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Volumn 7, Issue 2, 2008, Pages 350-360
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CHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo
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Author keywords
[No Author keywords available]
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Indexed keywords
2' FLUORO 6,7 METHYLENEDIOXY 2 PHENYL 4 QUINOLONE;
ANTIBODY;
ANTIMITOTIC AGENT;
ANTINEOPLASTIC AGENT;
APOPTOSIS INDUCING FACTOR;
BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE;
COLCHICINE;
CYCLIN B1;
CYCLIN DEPENDENT KINASE 1;
CYCLIN DEPENDENT KINASE INHIBITOR;
DOXORUBICIN;
MPM2 ANTIBODY;
PACLITAXEL;
QUINOLONE DERIVATIVE;
ROSCOVITINE;
SMALL INTERFERING RNA;
TUBULIN;
UNCLASSIFIED DRUG;
VINCRISTINE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTINEOPLASTIC ACTIVITY;
APOPTOSIS;
ARTICLE;
BINDING SITE;
CANCER CELL;
CANCER INHIBITION;
CELL CYCLE ARREST;
CELL CYCLE G2 PHASE;
CELL CYCLE M PHASE;
CELL DEATH;
CELL LINE;
CELL VIABILITY;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG POTENTIATION;
ENZYME ACTIVATION;
GENE TARGETING;
GROWTH INHIBITION;
HUMAN;
HUMAN CELL;
IC 50;
IMMUNOFLUORESCENCE TEST;
IN VITRO STUDY;
IN VIVO STUDY;
INOCULATION;
LIFESPAN;
LIVER CELL CARCINOMA;
MALE;
MICROSCOPY;
MICROTUBULE ASSEMBLY;
MICROTUBULE ORGANIZING CENTER;
MITOCHONDRION;
MOUSE;
NONHUMAN;
PRIORITY JOURNAL;
TUMOR GROWTH;
ANIMALS;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
APOPTOSIS INDUCING FACTOR;
CARCINOMA, HEPATOCELLULAR;
CASPASES;
CELL DIVISION;
CELL PROLIFERATION;
DIOXOLES;
G2 PHASE;
HUMANS;
LIVER NEOPLASMS;
MALE;
MICE;
MICE, SCID;
MICROTUBULES;
MODELS, BIOLOGICAL;
QUINOLONES;
SUBSTRATE SPECIFICITY;
TUMOR CELLS, CULTURED;
XENOGRAFT MODEL ANTITUMOR ASSAYS;
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EID: 39749168393
PISSN: 15357163
EISSN: None
Source Type: Journal
DOI: 10.1158/1535-7163.MCT-07-2000 Document Type: Article |
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Times cited : (66)
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References (34)
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