Cinnamaldehyde ofloxacin-3-ylhydrazone induces apoptosis of human hepatocarcinoma SMMC-7721 cells

Yaoxue Xuebao

Volumn 45, Issue 9, 2010, Pages 1109-1115

  Ren, Zheng ^a,b   Kang, Yu Hua ^b   Shi, Zhen Yu ^a   Huang Fu, Chao Shen ^a   Hu, Guo Qiang ^c   Liu, Bin ^a  

^a Institute of Neurobiology   (China)

^b Huai he Clinical College   (China)

^c HENAN UNIVERSITY   (China)

Author keywords

Apoptosis; Mitochondrial membrane potential; Quinolone derivative; Topoisomerase II

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CINNAMALDEHYDE OFLOXACIN 3 YLHYDRAZONE; DNA TOPOISOMERASE (ATP HYDROLYSING); FQ 16; N (3 PHENYLALLYLIDENE) 6 FLUORO 1,8 (2,1 PROPOXY) 7 (4 METHYLPIPERAZIN 1 YL)QUINOLIN 4(1H) ONE 3 CARBONYLHYDRAZINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CELL PROLIFERATION; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; NICK END LABELING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; CELL PROLIFERATION; DNA TOPOISOMERASES, TYPE II; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR STRUCTURE; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78349231350     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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