-
2
-
-
60249089720
-
Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset preeclampsia
-
Burton GJ, Yung HW, Cindrova-Davies T, Charnock-Jones DS. Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset preeclampsia. Placenta 30, Suppl A: S43-S48, 2009.
-
(2009)
Placenta
, vol.30
, Issue.SUPPL. A
-
-
Burton, G.J.1
Yung, H.W.2
Cindrova-Davies, T.3
Charnock-Jones, D.S.4
-
3
-
-
33646368711
-
N-myc down-regulated gene 1 modulates the response of term human trophoblasts to hypoxic injury
-
DOI 10.1074/jbc.M507330200
-
Chen B, Nelson D, Sadovsky Y. N-myc down-regulated gene 1 modulates the response of term human trophoblasts to hypoxic injury. J Biol Chem 281: 2764-2772, 2006. (Pubitemid 43845740)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.5
, pp. 2764-2772
-
-
Chen, B.1
Nelson, D.M.2
Sadovsky, Y.3
-
4
-
-
0038529602
-
Direct interactions between HIF-1α and Mdm2 modulate p53 function
-
DOI 10.1074/jbc.C200694200
-
Chen D, Li M, Luo J, Gu W. Direct interactions between HIF-1alpha and Mdm2 modulate p53 function. J Biol Chem 278: 13595-13598, 2003. (Pubitemid 36799889)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.16
, pp. 13595-13598
-
-
Chen, D.1
Li, M.2
Luo, J.3
Gu, W.4
-
5
-
-
34250879075
-
Nuclear factor-kappaB, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: Effects of antioxidant vitamins
-
DOI 10.2353/ajpath.2007.061035
-
Cindrova-Davies T, Spasic-Boskovic O, Jauniaux E, Charnock-Jones DS, Burton GJ. Nuclear factor-kappaB, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidant vitamins. Am J Pathol 170: 1511-1520, 2007. (Pubitemid 47339297)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.5
, pp. 1511-1520
-
-
Cindrova-Davies, T.1
Spasic-Boskovic, O.2
Jauniaux, E.3
Charnock-Jones, D.S.4
Burton, G.J.5
-
6
-
-
33846511265
-
Status of p53 in first-trimester cytotrophoblastic cells
-
DOI 10.1093/molehr/gal105
-
Cohen M, Meisser A, Haenggeli L, Irminger-Finger I, Bischof P. Status of p53 in first-trimester cytotrophoblastic cells. Mol Hum Reprod 13: 111-116, 2007. (Pubitemid 46152597)
-
(2007)
Molecular Human Reproduction
, vol.13
, Issue.2
, pp. 111-116
-
-
Cohen, M.1
Meisser, A.2
Haenggeli, L.3
Irminger-Finger, I.4
Bischof, P.5
-
7
-
-
0026008734
-
E-cadherin expression during the differentiation of human trophoblasts
-
Coutifaris C, Kao LC, Sehdev HM, Chin U, Babalola GO, Blaschuk OW, Strauss JF 3rd. E-cadherin expression during the differentiation of human trophoblasts. Development 113: 767-777, 1991. (Pubitemid 21900316)
-
(1991)
Development
, vol.113
, Issue.3
, pp. 767-777
-
-
Coutifaris, C.1
Kao, L.-C.2
Sehdev, H.M.3
Chin, U.N.4
Babalola, G.O.5
Blaschuk, O.W.6
Strauss III, J.F.7
-
8
-
-
0035217486
-
The in-vitro characterization of induced apoptosis in placental cytotrophoblasts and syncytiotrophoblasts
-
DOI 10.1053/plac.2001.0733
-
Crocker IP, Barratt S, Kaur M, Baker PN. The in-vitro characterization of induced apoptosis in placental cytotrophoblasts and syncytiotrophoblasts. Placenta 22: 822-830, 2001. (Pubitemid 33150400)
-
(2001)
Placenta
, vol.22
, Issue.10
, pp. 822-830
-
-
Crocker, I.P.1
Barratt, S.2
Kaur, M.3
Baker, P.N.4
-
9
-
-
0036678830
-
Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53
-
Hansson LO, Friedler A, Freund S, Rudiger S, Fersht AR. Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53. Proc Natl Acad Sci USA 99: 10305-10309, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10305-10309
-
-
Hansson, L.O.1
Friedler, A.2
Freund, S.3
Rudiger, S.4
Fersht, A.R.5
-
10
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
DOI 10.1038/387296a0
-
Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299, 1997. (Pubitemid 27220766)
-
(1997)
Nature
, vol.387
, Issue.6630
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
11
-
-
50049101154
-
Live and let die - Regulation of villous trophoblast apoptosis in normal and abnormal pregnancies
-
Heazell AE, Crocker IP. Live and let die - regulation of villous trophoblast apoptosis in normal and abnormal pregnancies. Placenta 29: 772-783, 2008.
-
(2008)
Placenta
, vol.29
, pp. 772-783
-
-
Heazell, A.E.1
Crocker, I.P.2
-
12
-
-
73949117703
-
Massively regulated genes: The example of TP53
-
Hollstein M, Hainaut P. Massively regulated genes: the example of TP53. J Pathol 220: 1164-173.
-
J Pathol
, vol.220
, pp. 1164-1173
-
-
Hollstein, M.1
Hainaut, P.2
-
13
-
-
34548780897
-
Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX
-
DOI 10.1158/0008-5472.CAN-07-1140
-
Hu B, Gilkes DM, Chen J. Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX. Cancer Res 67: 8810-8817, 2007. (Pubitemid 47437457)
-
(2007)
Cancer Research
, vol.67
, Issue.18
, pp. 8810-8817
-
-
Hu, B.1
Gilkes, D.M.2
Chen, J.3
-
14
-
-
33746974317
-
Enhanced Basal Apoptosis in Cultured Term Human Cytotrophoblasts is Associated with a Higher Expression and Physical Interaction of p53 and Bak
-
DOI 10.1016/j.placenta.2005.11.004, PII S0143400405002900
-
Hu C, Smith S, Pang L, Sadovsky Y, Nelson D. Enhanced basal apoptosis in cultured term human cytotrophoblasts is associated with a higher expression and physical interaction of p53 and Bak. Placenta 27: 978-983, 2006. (Pubitemid 44204031)
-
(2006)
Placenta
, vol.27
, Issue.9-10
, pp. 978-983
-
-
Hu, C.1
Smith, S.D.2
Pang, L.3
Sadovsky, Y.4
Nelson, D.M.5
-
15
-
-
42449111705
-
Epidermal growth factor abrogates hypoxia-induced apoptosis in cultured human trophoblasts through phosphorylation of BAD serine 112
-
DOI 10.1210/en.2007-1253
-
Humphrey RG, Sonnenberg-Hirche C, Smith SD, Hu C, Barton A, Sadovsky Y, Nelson DM. Epidermal growth factor abrogates hypoxia-induced apoptosis in cultured human trophoblasts through phosphorylation of BAD serine 112. Endocrinology 149: 2131-2137, 2008. (Pubitemid 351574531)
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2131-2137
-
-
Humphrey, R.G.1
Sonnenberg-Hirche, C.2
Smith, S.D.3
Hu, C.4
Barton, A.5
Sadovsky, Y.6
Nelson, D.M.7
-
16
-
-
0035062024
-
Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks' gestation
-
DOI 10.1067/mob.2001.111935
-
Jauniaux E, Watson A, Burton G. Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks' gestation. Am J Obstet Gynecol 184: 998-1003, 2001. (Pubitemid 32368122)
-
(2001)
American Journal of Obstetrics and Gynecology
, vol.184
, Issue.5
, pp. 998-1003
-
-
Jauniaux, E.1
Watson, A.2
Burton, G.3
-
17
-
-
0037039319
-
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
-
Kaeser MD, Iggo RD. Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo. Proc Natl Acad Sci USA 99: 95-100, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 95-100
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
18
-
-
66149092109
-
Crystal structures of human MdmX (HdmX) in complex with p53 peptide analogues reveal surprising conformational changes
-
Kallen J, Goepfert A, Blechschmidt A, Izaac A, Geiser M, Tavares G, Ramage P, Furet P, Masuya K, Lisztwan J. Crystal structures of human MdmX (HdmX) in complex with p53 peptide analogues reveal surprising conformational changes. J Biol Chem 284: 8812-8821, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 8812-8821
-
-
Kallen, J.1
Goepfert, A.2
Blechschmidt, A.3
Izaac, A.4
Geiser, M.5
Tavares, G.6
Ramage, P.7
Furet, P.8
Masuya, K.9
Lisztwan, J.10
-
19
-
-
4444305174
-
Homocysteine thiolactone induces apoptosis in cultured human trophoblasts: A mechanism for homocysteine-mediated placental dysfunction?
-
DOI 10.1016/j.ajog.2004.01.037, PII S0002937804000845
-
Kamudhamas A, Pang L, Smith S, Sadovsky Y, Nelson D. Homocysteine thiolactone induces apoptosis in cultured human trophoblasts: a mechanism for homocysteine-mediated placental dysfunction? Am J Obstet Gynecol 191: 563-571, 2004. (Pubitemid 39178715)
-
(2004)
American Journal of Obstetrics and Gynecology
, vol.191
, Issue.2
, pp. 563-571
-
-
Kamudhamas, A.1
Pang, L.2
Smith, S.D.3
Sadovsky, Y.4
Nelson, D.M.5
-
20
-
-
17744384255
-
A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1
-
DOI 10.1016/S1097-2765(01)00176-9
-
Keller DM, Zeng X, Wang Y, Zhang QH, Kapoor M, Shu H, Goodman R, Lozano G, Zhao Y, Lu H. A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1. Mol Cell 7: 283-292, 2001. (Pubitemid 32206496)
-
(2001)
Molecular Cell
, vol.7
, Issue.2
, pp. 283-292
-
-
Keller, D.M.1
Zeng, X.2
Wang, Y.3
Zhang, Q.H.4
Kapoor, M.5
Shu, H.6
Goodman, R.7
Lozano, G.8
Zhao, Y.9
Lu, H.10
-
21
-
-
0022527203
-
Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae
-
Kliman HJ, Nestler JE, Sermasi E, Sanger JM, Strauss JF 3rd. Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology 118: 1567-1582, 1986. (Pubitemid 16078536)
-
(1986)
Endocrinology
, vol.118
, Issue.4
, pp. 1567-1582
-
-
Kliman, H.J.1
Nestler, J.E.2
Sermasi, E.3
-
22
-
-
0037507247
-
P53 inhibitor pifithrin α can suppress heat shock and glucocorticoid signaling pathways
-
DOI 10.1074/jbc.C300011200
-
Komarova EA, Neznanov N, Komarov PG, Chernov MV, Wang K, Gudkov AV. p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways. J Biol Chem 278: 15465-15468, 2003. (Pubitemid 36799652)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.18
, pp. 15465-15468
-
-
Komarova, E.A.1
Neznanov, N.2
Komarov, P.G.3
Chernov, M.V.4
Wang, K.5
Gudkov, A.V.6
-
23
-
-
65549120715
-
Modes of p53 regulation
-
Kruse JP, Gu W. Modes of p53 regulation. Cell 137: 609-622, 2009.
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
24
-
-
77449155637
-
The multiple levels of regulation by p53 ubiquitination
-
Lee JT, Gu W. The multiple levels of regulation by p53 ubiquitination.. Cell Death Differ 17: 86-92.
-
Cell Death Differ
, vol.17
, pp. 86-92
-
-
Lee, J.T.1
Gu, W.2
-
25
-
-
0034128782
-
Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor
-
Levy R, Smith S, Chandler K, Sadovsky Y, Nelson D. Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor. Am J Physiol Cell Physiol 278: C982-C988, 2000. (Pubitemid 30346934)
-
(2000)
American Journal of Physiology - Cell Physiology
, vol.278
, Issue.5
-
-
Levy, R.1
Smith, S.D.2
Chandler, K.3
Sadovsky, Y.4
Nelson, D.M.5
-
26
-
-
0036583261
-
Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression
-
Levy R, Smith SD, Yusuf K, Huettner PC, Kraus FT, Sadovsky Y, Nelson DM. Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression. Am J Obstet Gynecol 186: 1056-1061, 2002.
-
(2002)
Am J Obstet Gynecol
, vol.186
, pp. 1056-1061
-
-
Levy, R.1
Smith, S.D.2
Yusuf, K.3
Huettner, P.C.4
Kraus, F.T.5
Sadovsky, Y.6
Nelson, D.M.7
-
27
-
-
33646794425
-
Keeping p53 in check: Essential and synergistic functions of Mdm2 and Mdm4
-
DOI 10.1038/sj.cdd.4401912, PII 4401912
-
Marine JC, Francoz S, Maetens M, Wahl G, Toledo F, Lozano G. Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4. Cell Death Differ 13: 927-934, 2006. (Pubitemid 43753483)
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.6
, pp. 927-934
-
-
Marine, J.-C.1
Francoz, S.2
Maetens, M.3
Wahl, G.4
Toledo, F.5
Lozano, G.6
-
30
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
DOI 10.1016/S1097-2765(01)00214-3
-
Nakano K, Vousden KH. PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 7: 683-694, 2001. (Pubitemid 32706359)
-
(2001)
Molecular Cell
, vol.7
, Issue.3
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
31
-
-
0032921924
-
Hypoxia limits differentiation and up-regulates expression and activity of prostaglandin H synthase 2 in cultured trophoblast from term human placenta
-
DOI 10.1016/S0002-9378(99)70661-7
-
Nelson DM, Johnson RD, Smith SD, Anteby EY, Sadovsky Y. Hypoxia limits differentiation and up-regulates expression and activity of prostaglandin H synthase 2 in cultured trophoblast from term human placenta. Am J Obstet Gynecol 180: 896-902, 1999. (Pubitemid 29200556)
-
(1999)
American Journal of Obstetrics and Gynecology
, vol.180
, Issue.4
, pp. 896-902
-
-
Nelson, D.M.1
Johnson, R.D.2
Smith, S.D.3
Anteby, E.Y.4
Sadovsky, Y.5
-
32
-
-
0027459154
-
Diagnostic value of blood sampling in fetuses with growth retardation
-
DOI 10.1056/NEJM199303113281004
-
Pardi G, Cetin I, Marconi AM, Lanfranchi A, Bozzetti P, Ferrazzi E, Buscaglia M, Battaglia FC. Diagnostic value of blood sampling in fetuses with growth retardation. N Engl J Med 328: 692-696, 1993. (Pubitemid 23073371)
-
(1993)
New England Journal of Medicine
, vol.328
, Issue.10
, pp. 692-696
-
-
Pardi, G.1
Cetin, I.2
Marconi, A.M.3
Lanfranchi, A.4
Bozzetti, P.5
Ferrazzi, E.6
Buscaglia, M.7
Battaglia, F.C.8
-
33
-
-
23844464086
-
Pericellular oxygen depletion during ordinary tissue culturing, measured with oxygen microsensors
-
DOI 10.1111/j.1365-2184.2005.00345.x
-
Pettersen EO, Larsen LH, Ramsing NB, Ebbesen P. Pericellular oxygen depletion during ordinary tissue culturing, measured with oxygen microsensors. Cell Prolif 38: 257-267, 2005. (Pubitemid 41176578)
-
(2005)
Cell Proliferation
, vol.38
, Issue.4
, pp. 257-267
-
-
Pettersen, E.O.1
Larsen, L.H.2
Ramsing, N.B.3
Ebbesen, P.4
-
34
-
-
77449159578
-
Complex regulation of the transactivation function of hypoxia-inducible factor-1alpha by direct interaction with two distinct domains of the CREB-binding protein/p300
-
Ruas JL, Berchner-Pfannschmidt U, Malik S, Gradin K, Fandrey J, Roeder RG, Pereira T, Poellinger L. Complex regulation of the transactivation function of hypoxia-inducible factor-1alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. J Biol Chem 285: 2601-2609.
-
J Biol Chem
, vol.285
, pp. 2601-2609
-
-
Ruas, J.L.1
Berchner-Pfannschmidt, U.2
Malik, S.3
Gradin, K.4
Fandrey, J.5
Roeder, R.G.6
Pereira, T.7
Poellinger, L.8
-
35
-
-
0030790778
-
Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53
-
DOI 10.1021/bi970759w
-
Sakaguchi K, Sakamoto H, Lewis MS, Anderson CW, Erickson JW, Appella E, Xie D. Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53. Biochemistry 36: 10117-10124, 1997. (Pubitemid 27357721)
-
(1997)
Biochemistry
, vol.36
, Issue.33
, pp. 10117-10124
-
-
Sakaguchi, K.1
Sakamoto, H.2
Lewis, M.S.3
Anderson, C.W.4
Erickson, J.W.5
Appella, E.6
Xie, D.7
-
36
-
-
0034667433
-
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer
-
Salnikow K, Costa M, Figg WD, Blagosklonny MV. Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer. Cancer Res 60: 5630-5634, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 5630-5634
-
-
Salnikow, K.1
Costa, M.2
Figg, W.D.3
Blagosklonny, M.V.4
-
38
-
-
34548303702
-
Hypoxic switch in mitochondrial myeloid cell leukemia factor-1/Mtd apoptotic rheostat contributes to human trophoblast cell death in preeclampsia
-
DOI 10.2353/ajpath.2007.070094
-
Soleymanlou N, Jurisicova A, Wu Y, Chijiiwa M, Ray JE, Detmar J, Todros T, Zamudio S, Post M, Caniggia I. Hypoxic switch in mitochondrial myeloid cell leukemia factor-1/Mtd apoptotic rheostat contributes to human trophoblast cell death in preeclampsia. Am J Pathol 171: 496-506, 2007. (Pubitemid 47344682)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.2
, pp. 496-506
-
-
Soleymanlou, N.1
Jurisicova, A.2
Wu, Y.3
Chijiiwa, M.4
Ray, J.E.5
Detmar, J.6
Todros, T.7
Zamudio, S.8
Post, M.9
Caniggia, I.10
-
39
-
-
0023256330
-
Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses
-
Soothill PW, Nicolaides KH, Campbell S. Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses. Br Med J (Clin Res Ed) 294: 1051-1053, 1987. (Pubitemid 17064787)
-
(1987)
British Medical Journal
, vol.294
, Issue.6579
, pp. 1051-1053
-
-
Soothill, P.W.1
Nicolaides, K.H.2
Campbell, S.3
-
40
-
-
31744432611
-
Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha
-
DOI 10.1093/carcin/bgi256
-
Sparfel L, Van Grevenynghe J, Le Vee M, Aninat C, Fardel O. Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha. Carcinogenesis 27: 656-663, 2006. (Pubitemid 43372894)
-
(2006)
Carcinogenesis
, vol.27
, Issue.3
, pp. 656-663
-
-
Sparfel, L.1
Van Grevenynghe, J.2
Le Vee, M.3
Aninat, C.4
Fardel, O.5
-
41
-
-
55749105875
-
p53-mediated apoptosis of CLL cells: Evidence for a transcription- independent mechanism
-
Steele AJ, Prentice AG, Hoffbrand AV, Yogashangary BC, Hart SM, Nacheva EP, Howard-Reeves JD, Duke VM, Kottaridis PD, Cwynarski K, Vassilev LT, Wickremasinghe RG. p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism. Blood 112: 3827-3834, 2008.
-
(2008)
Blood
, vol.112
, pp. 3827-3834
-
-
Steele, A.J.1
Prentice, A.G.2
Hoffbrand, A.V.3
Yogashangary, B.C.4
Hart, S.M.5
Nacheva, E.P.6
Howard-Reeves, J.D.7
Duke, V.M.8
Kottaridis, P.D.9
Cwynarski, K.10
Vassilev, L.T.11
Wickremasinghe, R.G.12
-
42
-
-
33747620737
-
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
-
DOI 10.1038/nchembio809, PII NCHEMBIO809
-
Strom E, Sathe S, Komarov PG, Chernova OB, Pavlovska I, Shyshynova I, Bosykh DA, Burdelya LG, Macklis RM, Skaliter R, Komarova EA, Gudkov AV. Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nat Chem Biol 2: 474-479, 2006. (Pubitemid 44266309)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.9
, pp. 474-479
-
-
Strom, E.1
Sathe, S.2
Komarov, P.G.3
Chernova, O.B.4
Pavlovska, I.5
Shyshynova, I.6
Bosykh, D.A.7
Burdelya, L.G.8
Macklis, R.M.9
Skaliter, R.10
Komarova, E.A.11
Gudkov, A.V.12
-
43
-
-
10744221485
-
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
-
DOI 10.1126/science.1092472
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, Fotouhi N, Liu EA. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303: 844-848, 2004. (Pubitemid 38174664)
-
(2004)
Science
, vol.303
, Issue.5659
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
44
-
-
0242410719
-
P53- And Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa
-
DOI 10.1126/science.1090072
-
Villunger A, Michalak EM, Coultas L, Mullauer F, Bock G, Ausserlechner MJ, Adams JM, Strasser A. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302: 1036-1038, 2003. (Pubitemid 37386194)
-
(2003)
Science
, vol.302
, Issue.5647
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
48
-
-
0030584088
-
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
-
DOI 10.1016/S0092-8674(00)81382-3
-
Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL. Cell 87: 619-628, 1996. (Pubitemid 26386936)
-
(1996)
Cell
, vol.87
, Issue.4
, pp. 619-628
-
-
Zha, J.1
Harada, H.2
Yang, E.3
Jockel, J.4
Korsmeyer, S.J.5
-
49
-
-
5644299014
-
HIF-1α and p53 as targets of NO in affecting cell proliferation, death and adaptation
-
DOI 10.2174/1566524043359926
-
Zhou J, Schmid T, Brune B. HIF-1alpha and p53 as targets of NO in affecting cell proliferation, death and adaptation. Curr Mol Med 4: 741-751, 2004. (Pubitemid 39369292)
-
(2004)
Current Molecular Medicine
, vol.4
, Issue.7
, pp. 741-751
-
-
Zhou, J.1
Schmid, T.2
Brune, B.3
-
50
-
-
44449137138
-
Cyclic pifithrin-α sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis
-
DOI 10.1593/neo.08262
-
Zuco V, Zunino F. Cyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis. Neoplasia 10: 587-596, 2008. (Pubitemid 351770302)
-
(2008)
Neoplasia
, vol.10
, Issue.6
, pp. 587-596
-
-
Zuco, V.1
Zunino, F.2
|